New developments for the Quest for Orthologs benchmark service DOI Creative Commons

Adrian Altenhoff,

Yannis Nevers, Vinh Tran

и другие.

NAR Genomics and Bioinformatics, Год журнала: 2024, Номер 6(4)

Опубликована: Сен. 28, 2024

Abstract The Quest for Orthologs (QfO) orthology benchmark service (https://orthology.benchmarkservice.org) hosts a wide range of standardized benchmarks inference evaluation. It is supported and maintained by the QfO consortium, used to gather ortholog predictions examine strengths weaknesses newly developed existing methods. web server allows different methods be compared in way using same proteome data. results are useful developing new can help researchers guide their choice method applications comparative genomics phylogenetic analysis. We here present release Orthology Benchmark Service with based on feature architecture similarity as well updated reference proteomes. further provide meta-analysis public from 18 assignment reveal how they relate terms performance. These users orthologs best suited purpose.

Язык: Английский

Perspectives on tracking data reuse across biodata resources DOI Creative Commons
Karen Ross, Frederic Bastian, M.H. Buys

и другие.

Bioinformatics Advances, Год журнала: 2024, Номер 4(1)

Опубликована: Янв. 1, 2024

Abstract Motivation Data reuse is a common and vital practice in molecular biology enables the knowledge gathered over recent decades to drive discovery innovation life sciences. Much of this has been collated into databases, such as UniProtKB, these resources derive enormous value from sharing data among themselves. However, quantifying documenting kind remains challenge. Results The article reports on one-day virtual workshop hosted by UniProt Consortium March 2023, attended representatives biodata resources, experts management, NIH program managers. Workshop discussions focused strategies for tracking reuse, best practices reusing data, challenges associated with tracking. Surveys showed that widespread, but critical information reproducibility sometimes lacking. Challenges include costs tensions between open sharing, restrictive licenses, difficulties commercial use. Recommendations emerged discussion include: development standardized formats education about obstacles posed continued recognition funding agencies management activity requires dedicated resources. Availability implementation Summaries survey results are available at: https://docs.google.com/forms/d/1j-VU2ifEKb9C-sW6l3ATB79dgHdRk5v_lESv2hawnso/viewanalytics (survey providers) https://docs.google.com/forms/d/18WbJFutUd7qiZoEzbOytFYXSfWFT61hVce0vjvIwIjk/viewanalytics users).

Язык: Английский

Процитировано

1

New developments for the Quest for Orthologs benchmark service DOI Creative Commons

Adrian Altenhoff,

Yannis Nevers, Vinh Tran

и другие.

NAR Genomics and Bioinformatics, Год журнала: 2024, Номер 6(4)

Опубликована: Сен. 28, 2024

Abstract The Quest for Orthologs (QfO) orthology benchmark service (https://orthology.benchmarkservice.org) hosts a wide range of standardized benchmarks inference evaluation. It is supported and maintained by the QfO consortium, used to gather ortholog predictions examine strengths weaknesses newly developed existing methods. web server allows different methods be compared in way using same proteome data. results are useful developing new can help researchers guide their choice method applications comparative genomics phylogenetic analysis. We here present release Orthology Benchmark Service with based on feature architecture similarity as well updated reference proteomes. further provide meta-analysis public from 18 assignment reveal how they relate terms performance. These users orthologs best suited purpose.

Язык: Английский

Процитировано

0