Duration of antibiotic treatment for respiratory tract infections in primary care DOI Creative Commons
Carl Llor, Malene Plejdrup Hansen, Jesper Lykkegaard

и другие.

JAC-Antimicrobial Resistance, Год журнала: 2024, Номер 7(1)

Опубликована: Дек. 26, 2024

Abstract Objectives The primary driver of antimicrobial resistance is excessive antibiotic use, posing a global threat to public health. Reducing individual exposure antibiotics key addressing the problem. This study aimed assess duration courses administered patients with acute respiratory tract infections (RTIs) in care. Methods Consecutive presenting RTI symptoms were prospectively included from general practices and out-of-hours services France, Greece, Lithuania, Poland Spain for two winter periods (February April 2022 2023). Data collected using paper-based Audit Project Odense template, clinicians recording patient age, gender, diagnosis, type prescribed treatment duration. Results A total 196 doctors (133 practice 63 services) registered 11 270 cases, 34.0% (3835) receiving antibiotics. mean course was 7.52 days (SD 2.11), which significantly longer pneumonia, COVID-19 infection pharyngotonsillitis (8.01, 8.00 7.74 days, respectively), lowest predominantly viral infections, such as common cold flu infection, laryngitis bronchitis (6.32, 6.48 6.98 respectively; P < 0.001). 26.7% 10 or longer. Conclusions Antibiotic RTIs are often prolonged, does not align current recommendations Antibiotics should be avoided cases most mixed infections; however, if deemed necessary, substantially reduced minimize unnecessary exposure.

Язык: Английский

Community Pharmacists’ role in Optimising Antibiotic Use: The HAPPY PATIENT Project to Improve Dispensing Practices in Five EU Countries DOI Creative Commons
Maarten Lambert, Ria Benkő, Jesper Lykkegaard

и другие.

Research in Social and Administrative Pharmacy, Год журнала: 2025, Номер unknown

Опубликована: Март 1, 2025

Community pharmacies can play a pivotal role in optimising the use of antibiotics through their dispensing practice. To evaluate impact multifaceted intervention on community pharmacies' quality antibiotic dispensing. A prospective before-after study conducted according to Audit Project Odense methodology France, Greece, Lithuania, Poland, and Spain. Pharmacy staff audited practices self-registry form before after intervention, comprising feedback participants practice, communication training, providing educational materials for patients. Dispensing all oral five days February 2022 interventions 2023 was registered. Data were analysed by country overall using ten indicators, with Chi-square tests Students' t-tests applied. total 91 pharmacists registered 5.054 dispenses. There an 18 % (p < 0.001) improvement mean number safety checks performed 17 reduction dispenses which no intervention. Pharmacists provided more advice patients reduced 35 = 0.006). This came 44 increase inappropriate that provided. Large differences between countries observed. For performing checks, 13 0.004) worsening seen Greece 72 (p=<0.001) In treatment duration dose discussed 97 98 at baseline, respectively, without improvements Spain, this 66 51 significantly improving 80 64 Quality increased significantly, indicating is promising strategy improve use, especially lower practice standards.

Язык: Английский

Процитировано

0

Duration of antibiotic treatment for respiratory tract infections in primary care DOI Creative Commons
Carl Llor, Malene Plejdrup Hansen, Jesper Lykkegaard

и другие.

JAC-Antimicrobial Resistance, Год журнала: 2024, Номер 7(1)

Опубликована: Дек. 26, 2024

Abstract Objectives The primary driver of antimicrobial resistance is excessive antibiotic use, posing a global threat to public health. Reducing individual exposure antibiotics key addressing the problem. This study aimed assess duration courses administered patients with acute respiratory tract infections (RTIs) in care. Methods Consecutive presenting RTI symptoms were prospectively included from general practices and out-of-hours services France, Greece, Lithuania, Poland Spain for two winter periods (February April 2022 2023). Data collected using paper-based Audit Project Odense template, clinicians recording patient age, gender, diagnosis, type prescribed treatment duration. Results A total 196 doctors (133 practice 63 services) registered 11 270 cases, 34.0% (3835) receiving antibiotics. mean course was 7.52 days (SD 2.11), which significantly longer pneumonia, COVID-19 infection pharyngotonsillitis (8.01, 8.00 7.74 days, respectively), lowest predominantly viral infections, such as common cold flu infection, laryngitis bronchitis (6.32, 6.48 6.98 respectively; P &lt; 0.001). 26.7% 10 or longer. Conclusions Antibiotic RTIs are often prolonged, does not align current recommendations Antibiotics should be avoided cases most mixed infections; however, if deemed necessary, substantially reduced minimize unnecessary exposure.

Язык: Английский

Процитировано

1