Small Phenolic Metabolites at the Nexus of Nutrient Transport and Energy Metabolism

Molecules, Год журнала: 2025, Номер 30(5), С. 1026 - 1026

Опубликована: Фев. 24, 2025

Over time, human metabolism evolved to accommodate the challenges and benefits of plant foods that contain high amounts carbohydrates polyphenols. The latter are typically metabolized into small phenolic metabolites, including acids their endogenous microbial derivatives, influence interconnected metabolic pathways involved in nutrient transport, energy metabolism, neurotransmitter balance. Unlike other natural products, biological effects arise from weak interactions with multiple molecular rather than a single high-affinity receptor, making them versatile regulators health. These compounds also modulate glucose transporters carbohydrate playing crucial role postprandial insulin responses. This review addresses critical metabolites health, focus on homeostasis, sensitivity, metabolism. Incorporating polyphenols dietary strategies offers significant potential for improving reducing disorder risks, promoting whole-body homeostasis. Furthermore, understanding how interact is essential developing future effective nutritional support

Язык: Английский

Thiosulphate Sulfurtransferase: Biological Roles and Therapeutic Potential

Redox Biology, Год журнала: 2025, Номер unknown, С. 103595 - 103595

Опубликована: Март 1, 2025

Язык: Английский