How does epigenetics influence the course of evolution?

Philosophical Transactions of the Royal Society B Biological Sciences, Год журнала: 2021, Номер 376(1826), С. 20200111 - 20200111

Опубликована: Апрель 17, 2021

Epigenetics is the study of changes in gene activity that can be transmitted through cell divisions but cannot explained by DNA sequence. Epigenetic mechanisms are central to regulation, phenotypic plasticity, development and preservation genome integrity. often held make a minor contribution evolutionary change because epigenetic states typically erased reset at every generation, therefore, not heritable. Nonetheless, there growing appreciation variation makes direct indirect contributions processes. First, some intergenerationally affect phenotype offspring. Moreover,

Язык: Английский

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Fertilization mode differentially impacts the evolution of vertebrate sperm components

Nature Communications, Год журнала: 2022, Номер 13(1)

Опубликована: Ноя. 10, 2022

Abstract Environmental change frequently drives morphological diversification, including at the cellular level. Transitions in environment where fertilization occurs (i.e., mode) are hypothesized to be a driver of extreme diversity sperm morphology observed animals. Yet how mode impacts evolution components—head, midpiece, and flagellum—each with different functional roles that must act as an integrated unit remains unclear. Here, we test this hypothesis by examining component lengths across 1103 species vertebrates varying (external vs. internal fertilization). Sperm length is explained part vertebrates, but influences varies among components vertebrate clades. We also identify evolutionary responses not influenced mode: midpieces evolve rapidly both external fertilizers. Fertilization thus through complex component- clade-specific responses.

Язык: Английский

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Potential implications of sperm DNA methylation functional properties in aquaculture management

Reviews in Aquaculture, Год журнала: 2022, Номер 15(2), С. 536 - 556

Опубликована: Сен. 3, 2022

Abstract The biology of fish sperm, an important topic in the research reproduction and fisheries from basic science to evolutionary applied aspects, has implications for aquaculture management, breeding biological conservation. quality spermatozoa plays a vital role fertility, directly affects health performance offspring. Environmental factors that affect determinants usually reflected DNA methylation pattern epigenome, which may change offspring's performance. aim present study was conduct review on existing data about as tool identifying offspring based their phenotypes performances. Furthermore, this provides valuable knowledge fundamental sciences dealing with enhancement selection, environmental adaptation. also describes individual parts related fish, including overview methods can be used methylation, dynamics epigenetic inheritance; identification changes sperm function response internal external environment constraints, potential relationships between physiological regulation determinants. Overall, revealed our intergenerational inheritance adaptability through is very limited, no general conclusion could approached literature mostly due non‐standardized experimental protocol or analytical tools.

Язык: Английский

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Shedding light on the impacts of gestational exposure to polystyrene nanoplastics on the reproductive performance of Poecilia reticulata female and on the biochemical response of embryos

Journal of Hazardous Materials, Год журнала: 2021, Номер 427, С. 127873 - 127873

Опубликована: Ноя. 25, 2021

Язык: Английский

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Thermal Performance Curves Are Shaped by Prior Thermal Environment in Early Life

Frontiers in Physiology, Год журнала: 2021, Номер 12

Опубликована: Окт. 20, 2021

Understanding links between thermal performance and environmental variation is necessary to predict organismal responses climate change, remains an ongoing challenge for ectotherms with complex life cycles. Distinct stages can differ in sensitivity, experience different conditions as development unfolds, and, because are by nature interdependent, effects carry over from one stage affect at others. Thermal may therefore respond carryover of prior environments, yet detailed insights into the nature, strength, direction those still lacking. Here, aquatic ectotherm whose early planktonic (gametes, embryos, larvae) govern adult abundances dynamics, we explore environments fertilization embryogenesis on curves end development. We factorially manipulate temperatures embryogenesis, then, each combination temperatures, measure survival (end larval stage) throughout range. By combining generalized linear mixed modeling parametric bootstrapping, formally estimate compare curve descriptors (thermal optima, limits, breadth) among reveal temperature but not fertilization, optima completion Specifically, shifted track during while limits breadth remained unchanged. Our results argue that key aspects shaped environment life, warranting further investigation possible mechanisms underpinning response, closer consideration when predicting change.

Язык: Английский

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Does post-ejaculatory sperm experience prior to fertilization alter offspring performance beyond paternity in an external fertilizing fish?

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Апрель 22, 2024

Abstract Recent research has suggested that the environment encountered by sperm post-ejaculation may impact offspring development beyond transfer of paternal genome. The mechanisms underlie such effects remain unclear, but two non-mutually exclusive processes have been proposed. 1) Haploid selection, whereby stressful conditions act as stronger pre-fertilization selective pressures on semen than under benign situations, resulting in fertilization of, average higher quality and production exhibit superior performance across all environmental they might encounter. 2) Epigenetic inheritance, where induce changes are passed down to offspring, altered gene expression offspring. This would be adaptive if experiences anticipate what is come improve match those conditions. Capelin ( Mallotus villosus ) embryos sensitive salinity represent a good system investigate these phenomena. We used split-ejaculate split-brood experimental block design expose capelin known (25 psu) (35 prior egg contact, split each batch fertilized eggs for incubation at matched mismatched exposure. Our findings revealed no differences hatch characteristics between produced exposed A follow-up experiment found same result with an increased selection gradient 5 psu 35 psu. study does not support hypothesis exert influence characteristics, independent paternity. Instead, our results suggest sole influential factor determining

Язык: Английский

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Timing-specific parental effects of ocean warming in a coral reef fish

Proceedings of the Royal Society B Biological Sciences, Год журнала: 2024, Номер 291(2023)

Опубликована: Май 1, 2024

Population and species persistence in a rapidly warming world will be determined by an organism's ability to acclimate warmer conditions, especially across generations. There is potential for transgenerational acclimation but the importance of ontogenetic timing transmission environmentally induced parental effects remains mostly unknown. We aimed disentangle two critical stages (juvenile development reproduction) new-generation potential, exposing spiny chromis damselfish

Язык: Английский

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Coevolution of longevity and female germline maintenance

Proceedings of the Royal Society B Biological Sciences, Год журнала: 2024, Номер 291(2024)

Опубликована: Июнь 1, 2024

An often-overlooked aspect of life-history optimization is the allocation resources to protect germline and secure safe transmission genetic information. While failure do so renders significant fitness consequences in future generations, maintenance comes with substantial costs. Thus, should trade off other decisions be optimized accordance an organism’s reproductive schedule. Here, we tested this hypothesis by studying lines seed beetle, selected for early (E) or late (L) reproduction 350 240 respectively. Female animals provide screening male gametes their tract oocytes. reveal ability young aged E- L-females form mating them males ejaculates artificially elevated levels protein DNA damage. We find that E-females peaks at age then declines, while opposite true L-females, respective regime. These findings identify central role integrity evolution highlight how females can play a crucial mitigating effects on mutation rate offspring quality.

Язык: Английский

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Heatwave‐Induced Paternal Effects Have Limited Adaptive Benefits in Offspring

Ecology and Evolution, Год журнала: 2024, Номер 14(10)

Опубликована: Окт. 1, 2024

ABSTRACT As the threat of climate change and associated heatwaves grows, we need to understand how natural populations will respond. Inter‐generational non‐genetic inheritance may play a key role in rapid adaptation, but whether such mechanisms are truly adaptive sufficient protect wild is unclear. The contribution paternal effects particular not fully understood, even though male reproductive system be highly sensitive heatwaves. We used zebrafish Danio rerio investigate on fertility assess potential benefits their offspring number large‐scale heatwave experiments. Heatwave conditions had negative by reducing gamete quality fertilisation success, found indications an effect hatching produced heatwave‐exposed males. Our findings highlight importance including female when determining species ability cope with extreme suggest that parental provide limited benefits.

Язык: Английский

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Condition‐dependent seminal fluid gene expression and intergenerational paternal effects on ejaculate quality

Functional Ecology, Год журнала: 2021, Номер 36(4), С. 798 - 811

Опубликована: Дек. 14, 2021

Abstract There is increasing evidence to show that the environment experienced by fathers can have intergenerational paternal effects on phenotype of offspring. Paternal be mediated ejaculate traits beyond genes carried sperm, for example through methylation DNA during spermatogenesis, or non‐sperm components such as small RNAs seminal fluid proteins (sfps). Theory suggests ejaculate‐mediated important evolutionary consequences, especially if they exhibit condition‐dependent expression. Here we use nutritional geometry approach explore condition dependence in and cricket Teleogryllus oceanicus . We fed males one 24 chemically defined diets varied macronutrient concentration ratio protein (P) carbohydrate (C). measured expenditure testes accessory gland growth, expression three sfp are known impact sperm viability survival embryos hatching. also hatching success reproductive phenotypes adult found linear P C mass, correlated two genes. diet had no effect were significant produced sons, but sons fecundity daughters. Our data suggest quality a non‐genetic component determined environment, which holds implications maintenance variation heritable male fitness. A free Plain Language Summary within Supporting Information this article.

Язык: Английский

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