Oral frailty five‐item checklist to predict adverse health outcomes in community‐dwelling older adults: A Kashiwa cohort study

Geriatrics and gerontology international/Geriatrics & gerontology international, Год журнала: 2023, Номер 23(9), С. 651 - 659

Опубликована: Июль 17, 2023

To enable easy assessment of oral frailty; that is, an overlapping slight decline in multifaceted function, any setting, we developed the frailty five-item checklist (OF-5), and examined its predictive validity for increased risks physical frailty, disability mortality among community-dwelling older adults.

Язык: Английский

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Impact of Multidomain Frailty on the Mode of Death in Older Patients With Heart Failure: A Cohort Study

Circulation Cardiovascular Quality and Outcomes, Год журнала: 2024, Номер 17(5)

Опубликована: Май 1, 2024

Although frailty is strongly associated with mortality in patients heart failure (HF), the risk of which specific cause death being complicated unclear. We aimed to clarify association between multidomain and causes elderly hospitalized HF. analyzed data from FRAGILE-HF cohort, where aged 65 years older, HF, were prospectively registered 2016 2018 15 Japanese hospitals before discharge followed up for 2 years. All assessed physical, social, cognitive dysfunction, categorized into 3 groups based on their number domains (FDs, 0-1, 2, 3). Kaplan-Meier survival analysis was used evaluate FDs all-cause mortality, whereas Fine-Gray competing regression assessing impact cause-specific mortality. 1181 HF (81 old median, 57.4% male), 530 (44.9%), 437 (37.0%), 214 (18.1%) whom FD 0 1, groups, respectively. During 2-year follow-up, 240 deaths observed (99 deaths, 34 cardiovascular 107 noncardiovascular deaths), an increase significantly (Log-rank: P<0.001). The adjusted age sex showed that (subdistribution hazard ratio, 1.77 [95% CI, 1.11-2.81]) (2.78, 1.69-4.59]) higher incidence but not other deaths. older it mostly attributable death, including death. URL: https://www.clinicaltrials.gov; Unique identifier: UMIN000023929.

Язык: Английский

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Predictive validity of the Questionnaire for Medical Checkup of Old‐Old for functional disability: Using the National Health Insurance Database System

Geriatrics and gerontology international/Geriatrics & gerontology international, Год журнала: 2023, Номер 23(2), С. 124 - 130

Опубликована: Янв. 13, 2023

To enhance health services that can address multifaceted issues, the Questionnaire for Medical Checkup of Old-Old (QMCOO) was strategically developed to ascertain frailty status. Using National Health Insurance database system, we aimed clarify whether QMCOO predict new certifications long-term care disabilities.Of 20 151 adults aged ≥75 years who underwent checkups in Kashiwa City, Japan, fiscal year 2020 (examination rate 36.8%), 18 130 persons were included (mean age 80.1 ± 4.1 years, 55.1% women). The outcome certification until January 2022. From medical receipt data, QMCOO, age, sex, living arrangement, body mass index, comorbidity, and musculoskeletal connective tissue diseases evaluated.During follow-up period, 727 (4.0%) participants had an incident disability (median follow up 457 days [quartile range 408-519 days]). QMCOO's predictive accuracy needs optimal when total score 3/4 used as threshold. Older with scores ≥4 a higher adjusted hazard ratio (adjusted 2.5, 95% confidence interval 2.1-2.9). Furthermore, greatly enhanced comorbidity (6.6, 4.8-8.9).The which reflects frailty, might be disability, its could improved by considering comorbidities. comprehensive contribute extending healthy life expectancy through efficiently assessing preventing care, even among old-old latter stage tended suffer from multimorbidity. Geriatr Gerontol Int 2023; 23: 124-130.

Язык: Английский

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Factors Associated with Sarcopenia among Elderly Individuals Residing in Community and Nursing Home Settings: A Systematic Review with a Meta-Analysis

Nutrients, Год журнала: 2023, Номер 15(20), С. 4335 - 4335

Опубликована: Окт. 11, 2023

To investigate the factors associated with sarcopenia in elderly individuals residing nursing homes and community settings, we conducted a systematic search of databases, including MEDLINE, EMBASE, PubMed, Web Science Cochrane, up to May 2023. We incorporated total 70 studies into our analysis. Our findings revealed that prevalence ranged from 25% 73.7%, while it varied 5.2% 62.7%. The both settings included male gender, BMI, malnutrition, osteoarthritis. In these comprised age, poor nutrition status, small calf circumference, smoking, physical inactivity, cognitive impairment, diabetes, depression heart disease. Currently, European Working Group on Sarcopenia Older People (EWGSOP) Asian for (AWGS) standards are widely utilized EWGSOP standard being more applicable homes. Identifying is paramount significance, particularly considering some them can be modified managed. Further research warranted impact preventive measures management among settings.

Язык: Английский

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Association between sarcopenia components and depressed mood varies by sex among community-dwelling older adults from the Korean Frailty and Aging Cohort Study

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Фев. 1, 2025

This cross-sectional study investigated the association between sarcopenia components and depressed mood in community-dwelling adults aged 70–84 years from Korean Frailty Aging Cohort Study. Depressed was assessed using Geriatric Depression Scale short form. Logistic regression used to examine sex-specific associations mood. Among 1,913 participants (mean age: 75.9 years, 49.0% women), 12.2% 23.6% had sarcopenia, respectively. Sarcopenia prevalence increased among individuals with both sexes (men: P < 0.001; women: = 0.016). Severe OR, 3.620; 95% CI, 1.634−8.022; women 3.332; 1.689−6.574) concurrent low muscle strength physical performance 3.660; 1.541−8.691; 2.333; 1.294−4.206) correlated across sexes. The co-occurrence of mass (OR, 2.451; 1.007−5.964) associated men, whereas 2.007; 1.275−3.160) coexistence 1.804; 1.003–3.248) women. were significantly older adults, underscoring need account for differences when evaluating mental health outcomes tailor interventions targeting improve well-being aging populations.

Язык: Английский

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Project 2: Smart Aging

Опубликована: Янв. 1, 2025

Язык: Английский

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Relationship Between Sarcopenia and the Trajectories of Depressive Symptoms Among Chinese Older Adults: The Mediating Effect of Social Participation

International Journal of Behavioral Medicine, Год журнала: 2025, Номер unknown

Опубликована: Апрель 30, 2025

Язык: Английский

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Relationship between Social Support, Sarcopenia, and Cognitive Impairment in Chinese Community-Dwelling Older Adults

The journal of nutrition health & aging, Год журнала: 2023, Номер 27(9), С. 726 - 733

Опубликована: Сен. 1, 2023

Cognitive impairment and sarcopenia have become important challenges for the growing aging population. Social support has been shown to protect against cognitive impairment, but its impact on remains unknown. The purpose of this study was explore correlation between social support, sarcopenia, in Chinese older adults. A multi-stage whole group sampling method used conduct a cross-sectional survey 720 community-dwelling people Shanghai. definition accordance with criteria Asian Working Group Sarcopenia (AWGS) 2019. evaluated using computerized neuropsychological assessment device that had previously validated. assessed Support Rate Scale. Logistic regression analyses were conducted relationship fully adjusting all potential confounding factors. Our found 230 (31.94%) participants 97 (13.47%) sarcopenia. mean score 35.10 ± 7.54. Besides, results showed associated (OR:1.650, 95% CI: 1.048, 2.596, P=0.030) after Older adults high level lowest risk (OR: 0.297, 0.115, 0.680, P=0.021) 0.113, 0.031, 0.407, P=0.001), respectively. analysis revealed negatively impairment. These findings provide strong health promotion effect networks adults, implications healthcare policy makers.

Язык: Английский

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Loss of perceived social role, an index of social frailty, is an independent predictor of future adverse events in hospitalized patients with heart failure

Frontiers in Cardiovascular Medicine, Год журнала: 2022, Номер 9

Опубликована: Дек. 20, 2022

Although the impact of physical frailty on prognosis and effect cardiac rehabilitation in HF patients has been well established, data for prognostic social (SF) are limited. In addition, relative importance each SF domain clinical outcomes remains unclear. We aimed to get a new insight into associations with elderly hospitalized patients.A single-center, retrospective cohort study was conducted using from 310 in-hospital aged ≥ 65 years (mean age 78 ± 8 years; 49% women). Makizako's five questions, self-reported questionnaire, were used define SF. The primary outcome composite events defined by all-cause death cardiovascular events.Of patients, 188 (61%) had Seventy-five (24%) during mean follow-up period 1.93 0.91 years. Kaplan-Meier curves showed that significantly higher event rate than without multivariate Cox regression analyses, independently associated after adjusting markers [adjusted hazard ratio (HR), 2.01; 95% confidence interval (CI), 1.07-3.78; p = 0.04]. Of 5 questions defining SF, an answer yes question about not feeling helpful toward friends or family, which indicates loss perceived role, independent predictor (adjusted HR, 2.28; CI, 1.36-3.82; < 0.01). Inclusion role baseline model improved both continuous net reclassification improvement (0.562; 0.298-0.827; 0.01) integrated discrimination (0.031; 0.006-0.056; 0.02).Loss is increased adverse risk provides additive information patients.

Язык: Английский

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Waist-to-calf circumstance ratio and cognitive function among Chinese older adults: Mediating roles of physical performance and social activity

Frontiers in Aging Neuroscience, Год журнала: 2023, Номер 15

Опубликована: Апрель 17, 2023

Background In light of the potentially detrimental effects central fat and decreased muscle mass on cognitive function, it would be beneficial to learn more about mediating mechanisms underpinning association between two. The purpose this study is determine waist-to-calf circumstance ratio (WCR) as well investigate whether physical performance social activity mediate relationship WCR function among older Chinese adults. Methods An analysis 9,652 adults was conducted during 2018 wave Longitudinal Health Longevity Survey (CLHLS). Mini-Mental State Examination (MMSE) a self-reported scale were used measure performance, activity, respectively. Multiple linear regression mediation analyses conducted. Results findings suggest that high had significant negative with ( B = −0.535, 95% CI: −0.754, −0.317). Mediation revealed influenced old adults' in three ways: first, through partial effect −0.270; −0.340, −0.203); second, −0.035; −0.055, −0.017); third, serial −0.021, −0.029, −0.015). Conclusion results adverse impact possible by which takes place. Multidimensional health interventions aimed at improving physical, social, functioning sarcopenic obesity are recommended.

Язык: Английский

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