Monkey lateral prefrontal cortex subregions differentiate between perceptual exposure to visual stimuli DOI Creative Commons

Kyoko Leaman,

Nadira Yusif Rodriguez, Aarit Ahuja

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Июль 29, 2024

Each day, humans must parse visual stimuli with varying amounts of perceptual experience, ranging from incredibly familiar to entirely new. Even when choosing a novel buy at bookstore, one sees covers they have repeatedly experienced intermixed recently released titles. Visual exposure has distinct neural correlates in the lateral prefrontal cortex (LPFC) nonhuman primates. However, it is currently unknown if this function may be localized specific subregions within LPFC. Specifically, we aimed determine whether posterior fundus area 46 (p46f), an that responds deviations learned sequences, also less frequently presented outside sequential context. We compare responses p46f adjacent subregion, ventral (p46v), which propose more likely show exposure-dependent due its proximity novelty responsive regions. To test or p46v represent exposure, performed awake functional magnetic resonance imaging (fMRI) on three male monkeys as observed varied their number daily presentations. Here p46v, but not p46f, shows preferential activation low further localizing effects monkey These results align previous research found LPFC and are consistent proposal performs sequence-specific function. Further, expand our knowledge role localize processing broader brain region.

Язык: Английский

Monkey lateral prefrontal cortex subregions differentiate between perceptual exposure to visual stimuli DOI Creative Commons

Kyoko Leaman,

Nadira Yusif Rodriguez, Aarit Ahuja

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Июль 29, 2024

Each day, humans must parse visual stimuli with varying amounts of perceptual experience, ranging from incredibly familiar to entirely new. Even when choosing a novel buy at bookstore, one sees covers they have repeatedly experienced intermixed recently released titles. Visual exposure has distinct neural correlates in the lateral prefrontal cortex (LPFC) nonhuman primates. However, it is currently unknown if this function may be localized specific subregions within LPFC. Specifically, we aimed determine whether posterior fundus area 46 (p46f), an that responds deviations learned sequences, also less frequently presented outside sequential context. We compare responses p46f adjacent subregion, ventral (p46v), which propose more likely show exposure-dependent due its proximity novelty responsive regions. To test or p46v represent exposure, performed awake functional magnetic resonance imaging (fMRI) on three male monkeys as observed varied their number daily presentations. Here p46v, but not p46f, shows preferential activation low further localizing effects monkey These results align previous research found LPFC and are consistent proposal performs sequence-specific function. Further, expand our knowledge role localize processing broader brain region.

Язык: Английский

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