Deciphering the Genetic Landscape: Insights Into the Genomic Signatures of Changle Goose DOI Creative Commons
Hao Chen, Yan Wu,

Yihao Zhu

и другие.

Evolutionary Applications, Год журнала: 2024, Номер 17(8)

Опубликована: Авг. 1, 2024

ABSTRACT The Changle goose (CLG), a Chinese indigenous breed, is celebrated for its adaptability, rapid growth, and premium meat quality. Despite agricultural value, the exploration of genomic attributes has been scant. Our study entailed whole‐genome resequencing 303 geese across CLG five other breeds, revealing distinct genetic diversity metrics. We discovered significant migration events from Xingguo gray to minor gene flow between them. identified regions through selective sweep analysis, correlating with CLG's unique traits. An elevated inbreeding coefficient in CLG, alongside reduced heterozygosity rare single nucleotide polymorphisms (R SNPs ), suggests narrowed diversity. Genomic related reproduction, quality, growth were identified, GATA3 showing strong selection signals A non‐synonymous mutation Sloc2a1 gene, which associated reproductive traits exhibited differences allelic frequency. roles CD82 , CDH8 PRKAB1 development, FABP4 FAF1 ESR1 AKAP12 highlighted. Additionally, Cdkal1 Mfsd14a may influence This comprehensive analysis underpins makeup providing basis conservation informed breeding strategies.

Язык: Английский

The effects and mechanisms of heat stress on mammalian oocyte and embryo development DOI

Lain Lang,

Z. W. Wang,

Bin Liu

и другие.

Journal of Thermal Biology, Год журнала: 2024, Номер 124, С. 103927 - 103927

Опубликована: Авг. 1, 2024

Язык: Английский

Процитировано

2
Genetic parameters and genome-wide association for milk production traits and somatic cell score in different lactation stages of Shanghai Holstein population DOI Creative Commons

Dengying Liu,

Zhong Xu, Wei Zhao

и другие.

Frontiers in Genetics, Год журнала: 2022, Номер 13

Опубликована: Сен. 5, 2022

The aim of this study was to investigate the genetic parameters and architectures six milk production traits in Shanghai Holstein population. data used estimate consisted 1,968,589 test-day records for 305,031 primiparous cows. Among cows with phenotypes, 3,016 were genotyped Illumina Bovine SNP50K BeadChip, GeneSeek 50K LD BeadChip v4, 150K or low-depth whole-genome sequencing. A genome-wide association performed identify quantitative trait loci genes associated population using genotypes imputed sequences both fixed random model circulating probability unification a mixed linear rMVP software. Estimated heritabilities (h2) varied from 0.04 0.14 somatic cell score (SCS), 0.07 0.22 fat percentage (FP), 0.09 0.27 yield (MY), 0.06 0.23 (FY), 0.26 protein (PY), 0.35 (PP), respectively. Within lactation, correlations SCS, FP, MY, FY, PY, PP at different stages lactation estimated regression ranged -0.02 0.99, 0.18 0.01 0.33 highest between adjacent DIM but decreased as got further apart. Candidate included those related ( DGAT1 , MGST1 PTK2 SCRIB ), disease-related LY6K COL22A1 TECPR2 PLCB1 heat stress–related ITGA9 NDST4 HSF1 reproduction-related 7SK DOCK2 ) genes. This has shown that there are differences mechanisms lactation. Therefore, it is necessary conduct research on traits. Our results can also provide theoretical basis subsequent molecular breeding, especially novel loci.

Язык: Английский

Процитировано

5
Deciphering the Genetic Landscape: Insights Into the Genomic Signatures of Changle Goose DOI Creative Commons
Hao Chen, Yan Wu,

Yihao Zhu

и другие.

Evolutionary Applications, Год журнала: 2024, Номер 17(8)

Опубликована: Авг. 1, 2024

ABSTRACT The Changle goose (CLG), a Chinese indigenous breed, is celebrated for its adaptability, rapid growth, and premium meat quality. Despite agricultural value, the exploration of genomic attributes has been scant. Our study entailed whole‐genome resequencing 303 geese across CLG five other breeds, revealing distinct genetic diversity metrics. We discovered significant migration events from Xingguo gray to minor gene flow between them. identified regions through selective sweep analysis, correlating with CLG's unique traits. An elevated inbreeding coefficient in CLG, alongside reduced heterozygosity rare single nucleotide polymorphisms (R SNPs ), suggests narrowed diversity. Genomic related reproduction, quality, growth were identified, GATA3 showing strong selection signals A non‐synonymous mutation Sloc2a1 gene, which associated reproductive traits exhibited differences allelic frequency. roles CD82 , CDH8 PRKAB1 development, FABP4 FAF1 ESR1 AKAP12 highlighted. Additionally, Cdkal1 Mfsd14a may influence This comprehensive analysis underpins makeup providing basis conservation informed breeding strategies.

Язык: Английский

Процитировано

0