A comprehensive review on recent advancements in drug delivery via selenium nanoparticles
Journal of drug targeting,
Год журнала:
2024,
Номер
unknown, С. 1 - 14
Опубликована: Окт. 11, 2024
Nanotechnology
has
significantly
impacted
drug
discovery
and
development
over
the
past
three
decades,
offering
novel
insights
expanded
treatment
options.
Key
to
this
field
is
nanoparticles,
ranging
from
1
100
nanometres,
with
unique
properties
distinct
larger
materials.
Selenium
nanoparticles
(SeNPs)
are
particularly
promising
due
their
low
toxicity
selective
cytotoxicity
against
cancer
cells.
They
have
shown
efficacy
in
reducing
various
cancers
types
mitigating
conditions
like
diabetic
nephropathy
neurological
disorders,
such
as
Alzheimer's
disease.
This
review
highlights
SeNPs'
role
enhancing
delivery
systems,
improving
absorption
of
water-soluble
compounds,
proteins,
peptides,
vaccines,
other
biological
therapies.
By
modifying
nanoparticle
surfaces
targeting
ligands,
can
achieve
precise
site-specific
delivery,
increasing
effectiveness.
SeNPs
be
synthesised
through
physical,
chemical,
methods,
each
advantages
stability,
size,
application
potential.
Additionally,
enhance
immune
responses
reduce
oxidative
stress,
validating
biotherapy
nanomedicine.
Their
ability
target
macrophages
regulate
polarisation
underscores
potential
antimicrobial
Recent
advancements,
mannosylated
for
targeted
exemplify
innovative
nanotechnology
applications
medicine.
Overall,
represent
a
frontier
nanomedicine,
new
avenues
treating
managing
diseases.
Язык: Английский
Applications of Hydrogels in Emergency Therapy
Gels,
Год журнала:
2025,
Номер
11(4), С. 234 - 234
Опубликована: Март 23, 2025
Interest
in
developing
new,
effective
materials
for
emergency
hemostasis
and
wound
healing
is
steadily
increasing,
particularly
use
emergency,
surgical,
military
situations.
Hydrogels,
with
their
unique
retention,
swelling,
biocompatibility
properties,
have
emerged
as
essential
therapy.
This
review
provides
a
comprehensive
examination
of
recent
hydrogel
applications
acute
medical
scenarios,
including
hemostasis,
management,
drug
delivery,
soft
tissue
replacement,
engineering.
We
discuss
the
physicochemical
properties
that
make
hydrogels
suitable
rapid
response
situations,
such
tunable
mechanical
strength,
adhesiveness,
responsiveness
to
environmental
stimuli,
ability
encapsulate
release
therapeutic
agents.
Additionally,
article
explores
advancements
smart
self-healing
antimicrobial
providing
insights
into
potential
revolutionize
care
increase
survival
rates
both
civilian
applications.
Through
critical
evaluation
current
clinical
trials
practical
deployments,
this
highlights
successes
challenges
faced
integrating
protocols,
roadmap
future
research
development
dynamic
field.
Язык: Английский
From preparation to application: Functional carrageenan-based hydrogels for biomedical and sensing uses
Materials Today Chemistry,
Год журнала:
2025,
Номер
45, С. 102668 - 102668
Опубликована: Апрель 1, 2025
Язык: Английский
A comprehensive review on niosomes: novel manufacturing techniques, factors influencing formation, applications and recent advances
Nida Arshad,
Farwa Shaheen,
Iqra Khan
и другие.
International Journal of Polymeric Materials,
Год журнала:
2024,
Номер
unknown, С. 1 - 18
Опубликована: Ноя. 18, 2024
A
huge
variety
of
drugs
having
varying
therapeutic
effects
can
be
encapsulated
into
niosomes
and
delivered
to
patients
in
an
efficient
way.
These
nonionic
vesicles
form
a
double
layer
fluid
media,
enhancing
bioavailability.
Niosomes
prepared
using
various
methods
such
as
the
Reverse
Phase
Evaporation
Technique,
Ether
Injection
Method,
Bubble
Microfluidization,
Hand
Shaking
Sonication,
Multiple
Membrane
Extrusion
Niosome
Formation
from
Proniosomes.
are
used
applications,
including
targeting
bioactive
substances,
neoplasia,
diagnostic
imaging
ophthalmic
drug
delivery
system.
Advancement
will
results
development
smart-stimuli
niosomal
system
that
inhibits
ovarian
cancer
cells,
MCF10-A
cells
by
biofunctionalizing
curcumin,
with
potential
for
more
potent
tumor-inhibitory
effects.
It
also
lead
formation
thermo-responsive
Pluronic®
L64
L64ox
nanosilica
substrate
HER2-positive
breast
treatment.
This
review
aims
analyze
novel
manufacturing
techniques,
factors
influencing
formation,
applications
delivery,
highlighting
their
stability,
bioavailability,
targeted
advantages.
explores
recent
advancements,
responsive
systems
disease
Язык: Английский