Post‐Treatment Apical Periodontitis: Endodontic Infection Contributes to Circulating Microbial DNA DOI Open Access
Yanglin Zeng, Liu Wang, Mudan Wang

и другие.

Australian Endodontic Journal, Год журнала: 2025, Номер unknown

Опубликована: Март 27, 2025

ABSTRACT This study investigated the impact of post‐treatment apical periodontitis on microbial DNA in patients' blood circulation. Samples from root apex, periapical lesion and peripheral 11 patients, along with nine healthy controls, were analysed using next‐generation sequencing. The composition, diversity linear discriminant analysis effect size analysed. SourceTracker was applied to trace microorganisms blood. Proteobacteria dominated lesions, while Actinobacteria prevailed apex. Patients exhibited higher but reduced α‐diversity apex compared other sites. Moreover, Bacteroides , as well Aliihoeflea Oceanicaulis Comamonas Shigella Acinetobacter showed increased relative abundance patients. Additionally, contributed 26% 76% for bacteria. These findings suggested unique translocation

Язык: Английский

Post‐Treatment Apical Periodontitis: Endodontic Infection Contributes to Circulating Microbial DNA DOI Open Access
Yanglin Zeng, Liu Wang, Mudan Wang

и другие.

Australian Endodontic Journal, Год журнала: 2025, Номер unknown

Опубликована: Март 27, 2025

ABSTRACT This study investigated the impact of post‐treatment apical periodontitis on microbial DNA in patients' blood circulation. Samples from root apex, periapical lesion and peripheral 11 patients, along with nine healthy controls, were analysed using next‐generation sequencing. The composition, diversity linear discriminant analysis effect size analysed. SourceTracker was applied to trace microorganisms blood. Proteobacteria dominated lesions, while Actinobacteria prevailed apex. Patients exhibited higher but reduced α‐diversity apex compared other sites. Moreover, Bacteroides , as well Aliihoeflea Oceanicaulis Comamonas Shigella Acinetobacter showed increased relative abundance patients. Additionally, contributed 26% 76% for bacteria. These findings suggested unique translocation

Язык: Английский

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