Small Methods, Год журнала: 2025, Номер unknown

Опубликована: Фев. 11, 2025

Abstract Phage therapy presents a promising solution for combating multidrug‐resistant (MDR) bacterial infections and other bacteria‐related diseases, attributed to their innate ability target lyse bacteria. Recent clinical successes, particularly in treating MDR‐related respiratory post‐surgical infections, validated the therapeutic potential of phage therapy. However, complex microenvironment within human body poses significant challenges activity efficacy vivo. To overcome these barriers, recent advances engineering have aimed enhance targeting accuracy, improve stability survivability, explore synergistic combinations with modalities. This review provides comprehensive overview therapy, emphasizing application engineered phages antibacterial tumor vaccine development. Furthermore, highlights current future trends advancing toward broader applications.

Язык: Английский