Comprehensive Reviews in Food Science and Food Safety, Год журнала: 2025, Номер 24(2)

Опубликована: Март 1, 2025

The global obesity epidemic has heightened interest in natural solutions, with anti-obesity peptides emerging as promising candidates. Derived from food sources such plants, algae, marine organisms, and products like milk eggs, these combat through various mechanisms but face challenges production scalability. aim of this review is to explore their sources, mechanisms, measurement, synthesis methods, including innovative approaches de novo synthesis, proteomics, bioinformatics. Its unique contribution lies critically analyzing the current state research while highlighting novel techniques practical relevance addressing commercialization challenges, offering valuable insights for advancing peptide development. Diverse methods assessing properties are discussed, encompassing both vitro vivo experimental approaches, well alternatives. also explores integration cutting-edge technologies potential revolutionize scalability cost-effectiveness. Key findings assert that despite great fight against advances identification analysis, scalability, regulatory hurdles, bioavailability issues, high costs, consumer appeal persist. Future should use bioinformatics tools advanced screening identify design enhanced efficacy bioavailability, efficient cost-effective extraction purification sustainable practices utilizing byproducts industry, containing isolated versus whole materials clinical settings.

Язык: Английский