The Hidden Fortress: A Comprehensive Review of Fungal Biofilms with Emphasis on Cryptococcus neoformans

Journal of Fungi, Год журнала: 2025, Номер 11(3), С. 236 - 236

Опубликована: Март 19, 2025

Biofilms are structurally organized communities of microorganisms that adhere to a variety surfaces. These produce protective matrices consisting polymeric polysaccharides, proteins, nucleic acids, and/or lipids promote shared resistance various environmental threats, including chemical, antibiotic, and immune insults. While algal bacterial biofilms more apparent in the scientific zeitgeist, many fungal pathogens also form biofilms. surprisingly common morphologically distinct from multicellular molds mushrooms normally associated with fungi instead an assemblage single-celled organisms. As collection yeast filamentous cells cloaked extracellular matrix, extreme threat public health, especially conjunction surgical implants. The encapsulated yeast, Cryptococcus neoformans, is opportunistic pathogen causes both pulmonary disseminated infections, particularly immunocompromised individuals. However, there emerging trend cryptococcosis among otherwise healthy C. neoformans forms diverse environments, within human hosts. Notably, biofilm association correlates increased expression multiple virulence factors host defenses antifungal treatments. Thus, it crucial develop novel strategies combat In this review, we discuss development treatment biofilms, particular focus on neoformans.

Язык: Английский

---

A greener side of health care: Revisiting phytomedicine against the human fungal pathogen Malassezia

Fitoterapia, Год журнала: 2024, Номер 179, С. 106243 - 106243

Опубликована: Окт. 9, 2024

Язык: Английский

---

APMIS focus issue 2024—The microenvironment in human disease

Apmis, Год журнала: 2024, Номер 132(12), С. 903 - 905

Опубликована: Ноя. 8, 2024

Язык: Английский

---