Variable Presence of an Evolutionarily New Brain Structure is Related to Trait Impulsivity

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Окт. 24, 2024

Abstract Background Impulsivity is a multidimensional construct reflecting poor constraint over one’s behaviors. Clinical psychology research identifies separable impulsivity dimensions that are each unique transdiagnostic indicators for psychopathology. Yet, despite this apparent clinical importance, the shared and neuroanatomical correlates of these factors remain largely unknown. Concomitantly, neuroimaging variably present human brain structures implicated in cognition disorder: folds (sulci) cerebral cortex located latest developing most evolutionarily expanded hominoid-specific association cortices. Methods We tethered two fields to test whether variability one such structure anterior cingulate (ACC)—the paracingulate sulcus (PCGS)—was related individual differences trait impulsivity. 120 adult participants with internalizing or externalizing psychopathology completed magnetic resonance imaging scan Three-Factor Index. Using precision techniques, we manually identified PCGS, when present, acquired quantitative folding metrics (PCGS length ACC local gyrification index). Results Neuroanatomical-behavioral analyses revealed leftward symmetrical PCGS patterns had greater severity Lack Follow Through (LFT)—which captures inattention lack perseverance—than those rightward asymmetry. Neuroanatomical-functional co-localized focal locus found meta-analysis on feature underlying LFT. Both did not relate any dimension. Conclusions This study advances understanding establishes notion topographical organization distinct, cortical expanses underlie robust, implications

Язык: Английский

Variable Presence of an Evolutionarily New Brain Structure is Related to Trait Impulsivity

Biological Psychiatry Cognitive Neuroscience and Neuroimaging, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 1, 2024

Язык: Английский