Environment International, Год журнала: 2024, Номер 195, С. 109214 - 109214
Опубликована: Дек. 17, 2024
Язык: Английский
The Science of The Total Environment, Год журнала: 2025, Номер 985, С. 179668 - 179668
Опубликована: Май 27, 2025
The widespread application of per- and polyfluoroalkyl substances (PFAS) resulted in ubiquitous environmental contamination. Understanding the PFAS tissue distribution mammals humans is crucial for assessment potential health risks. levels eleven were determined by UPLC-MS/MS plasma various tissues wild boar (n = 82) hunted Germany. most prevalent (PFOA, PFNA, PFHxS PFOS) detected all analyzed samples. median level sum (Σ 4PFAS) was highest liver (90.2 μg/kg), followed kidney (9.45 (7.63 μg/L), lung (6.84 heart muscle (2.60 spleen (2.46 skeletal (1.03 μg/kg). Consumption a single portion (125 g) containing Σ 4PFAS would result 36.6-fold exceedance tolerable weekly intake (TWI) EFSA 70 kg-person. accumulation (calculated as tissue/plasma ratio) perfluoroalkyl carboxylic acids with ηpfc 8-13 lung, spleen, increased molecule size, indicating passive mechanisms driven hydrophobicity. In contrast, coefficients scattered, additional involvement chain-length dependent active transport processes. observed PFOS (median ratio 18.0). shortest included study (PFHxA, PFHpA, PFOA, PFBS PFHxS) did not accumulate any tissues, probably due to strong binding blood proteins like serum albumin their relative polarity impeding membrane diffusion.
Язык: Английский
Процитировано
0
Environmental Research, Год журнала: 2025, Номер unknown, С. 121947 - 121947
Опубликована: Май 1, 2025
Язык: Английский
Процитировано
0
JACS Au, Год журнала: 2025, Номер unknown
Опубликована: Июнь 2, 2025
Язык: Английский
Процитировано
0
Water, Год журнала: 2024, Номер 17(1), С. 6 - 6
Опубликована: Дек. 24, 2024
Perfluorinated and polyfluoroalkyl substances (PFASs) have been extensively used in many fields since the 1950s due to their distinctive chemical stability. PFASs are becoming emerging pollutants, they attracted special attention all over world because of environmental persistence, bioaccumulation, potential toxicity. Through bibliometric analysis, this study provides a visual analysis 6055 articles about Web Science database from 2000 2023. Research on can be divided into two stages, 2000–2014 2015–2023, number publications frequency citations increase rapidly latter stage. Studies highly interdisciplinary, mainly focusing cluster ecological environmental, involving science, engineering, toxicology. The authors come 106 countries, with United States China being most productive contributors. However, has relatively low per article. A total 2634 institutions participated studies, USA outstanding. An author cooperation shows that lead publication output research activity. Some Chinese rank among top contributors, but there is need for stronger international cooperation. Keyword clusters burst reveal key areas PFASs, including classification, behavior, health effects, removal methods. This comprehensive perspective offering valuable insights trends serving as critical reference future research, policy development, technological innovation.
Язык: Английский
Процитировано
0
Environment International, Год журнала: 2024, Номер 193, С. 109121 - 109121
Опубликована: Ноя. 1, 2024
Exposure to perfluoroalkyl substances (PFAS) are reported have numerous negative health effects and children especially vulnerable. The aim of this study was investigate whether maternal infant PFAS burden any impact on prenatal postnatal growth, liver lipid parameters in infants at age six months. Data diet growth parameters, as well blood samples were collected from healthy pregnant women week 18 the their months postpartum. analysed for enzymes, lipids PFAS. Maternal carboxylic acids (PFCA) fish dinner ≥ 3 days per pregnancy associated with reduced birth weight increased percent gain first life. Infant PFCA concentrations positively serum alanine aminotransferase total- LDL-cholesterol age. Our data demonstrate that exposure an unfavourable metabolic profile a very young This pattern is concerning it may be linked early conditioning later disease. It vital reduce fertile order prevent development disease next generation.
Язык: Английский
Процитировано
0
Environment International, Год журнала: 2024, Номер 195, С. 109214 - 109214
Опубликована: Дек. 17, 2024
Язык: Английский
Процитировано
0