Potential Genetic Markers Associated with Environmental Adaptability in Herbivorous Livestock
Animals,
Год журнала:
2025,
Номер
15(5), С. 748 - 748
Опубликована: Март 5, 2025
Herbivorous
livestock,
such
as
cattle,
sheep,
goats,
horses,
and
donkeys,
play
a
crucial
role
in
agricultural
production
possess
remarkable
resilience
to
extreme
environmental
conditions,
driven
by
complex
genetic
mechanisms.
Recent
advancements
high-throughput
sequencing,
genome
assembly,
data
integration
have
enabled
deeper
understanding
of
the
basis
their
adaptation.
This
review
identifies
key
genes
associated
with
high-altitude,
heat,
cold,
drought
adaptation,
providing
insights
into
molecular
mechanisms
underlying
these
traits.
By
elucidating
adaptations,
our
study
aims
support
conservation
efforts,
inform
selective
breeding
programs,
enhance
productivity,
ultimately
contributing
sustainable
livestock
farming
economic
benefits
for
farmers.
Язык: Английский
Deciphering the Population Characteristics of Leiqiong Cattle Using Whole-Genome Sequencing Data
Animals,
Год журнала:
2025,
Номер
15(3), С. 342 - 342
Опубликована: Янв. 24, 2025
Long-term
geographic
isolation
and
breeding
programs
both
influence
population
characteristics.
Leiqiong
cattle,
a
native
breed
from
the
southernmost
region
of
China,
are
renowned
for
disease
heat
resistance,
with
two
subgroups
on
Hainan
Island
Leizhou
Peninsula.
However,
genomic
differences
between
them
remain
unexplored.
In
this
study,
we
conducted
comparisons
using
whole-genome
sequencing
data
cattle
three
commercial
breeds
to
assess
their
structures.
in
exhibited
lower
genetic
diversity
pure
ancestral
content
due
mainland.
contrast,
subgroup
Guangdong
displayed
higher
mixed
ancestry,
influenced
by
intrusion
breeds.
The
divergence
was
evaluated
estimating
distance
0.08
split
time
3400
4250
years
ago,
highlighting
role
geographical
barriers
speciation.
Notably,
candidate
genes
were
identified
through
selection
sweeps,
including
PIP4K2A,
potentially
related
immunity,
TNFSF4,
possibly
involved
hair
follicle
development.
Our
findings
reveal
different
structures
characteristics
providing
valuable
insights
into
evolutionary
history
establishing
foundation
future
strategies.
Язык: Английский
Leveraging Whole-Genome Resequencing to Uncover Genetic Diversity and Promote Conservation Strategies for Ruminants in Asia
Animals,
Год журнала:
2025,
Номер
15(6), С. 831 - 831
Опубликована: Март 13, 2025
Whole-genome
resequencing
(WGRS)
is
a
critical
branch
of
whole-genome
sequencing
(WGS),
primarily
targeting
species
with
existing
reference
genomes.
By
aligning
data
to
the
genome,
WGRS
enables
precise
detection
genetic
variations
in
individuals
or
populations.
As
core
technology
genomic
research,
WGS
holds
profound
significance
ruminant
studies.
It
not
only
reveals
intricate
structure
genomes
but
also
provides
essential
for
deciphering
gene
function,
variation
patterns,
and
evolutionary
processes,
thereby
advancing
exploration
mechanisms.
However,
still
faces
several
challenges,
such
as
incomplete
inaccurate
genome
assembly,
well
annotation
numerous
unknown
genes
functions.
Although
can
identify
vast
number
variations,
specific
relationships
between
these
phenotypes
often
remain
unclear,
which
limits
its
potential
functional
studies
breeding
applications.
performing
on
multiple
samples,
assembly
challenges
be
effectively
addressed,
particularly
regions
high
repeat
content
complex
structural
variations.
accurately
subtle
among
different
populations
further
elucidate
their
associations
traits,
overcoming
limitations
providing
more
information
research
This
review
systematically
summarizes
latest
applications
analysis
structures,
diversity,
economic
adaptive
while
discussing
faced
by
this
technology.
aims
provide
scientific
foundation
improvement
conservation
resources.
Язык: Английский
Genomic Characterization of Crossbred-Driven Adaptation in the Endangered Yangba Cattle of China
Animals,
Год журнала:
2025,
Номер
15(7), С. 1065 - 1065
Опубликована: Апрель 6, 2025
This
study
unveils
the
unique
origins,
evolution,
and
genetic
variations
of
Yangba
cattle,
an
endangered
breed
in
China,
through
a
comparative
genomic
analysis
involving
202
individuals
from
21
domestic
international
breeds.
Genetic
component
revealed
that
cattle
comprise
four
ancestral
lineages:
Eurasian
taurine
(18%),
East
Asian
(26%),
Chinese
indicine
(39%),
Indian
(17%).
Their
high
diversity
low
inbreeding
coefficient
set
them
apart
significantly
mainstream
commercial
Gene
introgression
indicated
influx
material
has
enhanced
cattle's
adaptability
to
environmental
stress,
while
endowed
with
advantages
muscle
development
tissue
repair.
A
genome-wide
selection
scan
identified
strong
positive
signals
for
genes
such
as
ABCC2,
which
is
involved
immune
regulation,
NCOA3,
plays
role
growth
cattle.
systematically
elucidates,
first
time,
composite
composition
mechanisms
adaptive
evolution
These
findings
offer
critical
insights
into
conservation
sustainable
utilization
resources
underscore
importance
implementing
effective
breeding
programs.
Язык: Английский