Risk of long covid in patients with pre-existing chronic respiratory diseases: a systematic review and meta-analysis

BMJ Open Respiratory Research, Год журнала: 2025, Номер 12(1), С. e002528 - e002528

Опубликована: Янв. 1, 2025

Background An estimated 10–30% of people with COVID-19 experience debilitating long-term symptoms or long covid. Underlying health conditions associated chronic inflammation may increase the risk Methods We conducted a systematic review and meta-analysis to examine whether covid was altered by pre-existing asthma obstructive pulmonary disease (COPD) in adults. identified studies searching PubMed Embase databases from inception 13 September 2024. excluded that focused on children defined only terms respiratory symptoms. used random-effects, restricted maximum likelihood models analyse data pooled 51 studies, which included 43 analyses 30 COPD. The bias assessed using ROBINS-E table. Results found 41% increased odds (95% CI 1.29 1.54); COPD 32% 1.16 1.51). Pre-existing asthma, but not COPD, covid-associated fatigue. observed heterogeneity results related hospitalisation status. Potential confounding inconsistent measurement exposure outcome variables were among limitations. Conclusions Our findings support hypothesis covid, including fatigue outcomes patients asthma. Because targets tract, these inflammatory lower tract could provide mechanistic clues common pathway for development sequelae

Язык: Английский

Persistent Symptoms and Associated Risk Factors of COVID-19: A Cross-Sectional Study in Minia, Upper Egypt

Healthcare, Год журнала: 2025, Номер 13(7), С. 699 - 699

Опубликована: Март 22, 2025

Background: A significant number of COVID-19 survivors around the world have been reporting persistent symptoms following their recovery. Long COVID is recognized as a condition affecting not only respiratory but also gastrointestinal, cardiovascular, neurological, immune, and hematopoietic systems. Objective: This study aimed to describe in six months post-infection Minia, Upper Egypt, investigate associated risk factors. Methods: observational cross-sectional included 189 hospitalized non-hospitalized patients previously diagnosed with COVID-19. Demographic data, symptom severity, comorbidities, were collected. logistic regression analysis was used identify factors long COVID, statistical significance set at p < 0.05. Results: In total, 68.8% participants women, 83.5% reported least one ongoing symptom. The most self-reported fatigue (73.5%) myalgia (45.5%), followed by dyspnea (43.3%). Age an increased developing (OR 1.028, 95% CI 1.003-1.054, = 0.030). Patients who during acute phase had more than twice risks having 2.384, 1.055-5.387, 0.037). Conclusions: substantial proportion continues experience symptoms, primarily constitutional neurological manifestations. Many self-medicating unprescribed antibiotics, highlighting need for public awareness regarding viral infections improper antibiotic use.

Язык: Английский

Prevalence of post-acute sequelae of SARS-CoV-2 infection in people living with HIV: a systematic review with meta-analysis

EClinicalMedicine, Год журнала: 2024, Номер 79, С. 102993 - 102993

Опубликована: Дек. 17, 2024

Язык: Английский