The Power of a Complex Systems Perspective to Elucidate Aging DOI Creative Commons
Alan A. Cohen, Marcel G. M. Olde Rikkert

The Journals of Gerontology Series A, Год журнала: 2024, Номер 79(10)

Опубликована: Сен. 30, 2024

Abstract It is becoming highly accepted that aging, age-related diseases, and geriatric healthcare can move forward if reductionist research complemented by integrative uniting knowledge on specific aging mechanisms, multiple biomedical, social, psychological, lifestyle, environmental factors their interactions. In this special issue, we present exciting papers illustrate how complexity science theory practice be applied to provide a better understanding quantification of healthy vulnerability disease. Recent insights biomarkers, clocks frailty, resilience are covered studied in interaction with dynamic multiscale perspective. The editorial closing viewpoint guide you through basic principles gerontological shed light new horizons, including innovative systems-based interventions.

Язык: Английский

Adopting a complex systems approach to functional ageing: bridging the gap between gerontological theory and empirical research DOI Creative Commons
Almar A. L. Kok, Martijn Huisman, Erik J. Giltay

и другие.

The Lancet Healthy Longevity, Год журнала: 2025, Номер unknown, С. 100673 - 100673

Опубликована: Янв. 1, 2025

Functional ageing, related to but distinct from biological and environmental systems, is defined as the changes in physical, psychological, cognitive, social functioning, well behavioural factors of individuals they age. In this Personal View, we propose that a complex systems perspective functional ageing can show how outcomes such quality life longevity, success prevention treatment, emerge dynamic interactions among these domains, rather than single causes. We support view three ways. First, explain key principles science-namely, resilience, non-linearity, heterogeneity-apply ageing. Second, established gerontological theories geriatric models align with principles. Third, illustrate use novel methodological tools available science for studying Finally, offer glossary concepts recommendations researchers adopt future studies on

Язык: Английский

Процитировано

1

The Power of a Complex Systems Perspective to Elucidate Aging DOI Creative Commons
Alan A. Cohen, Marcel G. M. Olde Rikkert

The Journals of Gerontology Series A, Год журнала: 2024, Номер 79(10)

Опубликована: Сен. 30, 2024

Abstract It is becoming highly accepted that aging, age-related diseases, and geriatric healthcare can move forward if reductionist research complemented by integrative uniting knowledge on specific aging mechanisms, multiple biomedical, social, psychological, lifestyle, environmental factors their interactions. In this special issue, we present exciting papers illustrate how complexity science theory practice be applied to provide a better understanding quantification of healthy vulnerability disease. Recent insights biomarkers, clocks frailty, resilience are covered studied in interaction with dynamic multiscale perspective. The editorial closing viewpoint guide you through basic principles gerontological shed light new horizons, including innovative systems-based interventions.

Язык: Английский

Процитировано

1