Living Donor Liver Transplantation for Young Biliary Atresia Recipients Is Associated With Improved Outcomes in the Modern Era
Pediatric Transplantation,
Год журнала:
2025,
Номер
29(1)
Опубликована: Янв. 21, 2025
ABSTRACT
Introduction
Biliary
atresia
(BA)
is
the
most
common
indication
for
liver
transplantation
(LT)
in
children.
We
aimed
to
identify
risk
factors
associated
with
survival
young
patients
BA
modern
era.
Methods
performed
a
retrospective
analysis
of
aged
<
2
years
who
received
their
first
isolated
LT
available
data
from
United
Network
Organ
Sharing
database
(01/2013–12/2022).
Factors
included
multivariable
Cox
regression
were
graft
type,
race/ethnicity,
insurance
status,
laboratory
pediatric
end‐stage
disease
(PELD)
score,
history
portal
vein
thrombosis,
and
intensive
care
unit
(ICU)
status.
Results
1226
recipients
included,
whom
501
(40.9%)
deceased
donor
whole
grafts
(DDWG),
425
(34.7%)
technical
variants
(DDTV),
300
(24.5%)
living
(LDLT).
LDLT
more
likely
be
white
(
p
=
0.008)
have
private
0.001).
Multivariable
demonstrated
that
ICU
status
(hazard
ratio
[HR]
3.23,
95%
confidence
interval
[95%
CI]:
1.72–6.08,
0.001)
DDTV
vs.
(HR
3.03,
CI:
1.14–8.04,
0.03)
an
increased
patient
mortality.
loss
1.89,
1.19–3.00,
0.007)
both
DDWG
3.37,
1.65–6.87,
3.47,
1.69–7.14,
LDLT.
Conclusion
improved
years;
however,
socioeconomic
differences
exist
between
non‐LDLT
recipients.
Efforts
promote
early
equitable
referral
centers
offering
are
essential
improving
outcomes
children
BA.
Язык: Английский
How satellite clinics can improve access to liver transplantation
Liver Transplantation,
Год журнала:
2024,
Номер
30(10), С. 1078 - 1081
Опубликована: Июль 23, 2024
Язык: Английский
The African American Transplant Access Program: Mitigating Disparities in Solid Organ Transplantation
NEJM Catalyst,
Год журнала:
2024,
Номер
5(9)
Опубликована: Авг. 21, 2024
Black
Americans
experience
end-stage
kidney
disease
(ESKD)
at
a
disproportionately
higher
rate
than
other
racial
and
ethnic
groups
in
the
United
States.
Kidney
transplantation
provides
best
outcomes
for
patients
with
ESKD.
However,
frequently
have
decreased
access
to
transplantation.
This
article
summarizes
robust
literature
on
disparities
presents
practical
solution
this
complex
issue
by
redesigning
transplant
process
challenged
structural
institutional
barriers.
The
authors
provide
detailed
overview
of
novel
African
American
Transplant
Access
Program
(AATAP)
its
pillars
cultural
congruency,
trust,
health
literacy,
psychosocial
support.
includes
thorough
description
program's
conceptualization,
creating
program,
preliminary
results,
guidance
establish
similarly
culturally
congruent
programs.
Язык: Английский
Renal Disease and Kidney Transplantation in Hispanic American Persons
Kidney360,
Год журнала:
2024,
Номер
5(11), С. 1763 - 1770
Опубликована: Сен. 16, 2024
The
Hispanic
population
of
the
United
States
is
second
largest
racial
or
ethnic
group,
comprising
18.7%
population.
However,
this
incredibly
heterogeneous
differing
in
genetic
traits,
cultural
upbringing,
educational
backgrounds,
and
financial
status.
impact
heterogeneity
on
prevalence
outcomes
renal
disease
kidney
transplantation
understudied
compared
with
non-Hispanic
White
Black
populations.
What
known
appears
to
be
underrecognized.
This
review
aims
critically
assess
current
medical
literature
individuals,
focusing
etiological
factors,
progression,
related
CKD
transplantation.
By
doing
so,
we
aim
underscore
key
areas
for
further
in-depth
investigation.
Язык: Английский
The importance of equity in transplant oncology
Current Opinion in Organ Transplantation,
Год журнала:
2024,
Номер
unknown
Опубликована: Окт. 8, 2024
Transplant
oncology
encompasses
and
utilizes
liver
transplantation
(LT)
in
combination
with
other
aspects
of
cancer
care
to
offer
improved
long-term
outcomes
for
patients
cancer,
but
not
all
have
equal
access
ability
undergo
LT.
Social
determinants
health
may
negatively
impact
a
patient's
receive
liver-related
oncologic
care,
including
This
review
highlights
recent
work
exposing
gaps
LT,
transplant
oncology,
interventions
ameliorate
these
disparities.
Язык: Английский
Readiness for the Next Pandemic: A Nurse Practitioner-Driven COVID-19 Management Model for Kidney Transplant Recipients
Western Journal of Nursing Research,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 16, 2024
Background:
With
the
rise
of
virulent
pathogens,
transplant
community
faces
unprecedented
challenges
in
caring
for
immunocompromised
patients.
Effective
diagnosis,
treatment,
and
follow-up
are
essential,
with
prompt
immunosuppression
adjustment
hospitalization
decompensated
patients
being
critical
survival.
Objective:
Our
study
aimed
to
determine
if
a
nurse
practitioner-driven
care
model
improves
outcomes
kidney
recipients
who
contracted
COVID-19.
Methods:
We
conducted
retrospective
COVID-19
(N
=
101)
from
April
1,
2020
30,
2021.
Patients
were
classified
into
2
groups:
those
presenting
emergency
department
symptoms
diagnosed
followed
by
practitioners.
Nurse
practitioners
monitored
this
second
group
daily
via
telephone
and/or
video
call.
They
provided
symptom
assessment,
adjustment,
health
counseling,
emotional
support.
Results:
identified
as
decompensating
had
admissions
arranged
nearest
hospital
or
our
center.
In
intervention
(n
66),
was
adjusted
more
rapidly
(4.5
days
vs
7
days),
leading
shorter
illness
duration
(17
26
fewer
acute
injuries
(50.0%
68.6%),
lower
readmission
rates
(5.0%
20%),
better
survival
(97.0%
77.1%).
Conclusion:
As
we
have
preventive
treatment
options
COVID-19,
interventions
close
monitoring
demonstrated
may
be
key
achieving
including
graft
patient
strategies
can
applicable
instances
future
outbreaks
pathogens
help
protect
save
lives
within
population.
Язык: Английский