Journal of Gastrointestinal and Liver Diseases, Год журнала: 2024, Номер 33(4), С. 488 - 495
Опубликована: Дек. 28, 2024
Despite reports of brain fog in patients with inflammatory bowel disease (IBD), empirical research into this phenomenon has been lacking. This study aimed to validate a scale and explore the relationships between IBD symptom activity, fog, fatigue, psychological distress, quality life (QoL).
Язык: Английский
JGH Open, Год журнала: 2024, Номер 8(7)
Опубликована: Июль 1, 2024
Abstract The traditional gut‐centric view of coeliac disease is evolving as immune and genetic insights underscore the central importance a systemic, T cell response to gluten in pathogenesis. As field increasingly recognize limitations small intestinal histology diagnostic standard, data supporting accuracy an (serologic) diagnosis ‐ well demonstrated children are growing for adults. Novel biomarkers such interleukin‐2 that identify gluten‐specific demonstrate high sensitivity specificity offer potential approach avoids need challenge. Asymptomatic manifestations outside gut pose considerable challenges using case‐finding strategy enthusiasm population screening growing. gluten‐free diet remains highly restrictive treatment there paucity controlled inform safe intake threshold. Ongoing symptoms enteropathy common require systematic evaluation. Slowly‐responsive prevalent older patient diagnosed with disease, super‐sensitivity emerging concept may explain many cases nonresponsive disease. While great interest developing novel therapies no drug has yet been registered. Efficacy studies generally assessing drugs patients treated who undergo challenge or disease; however, substantial questions remain around specific endpoints relevant patients, clinicians regulatory agencies optimal trial design. tools providing informative readouts clinical trials now shaping their
Язык: Английский
Процитировано
4
Trends in Neurosciences, Год журнала: 2025, Номер unknown
Опубликована: Фев. 1, 2025
'Brain fog' is commonly reported in more than a dozen chronic diseases, but what it? We review research across conditions which has characterised brain fog and evaluate its definitions objective correlates. Brain been used to refer variable set of overlapping symptoms implicating cognition, fatigue, affect. It defined as distinct symptom, syndrome, or nonspecific term. consider the evidence that transdiagnostic entity with common phenomenology profile cognitive deficits. discuss where these commonalities arise argue linguistic ambiguity, shared impairments, noncognitive factors are likely neurobiology. suggest how future might apply existing tools disambiguate phenomena conflates.
Язык: Английский
Процитировано
0
Psychology Research and Behavior Management, Год журнала: 2025, Номер Volume 18, С. 589 - 606
Опубликована: Март 1, 2025
Abstract: The term "brain fog" has long been used both colloquially and in research literature reference to various neurocognitive phenomenon that detract from cognitive efficiency. We define as the subjective experience of difficulties, keeping with most common colloquial use term. While a recent increase this largely context post-coronavirus-19 condition known COVID, also discussed relation several other conditions including mental health such post-traumatic stress disorder (PTSD). PTSD is associated complaints relative deficits on testing, but phenomenology mechanisms contributing population are poorly understood. psychopathology across cognitive, affective physiological symptom domains have tied fog". Furthermore, dissociative symptoms contribute Comorbid physical may risk experiencing among individuals PTSD. Considerations for assessment part psychodiagnostic discussed. standard psychological intervention reduction deficits, interventions be valuable when persists following remission or interferes treatment. Limitations current include lack consistent definition operationalization literature, well limited tools measurement. Future should address these limitations, further evaluate remediation an Keywords: cognition, complaints, fatigue, trauma
Язык: Английский
Процитировано
0
Alimentary Pharmacology & Therapeutics, Год журнала: 2024, Номер 59(12), С. 1628 - 1629
Опубликована: Апрель 21, 2024
LINKED CONTENT This article is linked to Knowles et al paper. To view this article, visit https://doi.org/10.1111/apt.17942
Язык: Английский
Процитировано
0
International Journal of Neuroscience, Год журнала: 2024, Номер unknown, С. 1 - 11
Опубликована: Авг. 29, 2024
Post coronavirus disease 2019 (COVID-19) pandemic, the widespread emergence and persistence of brain fog has led to a decline in people's productivity quality life. However, clinical characteristics COVID-19-associated are unclear, standardized assessments lacking. This study aims develop scale for assessment support practice research.
Язык: Английский
Процитировано
0
World Journal of Gastrointestinal Endoscopy, Год журнала: 2024, Номер 16(12), С. 632 - 639
Опубликована: Дек. 11, 2024
Celiac disease is an autoimmune condition that affects approximately 1% of the worldwide community. Originally thought to be confined mostly small intestine, resulting in villous atrophy and nutrient malabsorption, it has more recently been implicated systemic manifestations as well, particularly when undiagnosed or left untreated. Herein, physical psychological symptoms celiac are described explored. An emphasis placed on efforts query prospective confirmed patients
Язык: Английский
Процитировано
0
Alimentary Pharmacology & Therapeutics, Год журнала: 2024, Номер 61(1), С. 4 - 5
Опубликована: Дек. 12, 2024
Язык: Английский
Процитировано
0
Journal of Gastrointestinal and Liver Diseases, Год журнала: 2024, Номер 33(4), С. 488 - 495
Опубликована: Дек. 28, 2024
Despite reports of brain fog in patients with inflammatory bowel disease (IBD), empirical research into this phenomenon has been lacking. This study aimed to validate a scale and explore the relationships between IBD symptom activity, fog, fatigue, psychological distress, quality life (QoL).
Язык: Английский
Процитировано
0