Nanosheet-shaped WS2/ICG nanocomposite for photodynamic/photothermal synergistic bacterial clearance and cutaneous regeneration on infectious wounds
Biomaterials Advances,
Год журнала:
2025,
Номер
169, С. 214192 - 214192
Опубликована: Янв. 18, 2025
Язык: Английский
Electrospun L-Lysine/Amorphous Calcium Phosphate Loaded Core-Sheath Nanofibers for Managing Oral Biofilm Infections and Promoting Periodontal Tissue Repairment
International Journal of Nanomedicine,
Год журнала:
2024,
Номер
Volume 19, С. 2917 - 2938
Опубликована: Март 1, 2024
Introduction:
Periodontitis,
a
chronic
inflammatory
disease
prevalent
worldwide,
is
primarily
treated
through
GTR
for
tissue
regeneration.
The
efficacy
of
GTR,
however,
remains
uncertain
due
to
potential
infections
and
the
intricate
microenvironment
periodontal
tissue.
Herein,
We
developed
novel
core-shell
structure
multifunctional
membrane
using
dual-drug-loaded
coaxial
electrospinning
technique
(Lys/ACP-CNF),
contains
L-lysine
in
outer
layer
aid
controlling
biofilms
after
regenerative
surgery,
ACP
inner
enhance
osteogenic
performance
accelerating
alveolar
bone
repair.
Methods:
biocompatibility
cell
adhesion
were
evaluated
CCK-8
fluorescence
imaging,
respectively.
antibacterial
activity
was
assessed
plate
counting
assay.
ALP,
ARS,
RT-qPCR
used
examine
differentiation.
Additionally,
an
vivo
experiment
conducted
on
rat
model
with
acute
defect
infection.
Micro-CT
histological
analysis
utilized
analyze
Results:
Structural
physicochemical
characterization
confirmed
successful
construction
fibrous
structure.
Lys/ACP-CNF
showed
strong
coaggregation
effects
induced
differentiation
PDLSCs
vitro.
that
promotes
new
formation.
Conclusion:
rapidly
exhibited
excellent
activity,
protected
from
infection,
conducive
osteogenesis,
demonstrating
its
application
clinical
surgery.
Keywords:
anti-microbial
therapy,
L-lysine,
electrospun
membrane,
osteogenic,
regeneration
Язык: Английский
Selection of biofilm-inhibiting ssDNA aptamers against antibiotic-resistant Edwardsiella tarda by inhibition-SELEX and interaction with their binding proteins
Yunting Fan,
Jiang Zheng,
Ying Tan
и другие.
International Journal of Biological Macromolecules,
Год журнала:
2025,
Номер
unknown, С. 140041 - 140041
Опубликована: Янв. 1, 2025
Язык: Английский
Bismuth oxybromide nanosheets accelerating healing of infected wounds at movable part through self-motion promoted piezo- and near infrared light activated photo-performance
Materials Today Chemistry,
Год журнала:
2025,
Номер
45, С. 102639 - 102639
Опубликована: Март 15, 2025
Язык: Английский
BODIPY-based nanoparticles for highly efficient photothermal/gas synergistic therapy against drug-resistant bacterial infection
Journal of Materials Science,
Год журнала:
2024,
Номер
59(41), С. 19628 - 19641
Опубликована: Окт. 24, 2024
Язык: Английский
Quaternized Silk Fibroin Nanocarriers Loaded with Chlorin e6 for Photodynamic Elimination of Drug-Resistant Bacteria and Biofilms
ACS Applied Nano Materials,
Год журнала:
2024,
Номер
7(10), С. 12072 - 12082
Опубликована: Май 3, 2024
The
increasing
prevalence
of
multidrug-resistant
(MDR)
bacteria
primarily
due
to
the
emergence
drug-resistant
biofilms
that
have
rendered
current
antimicrobial
agents
ineffective
poses
a
significant
concern
in
public
health.
Therefore,
innovative
need
be
urgently
developed.
This
study
aimed
design
photodynamic
nanocomposite
(Ce6/HSF)
based
on
chitosan
quaternary
ammonium
salt
(HTCC)-functionalized
silk
fibroin
(SF)
loaded
with
chlorin
e6
(Ce6)
for
eliminating
and
bacteria.
prepared
Ce6/HSF
had
low
toxicity,
good
biocompatibility,
excellent
ability
generate
single-linear-state
oxygen.
In
addition,
can
enter
by
electrostatic
adsorption
its
small
size
cationic
nature.
Furthermore,
it
effectively
promoted
wound
healing
mice
infected
MDR
Staphylococcus
aureus.
Язык: Английский
Recent Developments in Photothermal Therapy: A Bibliometric and Visual Analysis
Опубликована: Янв. 1, 2024
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Язык: Английский
Recent developments in photothermal therapy: a bibliometric and visual analysis
Journal of Biomaterials Science Polymer Edition,
Год журнала:
2024,
Номер
unknown, С. 1 - 21
Опубликована: Дек. 8, 2024
Photothermal
therapy
(PTT)
has
recently
garnered
significant
attention
as
a
prominent
noninvasive
treatment
modality
for
broad
spectrum
of
diseases.
Despite
the
increasing
volume
scholarly
output
over
last
20
years,
holistic
synthesis
that
delineates
worldwide
research
trajectories
remains
elusive.
We
undertook
bibliometric
analysis
literature
from
2004
to
2023,
aiming
delineate
prevailing
focal
points
and
illuminate
prospective
avenues.
Research
articles
on
PTT
were
retrieved
Web
Science
Core
Collection.
Using
tools
such
CiteSpace,
VOSviewer,
Bibliometrix,
we
comprehensively
analyzed
visualized
11,184
published
academic
papers.
China
highest
number
publications.
Journals
related
are
primarily
comprised
interdisciplinary
comprehensive
journals.
associated
with
focused
its
antitumor
properties.
Current
areas
in
this
domain
include
synergistic
combination
photodynamic
therapy,
immunological
mechanisms
enhance
therapeutic
efficacy,
integrated
use
nanoenzyme
catalysis,
role
antimicrobial
applications.
This
provides
an
initial
examination
medical
applications
PTT,
offering
insights
into
global
landscape,
key
interest,
emerging
trends,
thereby
serving
valuable
reference
future
studies
field.
Язык: Английский