Biomolecules,
Год журнала:
2024,
Номер
14(10), С. 1275 - 1275
Опубликована: Окт. 10, 2024
of
Mattinata,
a
rare
and
ancient
Mediterranean
citrus
fruit,
was
investigated
by
sequence
analysis
the
ribosomal
internal
transcribed
spacer
regions,
which
assigns
it
as
variety
Functional Foods in Health and Disease,
Год журнала:
2024,
Номер
14(5), С. 346 - 365
Опубликована: Май 23, 2024
Background:
There
is
mounting
evidence
that
the
intake
of
polyphenols
can
help
prevent
cardiovascular
complications.
Furthermore,
multiple
intakes
different
polyphenol
compounds
are
expected
to
have
a
synergistic
effect.
However,
few
studies
examined
preventive
effect
simultaneous
on
complications
in
healthy
adults.
Objective:
The
present
study
aimed
evaluate
efficacy
daily
70
mg
monoglucosyl
hesperidin
(MH)
alone,
or
combination
with
140
rutin
(MR),
improving
vascular
flexibility.
Methods:
This
8-week
was
conducted
66
male
and
female
participants
relatively
high
body
mass
index
(BMI)
low
were
randomly
assigned
an
MH
group
(MH
alone),
MHMR
(combination
MR),
placebo
by
computer-generated
list
(each
n
=
22).
Participants
took
two
tablets
per
day
either
MH,
during
intervention.
Outcomes
included
function
indices,
capillary
flow,
inflammatory
markers.
Assessment
points
at
4
weeks
(4w)
8
(8w)
Results:
primary
outcome
flow-mediated
dilation.
In
analysis
including
whose
left
brachial-ankle
pulse
wave
velocity
(baPWV)
≥1232.5
cm/s
baseline
per-protocol
set,
showed
significant
improvement
compared
dilation,
maximum
post-avascularization
artery
diameter,
baPWV
average
both
legs),
E-selectin
8w.
Conclusion:
These
results
indicated
MR,
may
act
endothelial
cells
improve
flexibility
adults
lowvascular
(UMIN000046054).
Keywords:
Monoglucosyl
hesperidin;
rutin;
dilation;
E-selectin;
velocity,
index,
Biomolecules,
Год журнала:
2024,
Номер
14(10), С. 1275 - 1275
Опубликована: Окт. 10, 2024
of
Mattinata,
a
rare
and
ancient
Mediterranean
citrus
fruit,
was
investigated
by
sequence
analysis
the
ribosomal
internal
transcribed
spacer
regions,
which
assigns
it
as
variety