Associations between Sleep Duration and Autonomic Nervous System Regulation in Patients with Probable Alzheimer’s Disease: A Cross-Sectional Pilot Study
Clocks & Sleep,
Год журнала:
2024,
Номер
6(4), С. 533 - 545
Опубликована: Сен. 24, 2024
In
this
study,
we
aimed
to
investigate
the
relationships
between
sleep
duration
and
autonomic
nervous
system
(ANS)
regulation.
This
cross-sectional
pilot
study
included
27
older
patients
with
probable
Alzheimer’s
disease
who
were
hospitalized
at
a
psychiatric
center.
We
measured
heart
rate
variability
assess
ANS
regulation
night,
evaluated
dementia
severity
via
Clinical
Dementia
Rating
scale,
obtained
data
from
diaries
maintained
by
nurses.
The
analyzed
using
repeated-measures
generalized
linear
models
age,
sex,
severity,
hypertension
status,
medication
use
(antipsychotics)
as
covariates.
A
of
6–9
h
per
night
compared
shorter
than
6
was
associated
greater
increase
in
parasympathetic
activity
(p
=
0.03),
longer
9
decrease
sympathovagal
balance
0.02).
addition,
observed
an
inverted
U-shaped
association
demonstrated
that
may
be
beneficial
for
regulation;
however,
present
involved
only
few
participants
had
some
limitations.
Additional
research
larger
cohort
is
needed
confirm
these
findings.
Язык: Английский
Nighttime phenotype in patients with heart failure: beat-to-beat blood pressure variability predicts prognosis
Hypertension Research,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 17, 2025
Язык: Английский
Circadian Rhythm Disruption and Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis
AJOG Global Reports,
Год журнала:
2025,
Номер
unknown, С. 100479 - 100479
Опубликована: Март 1, 2025
The
aim
of
our
systematic
review
and
meta-analysis
was
to
determine
if
circadian
rhythm
disruption
(CRD)
is
associated
with
polycystic
ovary
syndrome
(PCOS).
Our
objective
pool
the
overall
mean
differences
in
biomarkers
CRD
(including
melatonin
levels,
morning
evening
cortisol
sleep
efficiency)
between
PCOS
patients
controls.
We
hypothesized
that
will
be
more
prominent
PCOS.
A
search
PubMed,
Scopus,
Embase,
ClinicalTrials.Gov,
Cochrane
Database
Systematic
Reviews
conducted
from
inception
until
2024
using
following
MeSH
terms
"circadian
rhythm"
OR
"sleep
disturbance"
"melatonin"
AND
"polycystic
syndrome."
Citation
supplemented
database
search.
Inclusion
criteria
were
women
PCOS,
original
case-control,
cross-sectional,
cohort
studies
identify
parameters
(melatonin,
cortisol,
disturbance).
Exclusion
endocrine
metabolic
co-morbidities,
menopausal
women,
case
reports,
studies,
animal
abstracts,
conference
presentations.
There
no
time
restriction
for
year
publication.
Two
investigators
(T.H.
P.R.)
assessed
quality
included
Newcastle-Ottawa
Scale.
Forest
plots
created
Open
Meta
Analyst
software.
Publication
bias
Egger's
Begg's
tests.
total
16
12
(N=1,100
[531
569
controls]).
Pooled
analysis
showed
difference
levels
controls
14.294
pg/mL,
95%
CI
[6.895,
21.693].
1.103
[-1.058,
3.265],
3.574
[1.741,
5.407],
respectively.
efficiency
scores
-4.059,
[-6.752,
-1.366].
Risk
assessment
NOS
ranged
7
9.
provides
evidence
positively
syndrome.
This
substantiated
by
indicative
disruption,
including
efficiency.
Язык: Английский
Effect of Sleep Duration on Autonomic Nervous System Regulation in Patients with Plausible Alzheimer: A Cross-Sectional Pilot Study
Опубликована: Март 20, 2024
This
study
aimed
to
investigate
the
relationship
between
sleep
duration,
dementia
severity,
age,
and
ANS
regulation.
cross-sectional
pilot
included
27
older
patients
with
probable
Alzheimer’s
disease,
hospitalized
at
a
psychiatric
center.
We
measured
heart
rate
variability
assess
regulation
night,
evaluated
severity
using
Clinical
Dementia
Rating
scale,
obtained
duration
data
from
diaries
maintained
by
nurses.
The
were
analyzed
repeated-measures
generalized
linear
models
sex,
medication
(antipsychotics)
as
covariates.
A
of
7–8
h
per
night
was
associated
better
than
other
durations,
indicated
sympathovagal
balance
(p
=
0.005).
dysregulation
characterized
20.7%
increase
in
sympathetic
nervous
system
activity
14.8%
decrease
parasympathetic
(PSNS)
activity.
found
significant
correlation
PSNS
0.04)
observed
an
inverted
U-shaped
association
demonstrated
that
may
be
critical
maintaining
optimal
Bidirectional
associations
inadequate
aging,
warrant
further
investigation.
Язык: Английский
Long‐term poor sleep quality is associated with adverse donor reactions in college students in Central China: A population‐based cross‐sectional study
Songqing Ke,
Pu Xu,
Jing Xiong
и другие.
Vox Sanguinis,
Год журнала:
2023,
Номер
118(6), С. 455 - 462
Опубликована: Май 16, 2023
Adverse
donor
reaction
(ADR)
could
adversely
impact
the
recruitment
and
retention
of
blood
donors,
but
evidence
effect
sleep
quality
on
ADR
is
limited
controversial.
The
goal
this
study
was
to
explore
association
between
among
college
students
in
Wuhan.The
student
donors
Wuhan
from
March
May
2022
were
recruited.
Self-compiled
general
information
questionnaire
Pittsburgh
index
(PSQI)
investigated
by
convenience
sampling.
Univariable
multivariable
logistic
regression
analyses
used
estimate
association.Among
1014
participants
included
study,
63
group
951
non-ADR
group.
Compared
with
group,
PSQI
scores
higher
(3.44
±
1.81
vs.
2.78
1.82,
p
<
0.01).
results
analysis
showed
that
after
adjusting
gender,
body
mass
index,
donation
history
other
potential
confounding
factors,
related
occurrence
ADRs
(odds
ratio
=
1.231,
95%
confidence
interval
1.075-1.405),
is,
worse
quality,
more
likely
will
occur.The
long-term
poor
a
risk
factor
for
ADRs.
It
should
be
identified
early
before
reduce
incidence
improve
safety
satisfaction
donors.
Язык: Английский