Serum Spike Protein Persistence Post COVID Is Not Associated with ME/CFS DOI Open Access

Annick Fehrer,

Franziska Sotzny, Laura Kim

и другие.

Journal of Clinical Medicine, Год журнала: 2025, Номер 14(4), С. 1086 - 1086

Опубликована: Фев. 8, 2025

Background/Objectives: According to the World Health Organization (WHO) and Centers for Disease Control Prevention (CDC), an estimated 3–6% of people suffer from post-COVID condition or syndrome (PCS). A subset meets diagnostic criteria myalgic encephalomyelitis/chronic fatigue (ME/CFS). Studies have reported that SARS-CoV-2 proteins RNA can persist after acute infection in serum tissues, but their role PCS is unclear. Methods: Here, spike protein was analyzed 121 patients with predominant exertional intolerance, whom 72 met ME/CFS, 37 recovered healthy controls, 32 pre-pandemic controls. Results: Spike detected 11% 2% patients, 14% ME/CFS between 4 31 months infection, not samples. The occurrence concentration did correlate vaccination timepoints. In presence associated severity symptoms functional disability. 5 out 22 who under-went immunoglobulin depletion, levels were reduced undetectable treatment, indicating binding immunoglobulins. Conclusions: summary, this study identified a found no association ME/CFS.

Язык: Английский

Targeting the SARS-CoV-2 reservoir in long COVID DOI
Amy D. Proal, Soo Aleman, Morgane Bomsel

и другие.

The Lancet Infectious Diseases, Год журнала: 2025, Номер unknown

Опубликована: Фев. 1, 2025

Язык: Английский

Процитировано

1
NIAID workshop on infections and autoimmune diseases DOI

S E Ferguson,

Annette L. Rothermel,

Patricia Rohan

и другие.

Nature Immunology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 24, 2025

Язык: Английский

Процитировано

0
Serum Spike Protein Persistence Post COVID Is Not Associated with ME/CFS DOI Open Access

Annick Fehrer,

Franziska Sotzny, Laura Kim

и другие.

Journal of Clinical Medicine, Год журнала: 2025, Номер 14(4), С. 1086 - 1086

Опубликована: Фев. 8, 2025

Background/Objectives: According to the World Health Organization (WHO) and Centers for Disease Control Prevention (CDC), an estimated 3–6% of people suffer from post-COVID condition or syndrome (PCS). A subset meets diagnostic criteria myalgic encephalomyelitis/chronic fatigue (ME/CFS). Studies have reported that SARS-CoV-2 proteins RNA can persist after acute infection in serum tissues, but their role PCS is unclear. Methods: Here, spike protein was analyzed 121 patients with predominant exertional intolerance, whom 72 met ME/CFS, 37 recovered healthy controls, 32 pre-pandemic controls. Results: Spike detected 11% 2% patients, 14% ME/CFS between 4 31 months infection, not samples. The occurrence concentration did correlate vaccination timepoints. In presence associated severity symptoms functional disability. 5 out 22 who under-went immunoglobulin depletion, levels were reduced undetectable treatment, indicating binding immunoglobulins. Conclusions: summary, this study identified a found no association ME/CFS.

Язык: Английский

Процитировано

0