Journal of Clinical Medicine,
Год журнала:
2023,
Номер
12(4), С. 1273 - 1273
Опубликована: Фев. 6, 2023
Delirium
is
characterized
by
an
acutely
altered
mental
status
accompanied
reductions
in
cognitive
function
and
attention.
septic
patients,
termed
sepsis-associated
delirium
(SAD),
differs
several
specific
aspects
from
the
other
types
of
that
are
typically
encountered
intensive
care
units.
Since
sepsis
both
closely
associated
with
increased
morbidity
mortality,
it
important
to
not
only
prevent
but
also
promptly
diagnose
treat
SAD.
We
herein
reviewed
etiology,
pathogenesis,
risk
factors,
prevention,
diagnosis,
treatment,
prognosis
SAD,
including
coronavirus
disease
2019
(COVID-19)-related
delirium.
itself
worsens
long-term
prognosis,
regarded
as
factor
affecting
outcome
post-intensive
syndrome.
In
COVID-19
difficulties
adequately
implementing
ABCDEF
bundle
(Assess,
prevent,
manage
pain;
Both
spontaneous
awakening
breathing
trials:
Choice
analgesia
sedation;
assess,
manage;
Early
mobility
exercise;
Family
engagement/empowerment)
need
for
social
isolation
issues
require
development
conventional
European Archives of Psychiatry and Clinical Neuroscience,
Год журнала:
2021,
Номер
272(1), С. 139 - 154
Опубликована: Июнь 25, 2021
Recently,
much
attention
has
been
drawn
to
the
importance
of
impact
infectious
disease
on
human
cognition.
Several
theories
have
proposed,
explain
cognitive
decline
following
an
infection
as
well
understand
better
pathogenesis
dementia,
especially
Alzheimer's
disease.
This
article
aims
review
state
art
regarding
knowledge
about
acute
viral
infections
cognition,
laying
a
foundation
explore
possible
followed
coronavirus
2019
(COVID-19).
To
reach
this
goal,
we
conducted
narrative
systematizing
six
current
COVID-19
and
its
Recent
findings
suggest
probable
short-
long-term
impacts
in
even
asymptomatic
individuals,
which
could
be
accounted
for
by
direct
indirect
pathways
brain
dysfunction.
Understanding
scenario
might
help
clinicians
health
leaders
deal
with
wave
neuropsychiatric
issues
that
may
arise
pandemic
other
infections,
alleviate
sequelae
these
around
world.
Frontiers in Neurology,
Год журнала:
2021,
Номер
12
Опубликована: Май 17, 2021
The
coronavirus
disease
19
(COVID-19)
can
cause
neurological,
psychiatric,
psychological,
and
psychosocial
impairments.
Literature
regarding
cognitive
impact
of
COVID-19
is
still
limited.
aim
this
study
was
to
evaluate
deficits
emotional
distress
among
post–COVID-19
patients
who
required
functional
rehabilitation.
Specifically,
explored
compared
psychological
status
in
the
subacute
phase
(COVID-19
group)
postillness
period
(post–COVID-19
group).
Forty
admitted
rehabilitation
units
were
enrolled
divided
into
two
groups
according
disease:
(a)
group
(
n
=
20)
(b)
20).
All
underwent
a
neuropsychological
assessment
including
Mini-Mental
State
Evaluation
(MMSE),
Montreal
Cognitive
Assessment
(MoCA),
Hamilton
Rating
Scale
for
Depression,
Impact
Event
Scale–Revised
(IES-R).
A
larger
part
COVID
showed
total
MMSE
(35%)
post-COVID
(5%),
whereas
majority
both
(75–70%)
reported
impairments
MoCA.
significantly
higher
score
subtests
language
p
0.02)
MoCA
executive
functions
0.05),
0.01),
abstraction
group.
Regarding
disturbances,
~40%
presented
with
mild
moderate
depression
(57.9–60%).
levels
at
IES-R
0.02).
These
findings
highlight
gravity
symptoms
that
be
induced
by
infection
need
tailored
rehabilitation,
training
support.
PLoS ONE,
Год журнала:
2021,
Номер
16(3), С. e0248824 - e0248824
Опубликована: Март 31, 2021
Objective
To
characterize
the
functional
impairments
of
a
cohort
patients
undergoing
inpatient
rehabilitation
after
surviving
severe
COVID-19
illness,
in
order
to
better
understand
ongoing
needs
this
patient
population.
Methods
This
study
consisted
retrospective
chart
review
consecutive
hospitalized
for
and
admitted
regional
hospital
from
April
29
th
May
22
nd
,
2020.
Patient
demographics,
clinical
characteristics
complications
acute
hospitalization
were
examined.
Measures
fall
risk
(Berg
Balance
Scale),
endurance
(6
Minute
Walk
Test),
gait
speed
(10
Meter
mobility
(transfer
ambulation
independence),
cognition,
speech
swallowing
(American
Speech
Hearing
Association
National
Outcomes
Measurement
System
Functional
Communication
Measures)
assessed
at
admission
discharge.
Results
The
population
included
was
70%
male,
58.6%
white
with
mean
age
59.5.
length
32.2
days
18.7
intubated.
Patients
spent
16.7
90%
discharged
home.
demonstrated
significant
improvement
discharge
measures
risk,
endurance,
speed,
mobility,
swallowing,
(p<
0.05).
At
discharge,
portion
continued
deficits
cognition
(attention
37%;
memory
28%;
problem
solving
28%),
balance
(55%)
(97%).
Conclusion
improved
significantly
all
these
domains
by
However,
number
exhibited
residual
highlighting
post-acute
care
Abstract
Background
Cognitive
impairment
has
emerged
as
a
common
post-acute
sequela
of
coronavirus
disease
2019
(COVID-19).
We
hypothesised
that
cognitive
exists
in
patients
after
COVID-19
and
it
is
most
severe
admitted
to
the
intensive
care
unit
(ICU).
Methods
This
prospective
controlled
cohort
study
213
participants
performed
at
Helsinki
University
Hospital
Helsinki,
Finland,
comprised
three
groups
patients—ICU-treated
(
n
=
72),
ward-treated
49),
home-isolated
44)—with
confirmed
between
March
13
December
31,
2020,
participating
comprehensive
neuropsychological
evaluation
six
months
acute
phase.
Our
included
control
group
with
no
history
48).
Medical
demographic
data
were
collected
from
electronic
patient
records
interviews
carried
out
four
Questionnaires
filled
phase
provided
information
about
change
functioning
observed
by
close
informant,
well
presence
self-reported
depressive
post-traumatic
symptoms.
Results
The
differed
(effect
size
η
2
p
0.065,
0.004)
total
score,
calculated
measures
domains
(attention,
executive
functions,
memory).
Both
ICU-treated
0.011)
0.005)
worse
than
patients.
Among
those
more
12
years
education,
attention
domain
0.021)
or
non-COVID
controls
0.045);
male
patients,
particular,
impaired
functions
0.037).
Conclusions
compared
less
controls,
showed
long-term
impairment.
existed
particularly
for
men,
functions.
Trial
registration
number
:
ClinicalTrials.gov
NCT04864938,
retrospectively
registered
February
9,
2021
Journal of Clinical Medicine,
Год журнала:
2023,
Номер
12(4), С. 1273 - 1273
Опубликована: Фев. 6, 2023
Delirium
is
characterized
by
an
acutely
altered
mental
status
accompanied
reductions
in
cognitive
function
and
attention.
septic
patients,
termed
sepsis-associated
delirium
(SAD),
differs
several
specific
aspects
from
the
other
types
of
that
are
typically
encountered
intensive
care
units.
Since
sepsis
both
closely
associated
with
increased
morbidity
mortality,
it
important
to
not
only
prevent
but
also
promptly
diagnose
treat
SAD.
We
herein
reviewed
etiology,
pathogenesis,
risk
factors,
prevention,
diagnosis,
treatment,
prognosis
SAD,
including
coronavirus
disease
2019
(COVID-19)-related
delirium.
itself
worsens
long-term
prognosis,
regarded
as
factor
affecting
outcome
post-intensive
syndrome.
In
COVID-19
difficulties
adequately
implementing
ABCDEF
bundle
(Assess,
prevent,
manage
pain;
Both
spontaneous
awakening
breathing
trials:
Choice
analgesia
sedation;
assess,
manage;
Early
mobility
exercise;
Family
engagement/empowerment)
need
for
social
isolation
issues
require
development
conventional
