High live birth rates after laparoscopic isthmocele repair in infertility: a systematic review and meta-analysis

Frontiers in Endocrinology, Год журнала: 2025, Номер 16

Опубликована: Апрель 15, 2025

Background Cesarean sections are becoming more common worldwide. One of the long-term complications cesarean section is a scar defect or isthmocele. The presence isthmocele associated with infertility. Objectives This systematic review and meta-analysis examined effect laparoscopic repair on reproductive outcomes patients without Search strategy We searched MEDLINE, EMBASE, Cochrane CENTRAL databases in April 2024. Selection criteria study included cohort studies, case-control case series reporting after among women diagnosed Data collection analysis rates live birth, pregnancy, miscarriage. Main results search identified 866 records 17 articles were included. Clinical pregnancy resection 62% (95% confidence interval (CI) 54-69%) infertility, compared to 33% CI: 16-57%) infertility 36% unknown fertility status (36%, 95% 21–55%). Live birth 72% 54–85%) those 78% 46–94%) 61% 42–77%) status. Women had low miscarriage 10% 6–16%) 7% 3–18%), respectively. prevalence co-existing endometriosis was 29% 22–37%). statistical heterogeneity studies ranged from 0 86%. Conclusions Laparoscopic has demonstrated potential improve outcomes, specifically cases where linked isthmocele-related factors, such as challenges during embryo transfer impaired implantation. However, further well-designed multicenter trials must confirm these findings provide stronger evidence. Systematic registration https://www.crd.york.ac.uk/prospero/ , identifier (CRD42024548864).

Язык: Английский

Uterine scar after caesarean section: principles of healing and evaluation criteria

V F Snegirev Archives of Obstetrics and Gynecology, Год журнала: 2024, Номер unknown

Опубликована: Дек. 12, 2024

The result of a cesarean section (CS) is the formation scar tissue in uterus. inadequate healing and subsequent development incompetent uterus following CS common complication, which can manifest as abnormal uterine bleeding, painful menstruation, secondary infertility. In pregnant women, presence defect be associated with life-threatening complications. For example, rupture during any stage pregnancy or ingrowth placenta into occur. Due to potentially dangerous consequences on wall, several studies have been conducted over past few years, examining risk factors pathophysiological basis for defect. Additionally, diagnostic methods also investigated. At present, there lack clear understanding regarding process behind well unambiguous guidelines certain aspects assessment caesarean section.

Язык: Английский

Delivery mode and risk of intraventricular hemorrhage: A retrospective single-center study on 1760 preterm infants of less than 32 weeks

European Journal of Obstetrics & Gynecology and Reproductive Biology, Год журнала: 2024, Номер 305, С. 147 - 152

Опубликована: Дек. 13, 2024

Язык: Английский