Frontiers in Pharmacology, Год журнала: 2025, Номер 16

Опубликована: Фев. 5, 2025

The SOX9 gene locus is not only extensive but also intricate, and it could promote fibrosis in different organs or tissues, including cardiac fibrosis, liver kidney pulmonary as well other organ fibrosis. Many disorders are associated with the process of fibrosis; moreover, a common symptom chronic inflammatory diseases, characterized by accumulation excessive components extracellular matrix through signaling pathways. advanced stage fibrotic leads to dysfunction and, ultimately, death. In this review, we first give an overview original structure functions SOX9. Second, will discuss role various tissues. Third, describe reveal possibility antifibrotic treatment target. Finally, focus on application novel technologies for subsequent investigation

Язык: Английский