Association between Muscle Quality Index and Long-Term Depression Risk in Women with Breastfeeding History: A NHANES-Based Cross- Sectional Study
Abstract
Background:
Postpartum
depression
(PPD)
remains
a
significant
challenge
in
women’s
health.
While
breastfeeding
has
been
widely
recognized
as
protective
factor
against
PPD,
women
with
history
are
still
at
risk
for
long-term
depression.
This
study
aims
to
explore
the
relationship
between
muscle
quality
index
(MQI)
and
history.
Methods:
cross-sectional
used
data
from
481
2011-2012
National
Health
Nutrition
Examination
Survey
(NHANES).
MQI
was
computed
ratio
of
handgrip
strength
appendicular
skeletal
mass.
Depression
assessed
using
Patient
Questionnaire-9
(PHQ-9).
Logistic
regression
models
were
applied
assess
depression,
controlling
potential
confounders,
including
sociodemographic
factors,
health
status,
lifestyle
behaviors.
Restricted
cubic
spline
(RCS)
analysis
examine
nonlinear
associations.
Results:
After
adjusting
all
covariates,
lower
value
significantly
associated
increased
[odds
(OR)=
0.25,
95%
confidential
interval
(CI):
0.10-0.65].
Women
highest
quartile
had
reduced
odds
compared
those
lowest
(OR
=
0.12,
CI:
0.03-0.44).
A
observed,
critical
threshold
identified
3.32.
Subgroup
analyses
revealed
consistent
associations
across
factors
such
age,
BMI,
smoking
status.
Conclusion:
may
serve
marker
assessing
association
underscores
importance
integrating
physical
markers
into
mental
assessments
more
effective
early
intervention
care.
Research Square (Research Square), Год журнала: 2025, Номер unknown
Опубликована: Март 18, 2025
Язык: Английский