Experimentally Elevated Levels of Testosterone Advance Daily Onset of Activity in Short‐Day Housed Male House Sparrows (Passer domesticus) DOI
Holland Galante, Samuel J. Lane, Emily K. Elderbrock

и другие.

Journal of Experimental Zoology Part A Ecological and Integrative Physiology, Год журнала: 2024, Номер 341(10), С. 1073 - 1083

Опубликована: Окт. 7, 2024

ABSTRACT Seasonal changes in sleep/wake cycles and behaviors related to reproduction often co‐occur with seasonal fluctuations sex hormones. Experimental studies have established that circulating testosterone mediate circadian rhythms. However, most are performed under constant lighting conditions fail investigate the effects of on phenotypic output rhythms, is, chronotype (daily activity patterns light:dark cycles). Here, we experimentally elevated implants during short nonbreeding daylengths male house sparrows ( Passer domesticus ) test if observed directly response photoperiod or testosterone. We fitted individuals accelerometers track across treatment periods. Birds experienced three treatments periods: day photoperiods before manipulation (SD), followed by while still days (SD + T). Implants were then removed. After a decrease cloacal protuberance size, an indicator low levels, birds photostimulated long (LD). Blood samples collected at night, when peaks, compare levels daily onset/offset for experimental Our results indicate significantly advanced onset total relative daylength. This suggests testosterone, independent photoperiod, is responsible shifts chronotypes These findings suggest steroid hormone actions regulate timing behaviors, likely coordinating expression reproductive appropriate times day.

Язык: Английский

Understanding the Intricacies of Cellular Mechanisms in Remyelination: The Role of Circadian Rhythm DOI Creative Commons
Yufen Tang, Lu Zhang, Peng Huang

и другие.

Neurochemistry International, Год журнала: 2025, Номер 183, С. 105929 - 105929

Опубликована: Янв. 5, 2025

Язык: Английский

Процитировано

0
Endocrine regulation of circadian rhythms DOI Creative Commons
Kimberly Begemann, Oliver Rawashdeh, Iwona Olejniczak

и другие.

Deleted Journal, Год журнала: 2025, Номер 2(1)

Опубликована: Март 8, 2025

Abstract Circadian clocks are internal timekeepers enabling organisms to adapt recurrent events in their environment – such as the succession of day and night—by controlling essential behaviors food intake or sleep-wake cycle. A ubiquitous cellular clock network regulates numerous physiological processes including endocrine system. Levels several hormones melatonin, cortisol, sex hormones, thyroid stimulating hormone well a number metabolic factors vary across day, some them, turn, can feedback on circadian rhythms. In this review, we dissect principal ways by which regulate rhythms target tissues phasic drivers rhythms, zeitgebers resetting tissue phase, tuners, affecting downstream more tonic fashion without core clock. These data emphasize intricate interaction system offer inroads into tissue-specific manipulation organization.

Язык: Английский

Процитировано

0
IL-6 decodes sex and diet-dependent circadian and metabolic rhythms DOI Creative Commons

Antía González-Vila,

Ali Mohammad Ibrahim-Alasoufi,

María Luengo-Mateos

и другие.

Molecular Metabolism, Год журнала: 2025, Номер 97, С. 102171 - 102171

Опубликована: Май 22, 2025

Язык: Английский

Процитировано

0
Astrocytes in the mouse suprachiasmatic nuclei respond directly to glucocorticoids feedback DOI Open Access
Kristian Händler, Varun K. A. Sreenivasan, Violetta Pilorz

и другие.

bioRxiv (Cold Spring Harbor Laboratory), Год журнала: 2024, Номер unknown

Опубликована: Март 6, 2024

Abstract The circadian timing system anticipates daily recurring changes in the environment to synchronize physiology. In mammals, master pacemaker is hypothalamic suprachiasmatic nuclei (SCN), which synchronizes “wake” functions by inducing release of Glucocorticoids (GCs) from adrenal gland. GCs peak right before active phase and set time peripheral clocks, however, it still unclear whether SCN respond feedback. While influence directly during perinatal period, adult circuit considered be resistant them, suggesting a reduction GCs-sensitivity along development. To understand this mechanism, we followed expression GC receptor (GR) mouse development with single-cell resolution show that GR up-regulated astrocytes as matures. We provide vivo vitro evidence stays responsive circulating through activation astrocytes. Astrocytes’ communication necessary induce GC-dependent shift on clock. Our data provides insight into highlight new role time-keepers adult. This finding might shed light how adapts jetlag or work.

Язык: Английский

Процитировано

0
Experimentally Elevated Levels of Testosterone Advance Daily Onset of Activity in Short‐Day Housed Male House Sparrows (Passer domesticus) DOI
Holland Galante, Samuel J. Lane, Emily K. Elderbrock

и другие.

Journal of Experimental Zoology Part A Ecological and Integrative Physiology, Год журнала: 2024, Номер 341(10), С. 1073 - 1083

Опубликована: Окт. 7, 2024

ABSTRACT Seasonal changes in sleep/wake cycles and behaviors related to reproduction often co‐occur with seasonal fluctuations sex hormones. Experimental studies have established that circulating testosterone mediate circadian rhythms. However, most are performed under constant lighting conditions fail investigate the effects of on phenotypic output rhythms, is, chronotype (daily activity patterns light:dark cycles). Here, we experimentally elevated implants during short nonbreeding daylengths male house sparrows ( Passer domesticus ) test if observed directly response photoperiod or testosterone. We fitted individuals accelerometers track across treatment periods. Birds experienced three treatments periods: day photoperiods before manipulation (SD), followed by while still days (SD + T). Implants were then removed. After a decrease cloacal protuberance size, an indicator low levels, birds photostimulated long (LD). Blood samples collected at night, when peaks, compare levels daily onset/offset for experimental Our results indicate significantly advanced onset total relative daylength. This suggests testosterone, independent photoperiod, is responsible shifts chronotypes These findings suggest steroid hormone actions regulate timing behaviors, likely coordinating expression reproductive appropriate times day.

Язык: Английский

Процитировано

0