An update on the diagnosis and management of non‐IgE‐mediated food allergies in children DOI
Rosan Meyer, Antonella Cianferoni, Marta Vázquez‐Ortiz

и другие.

Pediatric Allergy and Immunology, Год журнала: 2025, Номер 36(3)

Опубликована: Март 1, 2025

Abstract The spectrum of non‐IgE mediated conditions includes well‐defined like Food Protein‐Induced Enterocolitis Syndrome (FPIES), Eosinophilic Oesophagitis (EoE), Enteropathy, and Allergic Proctocolitis, but also the more controversial food protein‐induced dysmotility disorders gastroesophageal reflux disease (FPGORD) constipation (FPC). Typically, reactions are delayed, with symptom onset from hours to days after exposure a culprit food. diagnosis is mostly clinical, elimination followed by reintroduction primary diagnostic method. Apart EoE, these remains challenging, there need develop specific tests. Acute FPIES presents distinct symptoms, misdiagnosis common due poor recognition. In contrast, some presentations, particularly FPGORD FPC, overlap common, often benign gut–brain interaction, previously known as functional gastrointestinal disorders. This raises concerns about overdiagnosis can lead an unnecessary restrictive diet in infants breastfeeding mothers. A systematic approach support registered dietitian/nutritionist recommended ensure nutritional adequacy, suitable alternatives, promote timely introductions when appropriate, where required well prevent deficiencies feeding difficulties. publication aims provide update on non‐IgE‐mediated allergic intends clinicians practical guidance management each condition. authors acknowledge for further research range areas inform best evidence‐based practice. image

Язык: Английский

An update on the diagnosis and management of non‐IgE‐mediated food allergies in children DOI
Rosan Meyer, Antonella Cianferoni, Marta Vázquez‐Ortiz

и другие.

Pediatric Allergy and Immunology, Год журнала: 2025, Номер 36(3)

Опубликована: Март 1, 2025

Abstract The spectrum of non‐IgE mediated conditions includes well‐defined like Food Protein‐Induced Enterocolitis Syndrome (FPIES), Eosinophilic Oesophagitis (EoE), Enteropathy, and Allergic Proctocolitis, but also the more controversial food protein‐induced dysmotility disorders gastroesophageal reflux disease (FPGORD) constipation (FPC). Typically, reactions are delayed, with symptom onset from hours to days after exposure a culprit food. diagnosis is mostly clinical, elimination followed by reintroduction primary diagnostic method. Apart EoE, these remains challenging, there need develop specific tests. Acute FPIES presents distinct symptoms, misdiagnosis common due poor recognition. In contrast, some presentations, particularly FPGORD FPC, overlap common, often benign gut–brain interaction, previously known as functional gastrointestinal disorders. This raises concerns about overdiagnosis can lead an unnecessary restrictive diet in infants breastfeeding mothers. A systematic approach support registered dietitian/nutritionist recommended ensure nutritional adequacy, suitable alternatives, promote timely introductions when appropriate, where required well prevent deficiencies feeding difficulties. publication aims provide update on non‐IgE‐mediated allergic intends clinicians practical guidance management each condition. authors acknowledge for further research range areas inform best evidence‐based practice. image

Язык: Английский

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