International Journal of Clinical Pharmacy, Год журнала: 2016, Номер 38(2), С. 454 - 461
Опубликована: Март 7, 2016
Язык: Английский
Journal of General Internal Medicine, Год журнала: 2025, Номер unknown
Опубликована: Янв. 29, 2025
Язык: Английский
Процитировано
1
JAMA Network Open, Год журнала: 2025, Номер 8(2), С. e2457498 - e2457498
Опубликована: Фев. 10, 2025
Importance Better understanding of patients’ attitudes toward deprescribing specific medications will inform future interventions. Objective To investigate older adults’ by investigating which they would like to have deprescribed, the reasons why, and patient factors associated with interest in deprescribing. Design, Setting, Participants This survey study was conducted from May 2022 December 2023 primary care settings 14 countries. Patients aged 65 years or taking 5 more were consecutively recruited their general practitioner (GP) completed questionnaire. Exposures Patient characteristics, including gender, number medications, GP education level, financial status, confidence completing medical forms, self-rated health, satisfaction trust GP, country. Main Outcomes Measures The outcomes as measured responses question, “Thinking about your current medication list, are there any that you stop reduce dose of?” Multilevel multivariable logistic regression analysis used, adjusted for clustering effect at country association between characteristics Results Of 1340 patients (mean [SD], 96 [47] per country), 736 (55%) women, 580 (44%) had secondary school highest level education, 1089 (82%) satisfied 589 expressed deprescribe 1 medications. varying levels, 79% (86 109 patients) Poland 23% (21 Bulgaria. 3 most reported deprescribed diuretics (111 1002 [11%]), lipid-modifying agents (109 acting on renin-angiotensin system (83 [8%]). odds naming least lower higher (odds ratio, 0.31; 95% CI, 0.21-0.47) 0.960; 0.930-0.998). Conclusions Relevance In this older, varied across countries, demonstrating interventions could be impactful when adapted contexts. These findings highlight importance patient-practitioner communication ensuring appropriate use.
Язык: Английский
Процитировано
1
The Medical Journal of Australia, Год журнала: 2014, Номер 201(7), С. 386 - 389
Опубликована: Окт. 1, 2014
Deprescribing is the process of trial withdrawal inappropriate medications. Currently, strongest evidence for benefit deprescribing from cohort and observational studies specific medication classes that have shown better patient outcomes, mainly through resolution adverse drug reactions. Additional potential benefits include reduced financial costs improved adherence with other The harms ceasing use reactions, pharmacokinetic pharmacodynamic changes return medical condition. These can be minimised proper planning (ie, tapering), monitoring after withdrawal, reinitiation if condition returns. More needed regarding negative, non-reversible effects certain medication, such as acetylcholinesterase inhibitors. Cessation has not been studied many classes, large-scale randomised controlled trials systematic are required before true known.
Язык: Английский
Процитировано
90
International Journal of Clinical Pharmacy, Год журнала: 2015, Номер 38(1), С. 46 - 53
Опубликована: Ноя. 23, 2015
Background Knowledge of drug-related problems (DRPs) identified in the medication home-dwelling elderly patients with polypharmacy has been based predominantly on reviews conducted research settings rather than daily practice. Objective To evaluate prevalence DRPs by means a clinical review (CMR) and implementation rate proposed interventions large group older practice community pharmacies. Setting 318 Dutch Method A cross-sectional study CMR-data 3807 (≥65 years) (≥5 drugs) completed between January August 2012. Data were extracted from pharmacists' databases entailed: year birth, gender, dispensing data, number nature DRPs, consultations performed, implemented interventions. Main outcome measure Prevalence drug classes involved overtreatment undertreatment, Results median two (interquartile range 1–4; mean 3.0) was per patient. The DRP-categories (25.5 %) undertreatment (15.9 found most frequently. 46.2 % to solve as proposed, 22.4 cases, intervention differed proposal. In 31.3 cases no implemented. Conclusion By conducting CMR pharmacists polypharmacy. Overtreatment accounted for 41.4 identified. dealing variety which majority (69.9 either or led alternative set explicit criteria should be applied during prevent DRPs.
Язык: Английский
Процитировано
87
International Journal of Clinical Pharmacy, Год журнала: 2016, Номер 38(2), С. 454 - 461
Опубликована: Март 7, 2016
Язык: Английский
Процитировано
83