
Quality of Life Research, Год журнала: 2023, Номер 33(2), С. 373 - 385
Опубликована: Окт. 27, 2023
Abstract Purpose This qualitative study (GSK study: 213635) was designed to better understand sleep disturbance as experienced by individuals with rheumatoid arthritis (RA) or axial spondyloarthritis (axSpA), and the relationship between pain other aspects of disease activity. Methods Sixty-minute, one-on-one, concept elicitation interviews were conducted 30 participants (15 RA 15 axSpA) from US. Interviews audio-recorded transcribed verbatim. Interview transcripts coded analyzed explore themes related disturbance, relationships among those themes. Results Pain a prominent driver disturbance; 12 (80%) 14 axSpA (93%) reported that impacted their ability fall asleep, while all (100%) stay asleep. Two-thirds (67%) (60%) described bi-directional relationship, whereby worsened further aggravated pain. Factors than pain, such fatigue emotional health, also important contributors (RA: n = 12/15, 80%; axSpA: 14/15, 93%). Participants complex interconnections fatigue, sleep, often labeling these “ vicious cycles ”. Notably, half occurring without understood causes. Conclusion These perspectives collected people suggest reducing disruption directly may offer clinically relevant benefits.
Язык: Английский