Results in Chemistry, Год журнала: 2024, Номер unknown, С. 102011 - 102011
Опубликована: Дек. 1, 2024
Язык: Английский
Foods, Год журнала: 2023, Номер 12(24), С. 4470 - 4470
Опубликована: Дек. 13, 2023
Fish processing by-products such as frames, trimmings, and viscera of commercial fish species are rich in proteins. Thus, they could potentially be an economical source proteins that may used to obtain bioactive peptides functional protein hydrolysates for the food nutraceutical industries. The structure, composition, biological activities depend on freshness actual composition material. Peptides isolated from fishery showed antioxidant activity. Changes hydrolysis parameters changed sequence properties determined their physiological functions. optimization value production costs must considered each particular marine specific applications. This review will discuss prepared using potential It also reviews structure-activity relationships activity well challenges use hydrolysate production.
Язык: Английский
Процитировано
42
Food Additives & Contaminants Part A, Год журнала: 2025, Номер unknown, С. 1 - 6
Опубликована: Янв. 9, 2025
Brazil is an influential and successful food-producing country, where we can highlight artisanal cheeses gaining visibility in foreign markets. Some of these are made from raw milk, making them susceptible to contamination by microorganisms, including fungi, which produce harmful mycotoxins. Feed contaminated with aflatoxin B1, when consumed dairy animals, metabolized transformed into M1 (AFM1), excreted milk. Therefore, the aim this research was investigate occurrence AFM1 two Brazilian states: Minas Gerais São Paulo. This toxin extracted 10 g sample 50 ml pepsin solution. An aliquot extract passed through immunoaffinity column, eluted, dried under nitrogen. For analysis detection quantification AFM1, High-Performance Liquid Chromatography (HPLC) fluorescence system used. A total 130 samples were analyzed; 41 tested positive for while 89 negative. Out samples, only above maximum tolerated limit ANVISA 2.5 µg/kg. These results show importance investigating cheeses, aiming prevent increase food safety.
Язык: Английский
Процитировано
0
Food and Bioprocess Technology, Год журнала: 2025, Номер unknown
Опубликована: Янв. 23, 2025
Язык: Английский
Процитировано
0
Critical Reviews in Food Science and Nutrition, Год журнала: 2025, Номер unknown, С. 1 - 24
Опубликована: Апрель 12, 2025
Plant-based peptides can be obtained from natural and climate-friendly sources. These show various bioactivities including antioxidant activity. Oxidative stress has an impact on the gut microbiota causing inflammation, insulin resistance, osteoporosis, cancer, several chronic diseases like type 2 diabetes, arthritis, hypertension, atherosclerosis. Therefore, may significantly affect oxidative as a potential alternative to conventional medication. The production of plant-based protein sources through innovative approaches provide promising strategies improve microbiota. Recent studies in (PBAP) focus their advanced identification characterization techniques, structure-activity relationship, improvement extraction purification, cellular molecular mechanisms, specific health applications preventing managing conditions with microbiota, commercial nutraceuticals. Short-chain fatty acids reactive sulfur species are gut-derived metabolites that metabolic function by modulating immune system. This review highlights influence food oxidants PBAP-induced modulation Moreover, PBAP challenges application will discussed.
Язык: Английский
Процитировано
0
International Journal of Biological Macromolecules, Год журнала: 2024, Номер 264, С. 130548 - 130548
Опубликована: Фев. 29, 2024
Язык: Английский
Процитировано
4
Journal of Agricultural and Food Chemistry, Год журнала: 2024, Номер 72(22), С. 12398 - 12414
Опубликована: Май 27, 2024
Plant-based peptides (PBPs) benefit functional food development and environmental sustainability. Proteolysis remains the primary method of peptide production because it is a mild nontoxic technique. However, potential safety concerns still emanate from toxic or allergenic sequences, amino acid racemization, iso-peptide bond formation, Maillard reaction, dose usage, frequency. The main aim this review to investigate techno-functions PBPs in matrices, as well their concerns. distinctive characteristics exhibit for improving quality functionality by contributing several crucial formulations processing. include solubility, hydrophobicity, bitterness, foaming, oil-binding, water-holding capacities, which subsequently affect matrices. foodstuff containing depend on proper source plant proteins, selection processing approaches, compliance with legal regulations allergen labeling evaluations. allergenicity toxicity were discussed. conclusion that technologists must apply safe limits consider components generated during products PBPs. Therefore, can be promising strategy provide consumers wholesome health benefits.
Язык: Английский
Процитировано
4
Food Chemistry X, Год журнала: 2024, Номер 24, С. 101873 - 101873
Опубликована: Окт. 3, 2024
Язык: Английский
Процитировано
4
BIO Web of Conferences, Год журнала: 2025, Номер 158, С. 03021 - 03021
Опубликована: Янв. 1, 2025
Several bacteria are found to be potential as antagonists due their capacity in producing extracellular enzymes amylase, protease, gelatinase, cellulose and chitinase. In this research, we collected from both healthy anthracnose-infecting chili plants (root, stem leaf). The results revealed that 27 bacterial isolates non-pathogenic non-hemolytic plants, which 10 isolated roots, 8 leaves, 7 stems 2 fruits. Morphology identification showed most of circular, irregular punctiform, with elevation flat, raised umbonate. White milky dominant, varied opacity (transparent, translucent opaque) textures (slimy, mucoid, shiny dry). Enzymatic activity test 11 produced amylase chitinase (isolates 11, 34, 42, 48, 111,118, 139, 188, 215, 216 218).
Язык: Английский
Процитировано
0
Pharmaceutics, Год журнала: 2025, Номер 17(4), С. 397 - 397
Опубликована: Март 21, 2025
Peptide and protein (PP) therapeutics are highly specific potent biomolecules that treat chronic complex diseases. However, their oral delivery is significantly hindered by enzymatic degradation, instability, poor permeability through the gastrointestinal (GI) epithelium, resulting in low bioavailability. Various strategies have emerged as transformative solutions to address existing challenges, offering enhanced protection, stabilization, absorption of PPs. These primarily focus on two major challenges: protecting PP against harsh conditions enhancing permeation across intestinal membrane. Innovative approaches such pH modulation incorporation enzyme inhibitors usually used mitigate proteolytic degradation during transit GI tract. In a similar vein, enhancers prodrug facilitate epithelial transport, while targeted systems areas tract enhance absorption. Likewise, mucus-penetrating mucoadhesive retention interaction with cells, effectively overcoming barriers like mucus layer tight junctions. Furthermore, structural modifications lipidation, peptide cyclization, polyethylene glycosylation promising alternatives render stability, prolong circulation time, membrane permeability. particular, functional biomaterials, active targeting, lymphatic transport provided new platforms for delivery. Advancing materials science, nanotechnology, disruption medical devices holds frontiers overcome barriers. Despite substantial advancements, limited success clinical translation underscores urgency innovative strategies. This review presents PPs platform, highlighting key transform therapeutic landscapes.
Язык: Английский
Процитировано
0
Intelligent Pharmacy, Год журнала: 2024, Номер 2(4), С. 467 - 484
Опубликована: Май 28, 2024
The increasing quest for therapeutic alternatives in treating non-communicable chronic diseases like obesity has propelled research into bioactive peptides, with a particular focus on milk due to its rich protein composition and associated health benefits. Milk fermentation, traditional process dairy production, enhances the bioactivity of broadening their potential uses. This study investigated anti-obesity peptides from bovine fermented by Lacticaseibacillus casei LBC 237, identifying 143 notably LGPV EVPMP. In silico analyses revealed that EVPMP biopeptides exhibited significant interactions target proteins, employing various molecular such as Van der Waals forces, hydrogen bonds, electrostatic interactions. These shared common binding sites some enzymes, suggesting similar mode interaction between molecule protein, akin key pharmaceuticals recommended these pathologies. Furthermore, amino acid characteristics present including hydrophobic residues Leucine, Glutamate, Valine, Proline, proved essential inhibitory activities. findings highlight agents managing metabolic disorders. They provide important insights mechanisms action, paving way future apply them practically preventing conditions.
Язык: Английский
Процитировано
3