Constraints to gene flow increase the risk of genome erosion in the Ngorongoro Crater lion population DOI Creative Commons
Nicolás Dussex, Ingela Jansson, Tom van der Valk

и другие.

Communications Biology, Год журнала: 2025, Номер 8(1)

Опубликована: Апрель 21, 2025

Abstract Small, isolated populations are at greater risk of genome erosion than larger populations. Successful conservation efforts may lead to demographic recovery and mitigate the negative genetic effects bottlenecks. However, constrained gene flow can hamper genomic recovery. Here, we use population analyses forward simulations assess impacts near extinction in Ngorongoro Crater lion ( Panthera leo ) sub-population. We show that 200 years quasi-isolation recent epizootic 1962 resulted a two-fold increase inbreeding an excess frequency highly deleterious mutations relative other Greater Serengeti. There was little evidence for purging load. Furthermore, indicate higher from outside is needed prevent future population, with minimum one five effective male migrants per decade required reduce long-term depression reduction diversity. Our results suggest spite rapid post-epizootic since 1970s, continued isolation driven by habitat fragmentation potentially territoriality, exacerbate erosion.

Язык: Английский

Constraints to gene flow increase the risk of genome erosion in the Ngorongoro Crater lion population DOI Creative Commons
Nicolás Dussex, Ingela Jansson, Tom van der Valk

и другие.

Communications Biology, Год журнала: 2025, Номер 8(1)

Опубликована: Апрель 21, 2025

Abstract Small, isolated populations are at greater risk of genome erosion than larger populations. Successful conservation efforts may lead to demographic recovery and mitigate the negative genetic effects bottlenecks. However, constrained gene flow can hamper genomic recovery. Here, we use population analyses forward simulations assess impacts near extinction in Ngorongoro Crater lion ( Panthera leo ) sub-population. We show that 200 years quasi-isolation recent epizootic 1962 resulted a two-fold increase inbreeding an excess frequency highly deleterious mutations relative other Greater Serengeti. There was little evidence for purging load. Furthermore, indicate higher from outside is needed prevent future population, with minimum one five effective male migrants per decade required reduce long-term depression reduction diversity. Our results suggest spite rapid post-epizootic since 1970s, continued isolation driven by habitat fragmentation potentially territoriality, exacerbate erosion.

Язык: Английский

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