Potentials of genomics in combating neglected tropical diseases (NDTs) in Africa: a brief review DOI Open Access
Jacob K. P. Kwaga, Daniel Thakuma Tizhe, Israel Ogwuche Ogra

и другие.

EUREKA Life Sciences, Год журнала: 2025, Номер 1, С. 54 - 61

Опубликована: Апрель 24, 2025

Neglected tropical diseases (NTDs) represent a significant global health challenge, affecting over one billion individuals, predominantly in impoverished and sub-tropical regions of the world. These contribute to cycle poverty, ill-health, social exclusion. In recent years, emergence integration genomic technologies into public research has offered new opportunities for understanding dynamics NTDs terms transmission, infection, resistance mechanisms, which turn pave ways monitoring pathogens evolution, diagnostics control strategies that are precise cost-effective. This review examines studies, epidemiology, burden, socio-economic impacts NTDs, particularly within African context. It underscores historical neglect these agendas highlights pressing need enhanced funding, innovative research, collaborative policies combat their prevalence. emphasizes pivotal role genomics advancing disease surveillance, outbreak management, development novel diagnostics, therapeutics, preventive strategies. By leveraging advancements technologies, including whole-genome sequencing CRISPR-based diagnostics. The aims inform targeted interventions foster approach integrates human, animal, environmental health. Furthermore, this analysis explores potential addressing unique challenges posed by ultimately contributing targets set WHO elimination 2030. findings underscore urgent multidisciplinary effectively tackle way substantial improvements outcomes across Africa beyond

Язык: Английский

Potentials of genomics in combating neglected tropical diseases (NDTs) in Africa: a brief review DOI Open Access
Jacob K. P. Kwaga, Daniel Thakuma Tizhe, Israel Ogwuche Ogra

и другие.

EUREKA Life Sciences, Год журнала: 2025, Номер 1, С. 54 - 61

Опубликована: Апрель 24, 2025

Neglected tropical diseases (NTDs) represent a significant global health challenge, affecting over one billion individuals, predominantly in impoverished and sub-tropical regions of the world. These contribute to cycle poverty, ill-health, social exclusion. In recent years, emergence integration genomic technologies into public research has offered new opportunities for understanding dynamics NTDs terms transmission, infection, resistance mechanisms, which turn pave ways monitoring pathogens evolution, diagnostics control strategies that are precise cost-effective. This review examines studies, epidemiology, burden, socio-economic impacts NTDs, particularly within African context. It underscores historical neglect these agendas highlights pressing need enhanced funding, innovative research, collaborative policies combat their prevalence. emphasizes pivotal role genomics advancing disease surveillance, outbreak management, development novel diagnostics, therapeutics, preventive strategies. By leveraging advancements technologies, including whole-genome sequencing CRISPR-based diagnostics. The aims inform targeted interventions foster approach integrates human, animal, environmental health. Furthermore, this analysis explores potential addressing unique challenges posed by ultimately contributing targets set WHO elimination 2030. findings underscore urgent multidisciplinary effectively tackle way substantial improvements outcomes across Africa beyond

Язык: Английский

Процитировано

0