Revisiting the roots of attachment: A review of the biological and psychological effects of maternal skin-to-skin contact and carrying of full-term infants

Infant Behavior and Development, Год журнала: 2020, Номер 60, С. 101441 - 101441

Опубликована: Июнь 27, 2020

Язык: Английский

Autonomic regulation of preterm infants is enhanced by Family Nurture Intervention

Developmental Psychobiology, Год журнала: 2019, Номер 61(6), С. 942 - 952

Опубликована: Март 13, 2019

Abstract Preterm infants have maturational delays in several neurobehavioral systems. This study assesses the impact of Family Nurture Intervention (FNI) neonatal intensive care unit (NICU) on maturation autonomic regulation preterm infants. born at 26–34 weeks postmenstrual age (PMA) were assigned to groups receiving either standard (SC) or SC plus FNI, using a randomized controlled trial design. At two collection time points, approximately 35 and 41 PMA, electrocardiograms (ECG) monitored for 1 hour during sleep. Heart rate respiratory sinus arrhythmia (RSA) quantified from ECG. Across FNI group exhibited greater increases RSA (Cohen's d = 0.35) slope between heart rate, as measure vagal efficiency 0.62). These results document that resulted enhanced consistent with cardiac function. previous findings strongly suggest facilitating early nurturing interactions emotional connection their mothers is practicable effective means optimizing postnatal development Interpretation these function also enriches our understanding potential long‐term beneficial outcomes by drawing upon polyvagal theory, which explains how state provides neurophysiological platform optimal co‐regulation infant caregiver, calming cycle model repeated mother/infant positively condition reinforce approach, prosocial behaviors.

Язык: Английский

Nurturing the preterm infant brain: leveraging neuroplasticity to improve neurobehavioral outcomes

Pediatric Research, Год журнала: 2018, Номер 85(2), С. 166 - 175

Опубликована: Окт. 16, 2018

Язык: Английский

Resilience priming: Translational models for understanding resiliency and adaptation to early life adversity

Developmental Psychobiology, Год журнала: 2018, Номер 61(3), С. 350 - 375

Опубликована: Окт. 11, 2018

Abstract Despite the increasing attention to early life adversity and its long‐term consequences on health, behavior, etiology of neurodevelopmental disorders, our understanding adaptations interventions that promote resiliency rescue against such insults are underexplored. Specifically, investigations perinatal period often focus negative events/outcomes. In contrast, positive experiences (i.e. enrichment/parental care//healthy nutrition) favorably influence development nervous endocrine systems. Moreover, some stressors result in demonstrations later‐life resiliency. This review explores underlying mechanisms neuroplasticity follow these translates them into ideas for pediatric settings. The emerging role gut microbiome mediating stress susceptibility is also discussed. Since many outcomes known, it time identify mediators them. These range from enrichment, quality parental care, dietary those target microbiota.

Язык: Английский

The Welch Emotional Connection Screen: validation of a brief mother–infant relational health screen

Acta Paediatrica, Год журнала: 2018, Номер 108(4), С. 615 - 625

Опубликована: Июнь 30, 2018

Abstract Aim The Welch Emotional Connection Screen ( WECS ), assesses mother–infant in clinical settings. It includes: Attraction, Vocal Communication, Facial Sensitivity/Reciprocity and decision of (yes/no). We tested concurrent construct validity the associations with behavioural physiological measures preterm infants. Methods Videos from 76 mothers–infants (gestational age 36 weeks) during an in‐ NICU caregiving paradigm were coded for maternal behaviour. also obtained at 4 months 10 minutes face‐to‐face play (coded positivity infant social engagement) still‐face approach towards mother; electrocardiogram acquired vivo ). Results scores positively associated sensitivity quality vocal contact weeks (caregiving) (face‐to‐face). correlated engagement interactions months. Infants emotionally not connected dyads (vs. dyads) displayed autonomic dysregulation less approach‐seeking behaviour mother interactive/play sessions paradigm. Conclusion This preliminary evidence supports as a valid screen rating mother–preterm emotional connection healthier biobehavioural stress responding.

Язык: Английский

Adverse Behavioral Changes in Adult Mice Following Neonatal Repeated Exposure to Pain and Sucrose

Frontiers in Psychology, Год журнала: 2019, Номер 9

Опубликована: Янв. 21, 2019

Sucrose is recommended for the treatment of pain during minor procedures in preterm infants neonatal intensive care unit (NICU) and currently used worldwide as standard care. We recently reported that adult mice repetitively exposed to sucrose compared water first week life, irrespective exposure an intervention, had significantly smaller brain volumes large white matter, cortical subcortical structures (e.g., hippocampus, striatum, fimbria). These are important stress regulation memory formation. Here, we report effects repeated on behavior mice. Neonatal C57BL/6J (N = 160, 47% male) were randomly assigned one two treatments (sucrose, water) three interventions (needle-prick, tactile, handling). Pups received 10 daily from postnatal day 1 (P1) P6. A single dose 24% or was given orally 2 min before each intervention. At adulthood (P60-85) underwent behavioral testing assess spatial memory, anxiety, motor function, sensitivity, sugar preference. found handling only, poorer short-term water/handling controls (p < 0.05). When pain, treated with repetitive did not differ performance 0.1). preference test showed intervention pups consumed less solution those There no significant group differences motor, sensitivity. In a mouse model closely mimics NICU care, show time treatment, suggesting does protect when administered pain. absence early induced highlighting importance accurate assessment.

Язык: Английский

Family nurture intervention in the NICU increases autonomic regulation in mothers and children at 4-5 years of age: Follow-up results from a randomized controlled trial

PLoS ONE, Год журнала: 2020, Номер 15(8), С. e0236930 - e0236930

Опубликована: Авг. 4, 2020

Background Maturation of multiple neurobehavioral systems, including autonomic regulation, is altered by preterm birth. The purpose this study was to determine the long-term effects Family Nurture Intervention (FNI) in NICU on regulation infants and their mothers. Method A subset mothers (48% infants, 51% mothers) randomly assigned either standard are (SC), or SC plus FNI a prior RCT (ClincalTrials.gov; NCT01439269) returned for follow-up assessments when children were 4 5 years corrected age (CA). ECGs collected 10 minutes while mothers' laps. Heart rate, deviation heart respiratory sinus arrhythmia (RSA)–an index parasympathetic measure vagal efficiency quantified. Results Both group had significantly greater levels RSA compared (child: mean difference = 0.60, 95% CI 0.17 1.03, p 0.008; mother: 0.64, 0.07 1.21, 0.031). In addition, increased more rapidly between infancy 5-year time point (SC +3.11±0.16 loge msec2, +3.67±0.19 msec2 FNI, p<0.05). These results show that rate increase from childhood rapid subjects. Conclusion Although these preliminary based approximately half subjects originally enrolled RCT, they suggest FNI-NICU led healthier both mother child, measured during brief face-to-face socioemotional interaction. Pavlovian co-conditioning mechanism may underly findings can be exploited therapeutically.

Язык: Английский

Sensory-based interventions in the NICU: systematic review of effects on preterm brain development

Pediatric Research, Год журнала: 2021, Номер 92(1), С. 47 - 60

Опубликована: Сен. 10, 2021

Язык: Английский

Immediate parent-infant skin-to-skin study (IPISTOSS): study protocol of a randomised controlled trial on very preterm infants cared for in skin-to-skin contact immediately after birth and potential physiological, epigenetic, psychological and neurodevelopmental consequences

BMJ Open, Год журнала: 2020, Номер 10(7), С. e038938 - e038938

Опубликована: Июль 1, 2020

In Scandinavia, 6% of infants are born preterm, before 37 gestational weeks. Instead continuing in the in-utero environment, maturation needs to occur a neonatal unit with support vital functions, separated from mother's warmth, nutrition and other benefits. Preterm face health neurodevelopment challenges that may also affect family society at large. There is evidence benefit immediate continued skin-to-skin contact (SSC) for term moderately preterm their parents but there knowledge gap on its effect unstable very when initiated immediately after birth. this ongoing randomised controlled trial Stavanger, Norway Stockholm, Sweden, we studying 150 28+0 32+6 weeks, receive care birth SSC parent or conventionally an incubator. The primary outcome cardiorespiratory stability according system score. Secondary outcomes autonomic stability, thermal control, infection time, breastfeeding growth, epigenetic profile, microbiome infant behaviour, stress resilience, sleep integrity, cortical maturation, neurodevelopment, mother-infant attachment attunement, experience mental health. study has ethical approval Swedish Ethical Review Authority (2017/1135-31/3, 2019-03361) Norwegian Regional Committee (2015/889). conducted good clinical practice Helsinki declaration. results will increase about mechanisms behind effects by dissemination scientific community through articles conferences, parenting classes magazines. Recruiting since April 2018. Expected termination June 2021. NCT03521310 (ClinicalTrials.gov).

Язык: Английский

Early brain activity: Translations between bedside and laboratory

Progress in Neurobiology, Год журнала: 2022, Номер 213, С. 102268 - 102268

Опубликована: Март 29, 2022

Язык: Английский