Diversity of sulfur cycling halophiles within the Salton Sea, California’s largest lake
BMC Microbiology,
Год журнала:
2025,
Номер
25(1)
Опубликована: Март 6, 2025
Microorganisms
are
the
biotic
foundation
for
nutrient
cycling
across
ecosystems,
and
their
assembly
is
often
based
on
availability
of
environment.
Though
previous
research
has
explored
seasonal
lake
turnover
geochemical
within
Salton
Sea,
California's
largest
lake,
microbial
community
this
declining
ecosystem
been
largely
overlooked.
We
collected
seawater
from
a
single
location
Sea
at
0
m,
3
4
5
7
9
10
10.5
m
depths
in
August
2021,
December
April
2022.
observed
that
water
column
microbiome
significantly
varied
by
season
(R2
=
0.59,
P
0.003).
Temperature
0.27,
0.004),
dissolved
organic
matter
0.13,
oxygen
0.089,
0.004)
were
significant
drivers
changes
composition.
In
addition,
several
halophilic
mixotrophs
other
extremotolerant
bacteria
consistently
identified
samples
time
points,
though
relative
abundances
fluctuated
season.
found
while
sulfur
genes
present
all
metagenomes,
coverages
pathway
throughout
column.
Sulfur
oxidation
incomplete
pathways
conserved
seasons.
Our
work
demonstrates
Seawater
capacity
to
metabolize
species
utilize
multiple
trophic
strategies,
such
as
alternating
between
chemorganotrophy
chemolithoautrophy,
survive
harsh,
fluctuating
Together,
these
results
suggest
integral
ever-changing
thus
contributes
dynamics
Sea.
Further
required
understand
how
environmental
implicated
relationship
Sea's
cycle,
dust
proliferation,
respiratory
distress
experienced
local
population.
Язык: Английский
Characterising Measures of Functional Redundancy in, Microbiome Communities via Relative Entropy
Computational and Structural Biotechnology Journal,
Год журнала:
2025,
Номер
27, С. 1482 - 1497
Опубликована: Янв. 1, 2025
Functional
redundancy
has
been
hypothesised
to
be
at
the
core
of
well-evidenced
relation
between
high
ecological
microbiome
diversity
and
human
health.
Here,
we
conceptualise
operationalise
functional
on
a
single-trait
level
for
functionally
annotated
microbial
communities,
utilising
an
information-theoretic
approach
based
relative
entropy
that
also
allows
quantification
interdependency
across
species.
Via
constraint-based
community
modelling
public
faecal
metagenomic
dataset,
demonstrate
strength
species
is
dependent
specific
attributes
function
under
consideration
such
as
rarity
occurring
interdependencies.
Moreover,
by
integrating
metabolome
data,
highlight
measures
have
correlates
in
host's
metabolome.
We
further
microbiomes
sampled
from
colorectal
cancer
patients
display
higher
levels
species-species
interdependencies
than
those
healthy
controls.
By
analysing
models
inflammatory
bowel
disease
(IBD)
study,
show
although
decreased
IBD
subjects,
increased
certain
metabolites,
notably
hydrogen
sulphide.
This
finding
highlights
their
potential
provide
valuable
insights
beyond
diversity.
formalise
concept
communities
its
usefulness
real
providing
foundation
deeper
understanding
how
shapes
capacities
microbiome.
Язык: Английский
The Impact of Antibiotic Therapy on Intestinal Microbiota: Dysbiosis, Antibiotic Resistance, and Restoration Strategies
Antibiotics,
Год журнала:
2025,
Номер
14(4), С. 371 - 371
Опубликована: Апрель 3, 2025
The
human
gut
microbiota—an
intricate
and
dynamic
ecosystem—plays
a
pivotal
role
in
metabolic
regulation,
immune
modulation,
the
maintenance
of
intestinal
barrier
integrity.
Although
antibiotic
therapy
is
indispensable
for
managing
bacterial
infections,
it
profoundly
disrupts
microbial
communities.
Such
dysbiosis
typified
by
diminished
diversity
shifts
community
structure,
especially
among
beneficial
genera
(e.g.,
Bifidobacterium
Eubacterium),
fosters
antibiotic-resistant
strains
horizontal
transfer
resistance
genes.
These
alterations
compromise
colonization
resistance,
increase
permeability,
amplify
susceptibility
to
opportunistic
pathogens
like
Clostridioides
difficile.
Beyond
gastrointestinal
disorders,
emerging
evidence
associates
with
systemic
conditions,
including
chronic
inflammation,
syndrome,
neurodegenerative
diseases,
underscoring
relevance
microbiota–gut–brain
axis.
recovery
pre-existing
communities
post-antibiotic
highly
variable,
influenced
drug
spectrum,
dosage,
treatment
duration.
Innovative
interventions—such
as
fecal
microbiota
transplantation
(FMT),
probiotics,
synbiotics,
precision
microbiome
therapeutics—have
shown
promise
counteracting
mitigating
its
adverse
effects.
therapies
align
closely
stewardship
programs
aimed
at
minimizing
unnecessary
use
preserve
curtail
spread
multidrug-resistant
organisms.
This
review
emphasizes
pressing
need
microbiota-centered
strategies
optimize
administration,
promote
long-term
health
resilience,
alleviate
disease
burden
associated
antibiotic-induced
dysbiosis.
Язык: Английский
Biochar and PGPR Influence Rhizosphere Bacteria and Synergistically Regulate Tomato Seedling Biomass Under Greenhouse Conditions
Journal of soil science and plant nutrition,
Год журнала:
2025,
Номер
unknown
Опубликована: Апрель 25, 2025
Язык: Английский
The Future of Pathogen Detection in Aquaculture: Miniature Labs, Field‐Compatible Assays, environmental DNA and RNA, CRISPR and Metatranscriptomics
Aquaculture Fish and Fisheries,
Год журнала:
2025,
Номер
5(3)
Опубликована: Май 5, 2025
ABSTRACT
Inland
recirculating
aquaculture
is
a
thriving
food
industry
providing
sustainable
and
locally
sourced
high‐quality
protein.
However,
its
expansion
accompanied
by
emerging
challenges
regarding
the
spread
of
pathogens
diseases.
Detection
management
in
remain
underdeveloped
compared
to
other
animal
farming
sectors
due
vast
diversity
species
involved,
non‐domesticated
limited
knowledge
pathogens,
host
responses
disease
mechanisms.
Furthermore,
systems
are
heavily
dependent
on
beneficial
bacterial
communities
for
waste
product
removal
water
quality
maintenance,
with
opportunistic
constituting
an
inherent
component
these
microbial
communities.
To
enhance
potential
inland
as
source
protein,
it
imperative
adopt
advanced
tools
pathogen
detection
monitoring
assessing
overall
health
ecosystem.
This
paper
presents
overview
promising
current
molecular
technological
advancements
that
offer
solutions
system
aquaculture.
We
focus
recently
developed
point‐of‐care
on‐site
methods
using
miniaturized
laboratory
equipment
robust
workflows
operate
independently
cold
chain
logistics.
explore
methodologies
environment
rather
than
through
fish
assessments.
Lastly,
we
discuss
techniques
from
scientific
disciplines
aquaculture,
including
CRISPR‐Cas
protocols
implementation
‘omics’
approaches
comprehensive
characterization
states.
These
demonstrate
considerable
surveillance
and,
subsequently,
early
dynamic
field.
Through
better
understanding
available
options,
managers
scientists
can
collaborate
optimize
systems.
aims
facilitate
communication
between
managers,
equipping
their
facilities.
Язык: Английский