The roles of extracellular vesicles in mental disorders: information carriers, biomarkers, therapeutic agents DOI Creative Commons

Longkun Wang,

Ruixue Liu, Ying Wang

и другие.

Frontiers in Pharmacology, Год журнала: 2025, Номер 16

Опубликована: Апрель 9, 2025

Mental disorders are complex conditions that encompass various symptoms and types, affecting approximately 1 in 8 people globally. They place a significant burden on both families society as whole. So far, the etiology of mental remains poorly understood, making diagnosis treatment particularly challenging. Extracellular vesicles (EVs) nanoscale particles produced by cells released into extracellular space. contain bioactive molecules including nucleotides, proteins, lipids, metabolites, which can mediate intercellular communication involved physiological pathological processes. Recent studies have shown EVs closely linked to like schizophrenia, major depressive disorder, bipolar playing key role their development, diagnosis, prognosis, treatment. Therefore, based recent research findings, this paper aims describe roles summarize potential applications treatment, providing new ideas for future clinical transformation application EVs.

Язык: Английский

The roles of extracellular vesicles in mental disorders: information carriers, biomarkers, therapeutic agents DOI Creative Commons

Longkun Wang,

Ruixue Liu, Ying Wang

и другие.

Frontiers in Pharmacology, Год журнала: 2025, Номер 16

Опубликована: Апрель 9, 2025

Mental disorders are complex conditions that encompass various symptoms and types, affecting approximately 1 in 8 people globally. They place a significant burden on both families society as whole. So far, the etiology of mental remains poorly understood, making diagnosis treatment particularly challenging. Extracellular vesicles (EVs) nanoscale particles produced by cells released into extracellular space. contain bioactive molecules including nucleotides, proteins, lipids, metabolites, which can mediate intercellular communication involved physiological pathological processes. Recent studies have shown EVs closely linked to like schizophrenia, major depressive disorder, bipolar playing key role their development, diagnosis, prognosis, treatment. Therefore, based recent research findings, this paper aims describe roles summarize potential applications treatment, providing new ideas for future clinical transformation application EVs.

Язык: Английский

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