Colloids and Interfaces,
Год журнала:
2022,
Номер
6(2), С. 35 - 35
Опубликована: Май 29, 2022
This
research
is
focused
on
the
adsorption
modification
of
detonation
nanodiamond
surfaces
with
antibiotics
for
their
further
use
as
smart
materials
cardiovascular
surgery
purposes,
namely
bioprostheses
modifiers.
Tritium-labeled
amikacin
and
levofloxacin
were
used
tracers
process
control.
We
found
that
nanodiamonds
form
complexes
via
physical
adsorption,
while
in
case
amikacin,
electrostatic
attraction
contributes
to
formation
more
stable
complexes,
even
presence
electrolytes
desorbing
agents
(models
biological
fluids).
Antimicrobial
characterization
nanodiamond–levofloxacin
nanodiamond–amikacin
indicates
a
reduction
dose
an
antimicrobial
agent.
Therefore,
biomaterial
based
DND
basis
will
allow
one
either
avoid
or
significantly
reduce
duration
intensity
postoperative
period,
which
critically
important
from
viewpoint
development
antibiotic
resistance
pathogens.
Pharmaceutics,
Год журнала:
2024,
Номер
16(2), С. 288 - 288
Опубликована: Фев. 18, 2024
Gene
therapeutics
are
promising
for
treating
diseases
at
the
genetic
level,
with
some
already
validated
clinical
use.
Recently,
nanostructures
have
emerged
targeted
delivery
of
material.
Nanomaterials,
exhibiting
advantageous
properties
such
as
a
high
surface-to-volume
ratio,
biocompatibility,
facile
functionalization,
substantial
loading
capacity,
and
tunable
physicochemical
characteristics,
recognized
non-viral
vectors
in
gene
therapy
applications.
Despite
progress,
current
exhibit
notably
low
efficiency.
Progress
nanotechnology
is
essential
to
overcome
extracellular
intracellular
barriers
delivery.
Specific
carbon
nanotubes
(CNTs),
quantum
dots
(CQDs),
nanodiamonds
(NDs),
similar
carbon-based
structures
can
accommodate
diverse
materials
plasmid
DNA
(pDNA),
messenger
RNA
(mRNA),
small
interference
(siRNA),
micro
(miRNA),
antisense
oligonucleotides
(AONs).
To
address
challenges
toxicity
transfection
efficiency,
advancements
features
(CBNs)
imperative.
This
overview
delves
into
three
types
CBNs
employed
drug/gene
systems,
encompassing
their
synthesis
methods,
properties,
biomedical
Ultimately,
we
present
insights
opportunities
within
captivating
realm
using
CBNs.
ACS Nano,
Год журнала:
2022,
Номер
16(6), С. 8513 - 8524
Опубликована: Май 23, 2022
Nanodiamonds
are
at
the
heart
of
a
plethora
emerging
applications
in
areas
ranging
from
nanocomposites
and
tribology
to
nanomedicine
quantum
sensing.
The
development
alternative
synthesis
methods,
better
understanding,
availability
ultrasmall
nanodiamonds
less
than
3
nm
size
with
precisely
engineered
composition,
including
particle
surface
atomic
defects
diamond
crystal
lattice,
would
mark
leap
forward
for
many
existing
future
applications.
Yet
today,
we
unable
accurately
control
nanodiamond
composition
scale,
nor
can
reliably
create
isolate
particles
this
range.
In
perspective,
discuss
recent
advances,
challenges,
opportunities
synthesis,
characterization,
application
nanodiamonds.
We
particularly
focus
on
advantages
bottom-up
these
critically
assess
physicochemical
properties
nanodiamonds,
which
significantly
differ
those
larger
bulk
diamond.
ACS Biomaterials Science & Engineering,
Год журнала:
2021,
Номер
7(10), С. 4718 - 4735
Опубликована: Сен. 29, 2021
As
the
main
load-bearing
structure
in
human
body,
bone
and
cartilage
are
susceptible
to
damage
sports
other
activities.
The
repair
regeneration
of
articular
have
been
extensively
studied
past
decades.
Traditional
approaches
widely
applied
clinical
practice,
but
effect
varies
from
person
may
cause
side
effects.
With
rapid
development
tissue
engineering
regenerative
medicine,
various
biomaterials
show
great
potential
cartilage.
Carbon-based
nanomaterials
solid
materials
with
different
structures
properties
composed
allotropes
carbon,
which
classified
into
zero-,
one-,
two-dimensional
ones.
This
Review
systemically
summarizes
types
carbon-based
nanomaterials,
including
zero-dimensional
(fullerene,
carbon
dots,
nanodiamonds),
one-dimensional
(carbon
nanotubes),
(graphenic
materials)
as
well
their
applications
bone,
cartilage,
osteochondral
regeneration.
Current
limitations
future
perspectives
also
discussed.
ACS Applied Nano Materials,
Год журнала:
2021,
Номер
4(10), С. 9985 - 10005
Опубликована: Окт. 4, 2021
Nanodiamonds
(NDs)
represent
an
emerging
class
of
nanomaterials
that
have
been
used
for
a
variety
applications
including
biosensing
and
imaging,
drug
delivery,
energy
storage
conversion,
quantum
sensing.
Many
these
application
areas
require
precise
control
over
their
ND
surface
properties
to
maximize
and/or
enhance
the
interaction
between
particles
surrounding
environment.
In
this
contribution,
we
review
recent
advances
in
functionalization
techniques
NDs
with
emphasis
on
biological
material.
Desalination,
Год журнала:
2024,
Номер
574, С. 117277 - 117277
Опубликована: Янв. 3, 2024
The
review
concludes
with
a
broad
spectrum
of
practical
applications
concerted
PVDF-CNM
membrane
materials
dedicated
for
liquid
and
gas
separation,
significant
focus
on
the
desalination
process.
research
is
carried
out
in
diverse
science
fields,
merging
chemistry
engineering
toward
frequently
multimodal
functionalities.
Hence,
there
high
demand
comprehensive
these
cutting-edge-materials
from
across
fundamental
sciences
technologies.
main
goals
work
are
linking
structure
PVDF
(phases)
CNMs
(carbon
atom
hybridization)
physico-chemical
properties
PVDF-CNMs
materials.
Moreover,
attention
was
paid
simplicity
generation
having
huge
potential
tuning
various
features
obtained
(e.g.,
hydrophilicity,
mechanical
properties,
catalytic
activity,
bioactivity).
Additionally,
new
directions
exploration
have
been
indicated.
Abstract
Nanodiamonds
(NDs)
are
utilized
for
various
purposes
in
dentistry,
such
as
tissue
regeneration,
gene
therapy,
and
medication
delivery.
Despite
the
examination
of
their
potential
dental
uses,
there
is
currently
no
published
review
summarizing
conducted
investigations.
Additional
investigations
required
to
comprehend
biological
compatibility
NDs
dentistry.
have
been
proven
effective
a
variety
applications
dentistry
because
unique
qualities
target
cell
selectivity,
nanometer
size,
fluorescence.
find
encompassing
roles
directed
reinforcing
polymers,
administering
medications
treating
infections
cancer.
Researchers
also
suggested
use
nanodiamonds
coatings
antibacterial
or
bioactive
implants.
Nevertheless,
on
scarce
insufficient
so
far,
necessitating
significantly
further
studies
envision
It
believed
that
within
ten
years
come,
these
emerging
substances
will
discover
several
kinds
daily
usage
practice.
Nanoscale,
Год журнала:
2021,
Номер
13(31), С. 13375 - 13389
Опубликована: Янв. 1, 2021
A
multifunctional
nanodiamond-based
theranostic
nanoplatform
was
fabricated
that
exhibited
enhanced
mild-temperature
photothermal/chemo
combination
therapy
efficiency
via
an
autophagy
regulation
strategy
against
triple
negative
breast
cancer.
