Impacts of rising temperatures and water acidification on the oxidative status and immune system of aquatic ectothermic vertebrates: A meta-analysis

The Science of The Total Environment, Год журнала: 2023, Номер 868, С. 161580 - 161580

Опубликована: Янв. 13, 2023

Язык: Английский

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A meta-analysis of impacts of immune response and infection on oxidative status in vertebrates

Conservation Physiology, Год журнала: 2022, Номер 10(1)

Опубликована: Янв. 1, 2022

Abstract Inferring from patterns observed in biomedical research, ecoimmunological theory predicts that oxidative stress is a ubiquitous physiological cost contributes to generating variation immune function between individuals or species. This prediction is, however, often challenged by empirical studies testing the relationship response infection and status markers. points out importance of combining ecological immunology ecology further our understanding proximate causes fitness consequences individual health, adaptability natural anthropogenic environmental changes. I reviewed evidence performed phylogenetic meta-analyses changes markers owing either injection an antigen captive free-living vertebrates (141 studies, 1262 effect sizes, 97 species). The dataset was dominated on fish, birds mammals, which provided 95.8% sizes. Both parasite exposure were associated with status. There significant effects taxonomic class experimental environment (captivity vs. wild). In contrast my predictions, age category (young adult), study design (correlational experimental) proxies pace life (clutch size, litter body mass; for mammals only) negligible this dataset. Several methodological aspects (type immunostimulant, laboratory assay, tissue analysed) showed both strength direction effect. My results suggest alterations are widespread consequence across vertebrates. However, work also identified heterogeneity suggests does not necessarily result stress. Finally, identifies caveats might be relevant interpretation comparability application conservation programs.

Язык: Английский

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Windows of opportunity: Ocean warming shapes temperature‐sensitive epigenetic reprogramming and gene expression across gametogenesis and embryogenesis in marine stickleback

Global Change Biology, Год журнала: 2021, Номер 28(1), С. 54 - 71

Опубликована: Окт. 20, 2021

Rapid climate change is placing many marine species at risk of local extinction. Recent studies show that epigenetic mechanisms (e.g. DNA methylation, histone modifications) can facilitate both within and transgenerational plasticity to cope with changing environments. However, reprogramming (erasure re-establishment marks) during gamete early embryo development may hinder inheritance. Most our knowledge about stems from mammals model organisms, whereas the prevalence extent among non-model wild populations rarely investigated. Moreover, whether dynamics are sensitive environmental conditions not well known, representing a key gap in pursuit identify underlying links between parental exposure patterns environmentally adapted offspring phenotypes. Here, we investigated (DNA methylation/hydroxymethylation) gene expression across gametogenesis embryogenesis stickleback (Gasterosteus aculeatus) under three ocean warming scenarios (ambient, +1.5 +4°C). We found acclimation led dynamic temperature-sensitive throughout development. Both global methylation/hydroxymethylation genes involved modifications were strongly differentially affected by increased scenarios. Comparing transcriptomic profiles gonads, mature gametes embryonic stages showed sex-specific accumulation temperature sensitivity several actors. methyltransferase induction was primarily maternally inherited (suggesting maternal control remethylation), histone-modifying enzymes shaped parents. Importantly, massive, temperature-specific changes landscape occurred blastula, critical stage for successful development, which could, thus, translate substantial consequences phenotype resilience In summary, study identified regulation, reflecting potential 'windows opportunity' adaptive responses future change.

Язык: Английский

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Telomeres and anthropogenic disturbances in wildlife: A systematic review and meta‐analysis

Molecular Ecology, Год журнала: 2022, Номер 31(23), С. 6018 - 6039

Опубликована: Янв. 26, 2022

Abstract Human‐driven environmental changes are affecting wildlife across the globe. These challenges do not influence species or populations to same extent and therefore a comprehensive evaluation of organismal health is needed determine their ultimate impact. Evidence suggests that telomeres (the terminal chromosomal regions) sensitive conditions have been posited as surrogate for animal fitness. Evaluation use in an applied ecological context still scarce. Here, using information from molecular occupational biomedical studies, we aim provide ecologists evolutionary biologists with accessible synthesis links between human disturbances telomere length. In addition, perform systematic review meta‐analysis on studies measuring length wild/wild‐derived animals facing anthropogenic disturbances. Despite relatively small number date, our revealed significant negative association (−0.092 [−0.153, −0.031]; n = 28; k 159). Yet, biomarker understand impact limited. We propose some research avenues will help broadly evaluate suitability: (i) further causal link telomeres; (ii) investigating implications, terms fitness performance, given anthropogenically disturbed scenarios; (iii) better understanding underlying mechanisms dynamics. Future these facets ultimately role markers

Язык: Английский

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Climate change can impair bacterial pathogen defences in sablefish via hypoxia-mediated effects on adaptive immunity

Developmental & Comparative Immunology, Год журнала: 2024, Номер 156, С. 105161 - 105161

Опубликована: Март 21, 2024

Язык: Английский

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Participatory surveillance reveals marsh deer mortality event during an extraordinary flood in Ibera Wetlands, Argentina

Ecosphere, Год журнала: 2025, Номер 16(2)

Опубликована: Фев. 1, 2025

Abstract Mortality events of marsh deer ( Blastocerus dichotomus ) have been historically described in the southern margins its geographical range. Few documented cases show how environmental changes and pathogens interact to trigger mortality scenarios reveal their causes. Here, using a participatory surveillance framework, we document most extensive event observed last three decades occurring Ibera ecoregion, Corrientes, Argentina. Local stakeholders monitored disease or mortality, upon detection, emergency response teams conducted field studies, documenting 409 dead between May August 2017. Complete postmortem examinations were performed on 16 deer, revealing hepatic fibrosis associates with Fasciola hepatica multiple parasite infestations different tissues. Molecular analysis samples from 82 identified parasitic vector‐borne microorganisms, including Anaplasma marginale , Theileria cervi Trypanosoma spp. High‐tick burden significantly associated deficient body condition. Concurrently, increased precipitation watershed height expanded flooded areas, reduced herbaceous cover indicated by land analysis. Our findings suggest that prolonged flooding played critical role interactions habitat availability, parasites. Environmental stressors likely exacerbated effects infections, highlighting importance integrating monitoring wildlife health assessments. results contribute scientific knowledge provides tools enhance management efforts focused protecting population habitats.

Язык: Английский

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Post‐metamorphic growth partially compensates for the effects of climate‐driven stressors on juvenile frog performance

Ecosphere, Год журнала: 2025, Номер 16(2)

Опубликована: Фев. 1, 2025

Abstract Human‐induced climate change, land use changes, and urbanization are predicted to dramatically impact landscape hydrology, which can have devastating impacts on aquatic organisms. For amphibians that rely environments breed develop, it is essential understand how the larval environment development, condition, performance later in life. Two important of urbanization, changes reduced hydroperiod variable density. Here, we explored density affect morphology, physiology, immune defenses at metamorphosis 35 days post‐metamorphosis frog Rana pipiens . We found high‐density conditions had a large negative development resulted longer periods, likelihood metamorphosis, smaller size shorter femur body length ratio, microbiome species evenness compared with animals developed low‐density conditions. However, from treatment experienced compensatory growth post‐metamorphosis, demonstrating accelerated relative treatments, despite not “catching‐up” size. also observed an increase gut liver than those treatment, as well higher bacterial killing ability, greater jump distances their leg across different temperatures. Finally, metabolic rate was overall but especially test temperatures for under conditions, indicating these may expend more energy response acute temperature changes. While effects change direct post‐metamorphosis; however, might come cost reduce ability cope further environmental such increased

Язык: Английский

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Adaptive immunity modulation linked to migratory behaviour in two partially migratory hoopoe Upupa epops populations

Journal of Avian Biology, Год журнала: 2025, Номер 2025(2)

Опубликована: Март 1, 2025

Ecophysiology has enhanced our understanding of avian migration, yet many aspects how these processes interrelate are still unclear. Partially migratory populations provide an ideal framework for its study in the wild, since resident and individuals coexist temporarily same area face similar selection pressures. We focused on two Iberian Eurasian hoopoe Upupa epops , a trans‐Saharan long‐distance migrant, to explore links between immune system behaviour. determined status individual hoopoes using stable isotope analysis deuterium ( 2 H) measured number immunological parameters, including estimates innate adaptive immunity, as well body condition, muscle fat stores. Our results indicate that had higher IgY levels stores compared migrants during breeding season. Moreover, we found seasonal variation leukocyte profiles birds, with heterophil/lymphocyte (H/L) ratios winter than observed significantly H/L complement activity males females, but not within birds. Overall, show differences response linked behaviour partial populations. This contributes unraveling associations physiological ultimately helps understand different strategies maintained partially

Язык: Английский

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Effects of Sample Storage Conditions and Individual Characteristics on Innate Immune Assays in Box Turtles

Journal of Experimental Zoology Part A Ecological and Integrative Physiology, Год журнала: 2025, Номер unknown

Опубликована: Май 19, 2025

ABSTRACT Immune assays are increasingly being used to study immunity in wild animals, with applications ecology, evolution, and conservation. However, the use of immune is hindered by limited taxonomic breadth studies that validate non‐model organisms understanding variables can affect assay results. While freezing blood samples field for later laboratory analysis a common practice, effect storage conditions on viability unclear. In this study, we evaluated plasma (refrigerated or frozen) results two (bacterial killing [BKA] hemagglutination) eastern box turtles ( Terrapene carolina ), declining species threatened disease. We concurrently tested how individual identity phenotypic environmental influenced found 3–17 days produced more repeatable BKA than refrigerating up 3 days, without significantly affecting average performance. performance was reduced after holding frozen 3–4 months. Additionally, there no significant difference hemagglutination between refrigerated samples. Furthermore, males general had higher but lower bacterial ability females. At an level, differences activity, measures were generally correlated each other. Our findings indicate 2 weeks appropriate both T. c. , may extend related species. sex within particular assays, future work should evaluate other

Язык: Английский

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Optomechanical Engineering of Magneto-Responsive Polymers: Enhancing Prosthetic Functionality for Melioidosis and Chytridiomycosis Survivors

Deleted Journal, Год журнала: 2025, Номер unknown

Опубликована: Июнь 5, 2025

Язык: Английский

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