Rosa
damascena
Mill,
known
as
Damask
rose,
holds
significance
in
the
Rosaceae
family
due
to
its
aesthetic
appeal,
aromatic
essence,
and
cultural
importance.
The
research
presented
here
investigates
intricate
molecular
processes
that
regulate
growth
of
petals
R.
damascena,
with
a
specific
emphasis
on
activity
nine
genes
linked
production
anthocyanin
enlargement
petals.
Furthermore,
essential
oil
analysis
was
conducted
illuminate
biochemical
composition
underlying
development
rose
quantification
content
revealed
dynamic
changes
throughout
different
stages
petal
development.
Essential
unveiled
elevated
concentrations
crucial
constituents,
including
β-citronellol
geraniol,
within
Aligudarz
genotype
during
OF_PP
stage.
These
results
parallel
observed
higher
same
stages,
underscoring
consistent
association
between
compositions
developmental
damascena.
Through
gene
expression
analysis,
it
key
biosynthesis
such
CHS
CHI
were
upregulated
pigmentation
(stage
3),
while
F3H
F3'H
exhibited
differential
levels
stage
2,
indicating
their
involvement
determining
earlier
patterns
DFR
FLS
explored,
revealing
competing
roles
regulating
branches
flavonoid
pathways.
Additionally,
study
demonstrated
variations
accumulation
genotypes,
suggesting
presence
genetic
diversity
findings
offer
insights
for
enhancing
ornamental
traits
pigment
roses
through
studies
breeding
programs.
Moreover,
they
contribute
deeper
understanding
mechanisms
driving
Seagrasses
maintain
cellular
water
balance
by
regulating
ion
concentrations
and
accumulating
organic
osmolytes,
enabling
them
to
survive
in
the
fluctuating
salinity
of
intertidal
environments.
However,
molecular
mechanisms
underlying
seagrass
responses
changes
remain
relatively
understudied.
To
address
this,
we
conducted
a
multi-omics
analysis
Ruppia
sinensis
under
low,
moderate,
high
conditions
uncover
behind
its
adaptation
fluctuations.
Our
research
revealed
that
transition
from
low
significantly
altered
physiological
characteristics
R.
sinensis.
Simultaneously,
species
enhanced
ability
cope
with
adapt
fluctuations
increasing
antioxidant
enzyme
activity.
Integration
data
further
indicated
conditions,
synthesizes
more
flavonoids
bolster
adaptive
capacity.
Additionally,
phenylpropanoid
metabolic
pathway
appears
play
crucial
role
response
salinity.
Biomedicines,
Год журнала:
2025,
Номер
13(2), С. 470 - 470
Опубликована: Фев. 14, 2025
Tyrosine
kinase
inhibitors
(TKIs)
have
transformed
the
treatment
of
epidermal
growth
factor
receptor
(EGFR)-mutant
non-small
cell
lung
cancer.
However,
resistance
remains
a
major
challenge
in
clinical
practice.
The
tumor
microenvironment
(TME)
is
complex
system
composed
cells,
immune
and
non-immune
non-cellular
components.
Evidence
indicates
that
dynamic
changes
TME
during
TKI
are
associated
with
development
resistance.
Research
has
focused
on
identifying
how
each
component
interacts
tumors
TKIs
to
understand
therapeutic
targets
could
address
In
this
review,
we
describe
components,
such
as
fibroblasts,
blood
vessels,
checkpoint
proteins,
cytokines,
interact
EGFR-mutant
they
can
promote
TKIs.
Furthermore,
discuss
potential
strategies
targeting
novel
approach.
Nitrogen
(N)
is
crucial
for
plant
growth
and
distributed
across
various
N
morphologies
within
organs.
However,
the
mechanisms
controlling
distribution
of
these
are
not
fully
understood.
This
study
investigated
key
amino
acid
(AA)
biosynthesis
pathways
regulating
their
impact
on
physiology
growth.
We
examined
in
leaves,
stems,
roots
two
tobacco
cultivars
(Hongda
K326)
under
different
treatments
at
75,
100
days
after
transplanting
(DAT).
Transcriptome
analysis
was
performed
75
DAT
to
explore
AA
metabolism
pathways.
Weighted
gene
co-expression
network
(WGCNA)
identified
distribution,
Mantel
test
assessed
treatments,
stages,
distribution.
Statistically
significant
differences
were
observed
environmental
conditions,
cultivars,
organs
(p
<
0.05).
WGCNA
phenylalanine
(ko00360),
alanine,
aspartate,
glutamate
(ko00250),
glycine,
serine,
threonine
(ko00260)
Nin-SDS
(sodium
dodecyl
sulfate
insoluble
N),
NW
(water
soluble
NS
respectively.
Increased
application
promoted
accumulation,
while
earlier
stages
cultivar
Hongda
favored
inhibited
high
conditions.
Gene
expression
correlated
with
biomass,
accumulation.
elucidates
tobacco,
emphasizing
role
These
findings
essential
improving
utilization
optimizing
management
practices,
ultimately
enhancing
crop
productivity
supporting
sustainable
agricultural
practices.
International Journal of Molecular Sciences,
Год журнала:
2025,
Номер
26(7), С. 3425 - 3425
Опубликована: Апрель 6, 2025
Cultivated
lettuce
(Lactuca
sativa
L.)
is
considered
one
of
the
most
important
economic
vegetables
worldwide;
however,
it
subjected
to
different
stresses
(salt
stress,
etc.)
during
its
growth
and
development,
resulting
in
yield
reductions.
In
this
study,
we
selected
cultivated
red
wild
species
serriola
investigate
phenotypic
physiological
changes
these
under
salt
treatment
conditions.
Functional
annotation
enrichment
analysis
differentially
expressed
genes
(DEGs)
leaves
roots
between
control
treatments
were
performed,
identifying
key
responding
stress.
The
results
showed
that
two
types
was
limited
by
with
decreased
leaf
area,
main
root
length,
biomass,
photosynthesis
parameters
noted.
exhibited
similar
trends
terms
variation
their
antioxidant
enzymatic
activity
content
osmoregulatory
compounds
leaves.
our
transcriptomic
revealed
mitogen-activated
protein
kinase
(MAPK)
signaling
pathway,
transporters,
cytochrome
P450,
phenylpropanoid
biosynthesis,
isoflavonoid
biosynthesis
involved
response
stress
seedlings.
cultivar
a
greater
abundance
DEGs
related
secondary
metabolite
aquaporins
treatment,
salinity-tolerant
capacity
comparable
species.
These
reveal
pathways
may
play
role
tolerance
seedlings
provide
candidate
could
be
functionally
characterized
further
utilized
genetically
improve
new
salt-tolerant
varieties.
Plants,
Год журнала:
2024,
Номер
13(21), С. 3018 - 3018
Опубликована: Окт. 28, 2024
The
continuous
global
escalation
of
soil
salinization
areas
presents
severe
challenges
to
the
stability
and
growth
agricultural
development
across
world.
In-depth
research
on
sugar
beet
(Beta
vulgaris
L.),
an
important
economic
crop
with
salt
tolerance
characteristics,
is
crucial
for
determine
its
salt-tolerance
mechanisms,
which
has
practical
implications
production.
This
review
summarizes
multifaceted
effects
stress
beet,
ranging
from
individual
plant
responses
cellular
molecular
adaptations.
Sugar
exhibits
robust
including
osmotic
regulation,
ion
balance
management,
compartmentalization
toxic
ions.
Omics
technologies,
genomics,
transcriptomics,
proteomics,
post-translational
modification
omics
metabolomics,
have
played
roles
in
elucidating
these
mechanisms.
Key
genes
pathways
involved
been
identified,
paving
way
targeted
breeding
strategies
biotechnological
advancements.
Understanding
mechanisms
not
only
enhances
our
knowledge
beet’s
adaptation
but
also
provides
insights
improving
other
crops.
Future
studies
should
focus
analyzing
gene
expression
changes
under
gain
insight
into
aspects
Meanwhile,
different
environmental
conditions
be
investigated
improve
their
potential
salinized
soils.
