Alcohol Clinical and Experimental Research, Год журнала: 2024, Номер unknown
Опубликована: Дек. 30, 2024
Alcohol-associated hepatitis (AH) is a subtype of alcohol-associated liver disease (ALD) resulting in severe acute inflammation. This study aims to examine longitudinal trends mortality from AH the United States (US) 1999 2020, stratifying data by sex, age, and racial/ethnic groups.
Язык: Английский
Hepatology Communications, Год журнала: 2025, Номер 9(1)
Опубликована: Янв. 1, 2025
Background: The incidence of cancer and the prevalence metabolic disease dysfunction–associated steatotic liver is increasing in young adults. However, updated global data on steatohepatitis (MASH)-associated primary (PLC) adults remains scarce. Methods: This study analyzed from Global Burden Disease between 2000 2021 to assess age-standardized incidence, mortality, disability-adjusted life years rates MASH-associated PLC (15–49 y). Results: In 2021, there were 4300 cases, 3550 deaths, 179,340 Among various etiologies adults, only had increased (annual percent change: +0.26, 95% CI: 0.16%–0.35%), with Eastern Mediterranean region having largest observed increase 1.46%, 1.40%–1.51%). made up 6% (+1% 2000) incident (+2% all this age group. Over half countries exhibited an rate 2021. Conclusions: significantly increasing, signaling likely future increases among older as cohort ages. trend necessitates urgent strategies worldwide mitigate epidemics
Язык: Английский
Процитировано
2
Scientific Reports, Год журнала: 2024, Номер 14(1)
Опубликована: Авг. 22, 2024
Primary liver cancer is the third leading cause of cancer-related mortality. The increasing prevalence metabolic syndrome and alcohol consumption, along with existing burden viral hepatitis, could significantly heighten impact primary cancer. However, specific effects these factors in Asia–Pacific region, which comprises more than half global population, remain largely unexplored. This study aims to analyze epidemiology region. We evaluated regional national data from Global Burden Disease spanning 2010 2019 assess age-standardized incidence, mortality, disability-adjusted life years associated During period, there were an estimated 364,700 new cases 324,100 deaths, accounting for 68 67% totals, respectively. Upward trends observed incidence rates due dysfunction-associated fatty disease (MASLD) alcohol-associated (ALD) as well increase Hepatitis B virus infection Western Pacific Notably, approximately 17% occurred individuals aged 15–49 years. Despite overall decline region over past decade, increases noted several etiologies, including MASLD ALD. hepatitis remains cause, responsible 60% total burden. These findings underscore urgent need comprehensive strategies address rising
Язык: Английский
Процитировано
6
Alimentary Pharmacology & Therapeutics, Год журнала: 2024, Номер 60(4), С. 521 - 522
Опубликована: Июль 5, 2024
LINKED CONTENT This article is linked to Danpanichkul et al papers. To view these articles, visit https://doi.org/10.1111/apt.18101 and https://doi.org/10.1111/apt.18140
Язык: Английский
Процитировано
3
Frontiers in Public Health, Год журнала: 2025, Номер 12
Опубликована: Янв. 8, 2025
Chronic hepatitis B and cirrhosis pose significant global health threats. Few studies have explored the disease burden mortality trend of caused by virus infection among adolescents young adults (AYAs, aged 15-39 years). This study aimed to assess trends. Publicly available data were obtained from 2021 GBD database. The rates incidence, mortality, disability-adjusted life years calculated at global, regional, national levels. Temporal trends assessed using joinpoint regression analysis, while Bayesian age-period-cohort model was used predict future From 1990 2021, incidence rate B-related decreased 111.33 (95% uncertainty interval: 89.18 134.98) 67.75 (54.06 82.71) per 100,000 with an average annual percentage change -1.58 confidence -1.66 -1.51, p < 0.001). However, between numbers in 30-34 35-39 age groups increased 23.75 21.24%, respectively. number deaths low low-middle Socio-demographic Index (SDI) areas 79.51 20.62%, Moreover, it is predicted that incidences will continue rise SDI. At regional level, Central Sub-Saharan Africa had highest rates. In Somalia Democratic Republic Congo rates, whereas Kiribati Cambodia overall AYAs has over past three decades. Nevertheless, there a slight increase individuals 30-39 years. substantial SDI underscore need for sustained targeted public interventions.
Язык: Английский
Процитировано
0
Addiction, Год журнала: 2025, Номер unknown
Опубликована: Март 5, 2025
Adolescent alcohol consumption decreased in high-income countries during the 2000s and 2010s. While evidence for declining is clear, there has been less research tracking trends alcohol-related harms. This article reviewed adolescent harms where a decline had occurred investigated sex-based differences trends. The databases Medline, CINAHL, Scopus PubMed were systematically searched, with grey literature searches also conducted. Studies included if they reported on harm rates between 2005 2019 adolescents (10-19 years) from reduction drinking occurred. Health-system based measures of used (e.g. hospital admissions or mortality data). Search terms alcohol, adolescents, harms, synonyms. Risk bias was assessed, primary screening conducted by one author checks another, data extraction completed three authors accuracy results are presented via narrative synthesis. Systematic resulted 1311 results. A total 18 systematic search 23 sources included. For many countries, have since 2005, following consumption. strongest Anglosphere eight thirteen records (62%) indicated declines, followed North America, declines present four eleven (36%). Trends mainland Europe contradictory, only (31%) indicating decreases Increases some female student populations jurisdictions. Alcohol-related young people generally declined youth fallen, although smaller than drinking. Declines United Kingdom, Australia, New Zealand Ireland, America.
Язык: Английский
Процитировано
0
Scientific Reports, Год журнала: 2025, Номер 15(1)
Опубликована: Апрель 3, 2025
Язык: Английский
Процитировано
0
Alimentary Pharmacology & Therapeutics, Год журнала: 2024, Номер 60(4), С. 519 - 520
Опубликована: Июль 5, 2024
LINKED CONTENT This article is linked to Danpanichkul et al papers. To view these articles, visit https://doi.org/10.1111/apt.18101 and https://doi.org/10.1111/apt.18157
Язык: Английский
Процитировано
2
Alimentary Pharmacology & Therapeutics, Год журнала: 2024, Номер 60(8), С. 1156 - 1157
Опубликована: Сен. 5, 2024
LINKED CONTENT This article is linked to Danpanichkul et al papers. To view these articles, visit https://doi.org/10.1111/apt.18101 and https://doi.org/10.1111/apt.18239
Язык: Английский
Процитировано
2
Alimentary Pharmacology & Therapeutics, Год журнала: 2024, Номер 60(8), С. 1154 - 1155
Опубликована: Сен. 23, 2024
LINKED CONTENT This article is linked to Danpanichkul et al papers. To view these articles, visit https://doi.org/10.1111/apt.18101 and https://doi.org/10.1111/apt.18250
Язык: Английский
Процитировано
2
Drug and Alcohol Dependence, Год журнала: 2024, Номер 266, С. 112495 - 112495
Опубликована: Ноя. 14, 2024
Язык: Английский
Процитировано
2