ANXA2 in cancer: aberrant regulation of tumour cell apoptosis and its immune interactions DOI Creative Commons
Le Huang, Kai Xu,

Qingping Yang

и другие.

Cell Death Discovery, Год журнала: 2025, Номер 11(1)

Опубликована: Апрель 15, 2025

Abstract Annexin A2 (ANXA2) is a multifunctional protein that binds to calcium and phospholipids plays critical role in various pathological conditions, including cancer inflammation. Recently, there has been increasing recognition of the significant ANXA2 inhibiting apoptosis promoting immune evasion tumour cells. Therefore, deep understanding regulatory mechanisms cell its relationship with can provide new targets for therapy. This review summarizes regulating cells, connection between regulation immunity, potential therapy resistance.

Язык: Английский

ANXA2 in cancer: aberrant regulation of tumour cell apoptosis and its immune interactions DOI Creative Commons
Le Huang, Kai Xu,

Qingping Yang

и другие.

Cell Death Discovery, Год журнала: 2025, Номер 11(1)

Опубликована: Апрель 15, 2025

Abstract Annexin A2 (ANXA2) is a multifunctional protein that binds to calcium and phospholipids plays critical role in various pathological conditions, including cancer inflammation. Recently, there has been increasing recognition of the significant ANXA2 inhibiting apoptosis promoting immune evasion tumour cells. Therefore, deep understanding regulatory mechanisms cell its relationship with can provide new targets for therapy. This review summarizes regulating cells, connection between regulation immunity, potential therapy resistance.

Язык: Английский

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