Seasonal Trends in HLA‐B27‐Associated Uveitis: A Commentary on Recent Findings

Clinical and Experimental Ophthalmology, Год журнала: 2025, Номер unknown

Опубликована: Март 27, 2025

I read with great interest the recently published article by Samalia et al. [1] titled 'Seasonal Variation in HLA-B27-Associated Uveitis' Clinical & Experimental Ophthalmology. This study provides valuable insights into seasonal patterns of HLA-B27-associated uveitis, particularly New Zealand population. Their findings suggest an increased incidence uveitis during winter months, inverse relationship observed between and both temperature sunlight exposure. adds to growing body literature examining influence environmental factors on ocular inflammation. Several recent studies have explored seasonality its association climatic factors. Surapaneni [2] investigated fluctuations flare-ups Connecticut, reporting a subset HLA-B27-positive patients experiencing temperature-related variations. Similarly, epidemiological Northern Italy Menean [3] highlighted regional influences presentation. Liu [4] further demonstrated that HLA-B27 positivity is strong predictor acute anterior (AAU) Chinese Spondyloarthritis Registry, playing significant role. Additionally, Kawali [5] HLA-B27-related cooler months Indian cohort, reinforcing global nature this phenomenon. While al.'s substantially advances our understanding seasonality, additional research warranted elucidate underlying mechanisms. Longitudinal assessments such as air pollution humidity could provide deeper external triggers disease onset exacerbation. Furthermore, closely linked systemic inflammatory conditions like ankylosing spondylitis, concurrent evaluations rheumatologic activity may help clarify shared pathways. In conclusion, underscore need for heightened clinical vigilance managing high-incidence periods. Multi-regional, longitudinal are essential investigate immunological interactions influencing progression guide preventive strategies at-risk individuals. We utilised Microsoft Copilot 365 grammar language refinement. All intellectual content, critical discussions, interpretations were solely conceived developed authors. The final manuscript was thoroughly reviewed approved authors prior submission, ensuring full accountability content. declare no conflicts interest. Data sharing not applicable datasets generated or analysed current study.

Язык: Английский

Seasonal Trends in HLA‐B27‐Associated Uveitis: A Commentary on Recent Findings—Response

Clinical and Experimental Ophthalmology, Год журнала: 2025, Номер unknown

Опубликована: Апрель 3, 2025

Язык: Английский