Role of mucous cells in the defence system of the cnidarian Actinia equina (Linnaeus, 1758): The keystone of evolution DOI Open Access
Alessio Alesci, Sebastián Marino,

Anthea Miller

и другие.

Acta Zoologica, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 8, 2024

Abstract Cnidarians are the first phylum of metazoans to exhibit a functional mucus layer. In evolution, mucous cells perform classical secretory function and act as sentinels for external insults, particularly in mammals. However, this topic has not been much analysed lower metazoans. This study aims investigate role Actinia equina (Anthozoa, Hexacorallia) (Linnaeus, 1758) by using confocal microscopy bioinformatics. The results show colocalization Toll‐like receptor 2 (TLR2) Mucin2 (MUC2) on these cells, suggesting crosstalk between defence response secretion cnidarians. Furthermore, presence TLR2 surface suggests their involvement host responses, occurs vertebrates. Moreover, through silico analysis, we confirmed orthologous genes tested antibodies, providing additional evidence support our from an evolutionary perspective. These data suggest that play defensive throughout helping us understand how have developed adapted across phylogenesis. information also provides new insights into strategies invertebrates clarifies history.

Язык: Английский

Influence of serotonin (5-HT) on locomotor behavior and digestive physiology in the sea cucumber Apostichopus japonicus DOI
Yucheng Ren,

Xiuwen Xu,

Xudong Liang

и другие.

Aquaculture, Год журнала: 2025, Номер unknown, С. 742432 - 742432

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Internal Defense System of Mytilus galloprovincialis (Lamarck, 1819): Ecological Role of Hemocytes as Biomarkers for Thiacloprid and Benzo[a]Pyrene Pollution DOI Creative Commons
Alessio Alesci,

Davide Di Paola,

Angelo Fumia

и другие.

Toxics, Год журнала: 2023, Номер 11(9), С. 731 - 731

Опубликована: Авг. 25, 2023

The introduction of pollutants, such as thiacloprid and benzo[a]pyrene (B[a]P), into the waters urbanized coastal estuarine areas through fossil fuel spills, domestic industrial waste discharges, atmospheric inputs, continental runoff poses a major threat to fauna flora aquatic environment can have significant impact on internal defense system invertebrates mussels. Using monoclonal polyclonal anti-Toll-like receptor 2 (TLR2) anti-inducible nitric oxide synthetase (iNOS) antibodies for first time, this work aims examine hemocytes in mantle gills M. galloprovincialis biomarkers B[a]P pollution analyze their potential synergistic effect. To pursue objective, samples were exposed both individually simultaneously. Subsequently, oxidative stress evaluated by enzymatic analysis, while tissue changes number different contaminated groups assessed via histomorphological immunohistochemical analyses. Our findings revealed that comparison single exposure, two pollutants together significantly elevated stress. Moreover, our data may potentially enhance knowledge how TLR2 iNOS part bivalves. This would help creating new technologies strategies, biosensors, are more suitable managing water pollution, garnering details condition marine ecosystem.

Язык: Английский

Процитировано

4
Role of mucous cells in the defence system of the cnidarian Actinia equina (Linnaeus, 1758): The keystone of evolution DOI Open Access
Alessio Alesci, Sebastián Marino,

Anthea Miller

и другие.

Acta Zoologica, Год журнала: 2024, Номер unknown

Опубликована: Ноя. 8, 2024

Abstract Cnidarians are the first phylum of metazoans to exhibit a functional mucus layer. In evolution, mucous cells perform classical secretory function and act as sentinels for external insults, particularly in mammals. However, this topic has not been much analysed lower metazoans. This study aims investigate role Actinia equina (Anthozoa, Hexacorallia) (Linnaeus, 1758) by using confocal microscopy bioinformatics. The results show colocalization Toll‐like receptor 2 (TLR2) Mucin2 (MUC2) on these cells, suggesting crosstalk between defence response secretion cnidarians. Furthermore, presence TLR2 surface suggests their involvement host responses, occurs vertebrates. Moreover, through silico analysis, we confirmed orthologous genes tested antibodies, providing additional evidence support our from an evolutionary perspective. These data suggest that play defensive throughout helping us understand how have developed adapted across phylogenesis. information also provides new insights into strategies invertebrates clarifies history.

Язык: Английский

Процитировано

0