Investigating hemodynamic factors and rupture risk in internal carotid artery aneurysms: A computational and statistical analysis DOI
Tingting Qi,

Li‐Cai Zhao,

Zeshang Guo

и другие.

Physics of Fluids, Год журнала: 2025, Номер 37(3)

Опубликована: Март 1, 2025

This study investigates the role of hemodynamic factors in assessing rupture risk intracranial internal carotid artery saccular aneurysms. A total 24 unruptured and 12 ruptured aneurysms were analyzed using computational fluid dynamics statistical methods to identify meaningful relationships between parameters risk. Key metrics, including maximum, mean, minimum values blood velocity, oscillatory shear index (OSI), statistically compared. The Weibull model was employed evaluate potential connections these aneurysm rupture. spatial distribution mapped on sac surface high-risk regions prone Results revealed that exhibit lower maximum velocity compared ones. Additionally, demonstrated higher OSI values, highlighting a distinct difference profiles. These findings provide valuable insights into biomechanical influencing may inform clinical assessment strategies.

Язык: Английский

A predictive surrogate model based on linear and nonlinear solution manifold reduction in cardiovascular FSI: A comparative study DOI Creative Commons
M. Barzegar Gerdroodbary, Sajad Salavatidezfouli

Computers in Biology and Medicine, Год журнала: 2025, Номер 189, С. 109959 - 109959

Опубликована: Март 5, 2025

This study investigates the fluid-structure interaction (FSI) simulation of abdominal aorta, with a particular focus on hemodynamic alterations induced by aneurysmal deformations. The behavior within aorta is highly dependent geometric characteristics aneurysm, necessitating use patient-specific models to ensure accurate predictions. primary objective this research enhance predictive capability flow and structural indices in complex FSI biomechanical setting under varying physiological conditions, namely rest exercise states. paper presents comparative analysis between two distinct yet promising surrogate models: Proper Orthogonal Decomposition coupled Long Short-Term Memory (POD + LSTM) Convolutional Neural Network combined (CNN LSTM). methodology, model selection, performance are discussed detail, providing insights into efficacy limitations each approach context personalized cardiovascular simulations.

Язык: Английский

Процитировано

2

Impact of aneurysm sac size on the effectiveness of endovascular coiling in patient-specific middle cerebral artery aneurysms: a computational study DOI Creative Commons
Zhichao Yao, Hao Wen

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Март 14, 2025

This study investigates the hemodynamic efficiency of endovascular coiling in treatment patient-specific middle cerebral artery (MCA) aneurysms using computational models both original and scaled-down geometries. Computational fluid dynamic (CFD) is used for blood flow modelling inside aneurysms. The Casson non-Newtonian model employed to simulate dynamics, while a porous condition represents within aneurysm sac. Key factors, including wall shear stress (WSS) oscillatory index (OSI), are analyzed evaluate effectiveness across different sizes. Results indicate that significantly reduces rupture risk, with larger sac volumes demonstrating more pronounced decrease high-risk zones. These findings offer insights into optimizing treatments varying morphologies.

Язык: Английский

Процитировано

0

Investigating hemodynamic factors and rupture risk in internal carotid artery aneurysms: A computational and statistical analysis DOI
Tingting Qi,

Li‐Cai Zhao,

Zeshang Guo

и другие.

Physics of Fluids, Год журнала: 2025, Номер 37(3)

Опубликована: Март 1, 2025

This study investigates the role of hemodynamic factors in assessing rupture risk intracranial internal carotid artery saccular aneurysms. A total 24 unruptured and 12 ruptured aneurysms were analyzed using computational fluid dynamics statistical methods to identify meaningful relationships between parameters risk. Key metrics, including maximum, mean, minimum values blood velocity, oscillatory shear index (OSI), statistically compared. The Weibull model was employed evaluate potential connections these aneurysm rupture. spatial distribution mapped on sac surface high-risk regions prone Results revealed that exhibit lower maximum velocity compared ones. Additionally, demonstrated higher OSI values, highlighting a distinct difference profiles. These findings provide valuable insights into biomechanical influencing may inform clinical assessment strategies.

Язык: Английский

Процитировано

0