Frequency of human platelet antigens (HPA) in the Greek population as deduced from the first registry of HPA‐typed blood donors DOI
Georgios Kaltsounis,

Evangelia Boulomiti,

Dimitroula Papadopoulou

и другие.

Vox Sanguinis, Год журнала: 2024, Номер unknown

Опубликована: Сен. 23, 2024

Abstract Background and Objectives Human platelet antigens (HPA) play a central role in foetal neonatal alloimmune thrombocytopenia (FNAIT), post‐transfusion purpura some cases of therapy refractoriness. The frequency distribution HPA had not been studied the Greek population before we started to create registry HPA‐typed apheresis donors. aim this study was determination various population, through establishment typed Materials Methods Here, report on first 1000 donors origin who gave informed consent were genotyped for 12 pairs antithetical by Single Specific Primer‐Polymerase Chain Reaction (SSP‐PCR), including HPA‐1, HPA‐3, HPA‐5 HPA‐15. Antigen frequencies are reported, allele calculated compared with other European non‐European populations. Tested cover all ABO Rhesus D antigen spectrum. Results very similar White HPA‐1bb is 2.9% our study, HPA‐2b, HPA‐4b, HPA‐9b HPA‐15b also slightly higher than literature reports, while found that HPA‐15a. Conclusion We large array clinically significant time population. Frequencies consistent This donors, available donate demand, an important asset treatment FNAIT Greece.

Язык: Английский

HLA-B5 prevalence in patients with spondyloarthritis and impact on disease phenotype: a multicentric case-control study DOI
Nelly Ziadé,

Sarah Bou Jaoude,

Rhéa Nacouzi

и другие.

Lara D. Veeken, Год журнала: 2024, Номер unknown

Опубликована: Июль 16, 2024

The study aimed to estimate the prevalence of HLA-B51 and HLA-B52 in Lebanese patients with spondyloarthritis (SpA) compared healthy controls (HC). We further evaluate impact on phenotype identify distribution alleles HLA-B locus.

Язык: Английский

Процитировано

0
Frequency of human platelet antigens (HPA) in the Greek population as deduced from the first registry of HPA‐typed blood donors DOI
Georgios Kaltsounis,

Evangelia Boulomiti,

Dimitroula Papadopoulou

и другие.

Vox Sanguinis, Год журнала: 2024, Номер unknown

Опубликована: Сен. 23, 2024

Abstract Background and Objectives Human platelet antigens (HPA) play a central role in foetal neonatal alloimmune thrombocytopenia (FNAIT), post‐transfusion purpura some cases of therapy refractoriness. The frequency distribution HPA had not been studied the Greek population before we started to create registry HPA‐typed apheresis donors. aim this study was determination various population, through establishment typed Materials Methods Here, report on first 1000 donors origin who gave informed consent were genotyped for 12 pairs antithetical by Single Specific Primer‐Polymerase Chain Reaction (SSP‐PCR), including HPA‐1, HPA‐3, HPA‐5 HPA‐15. Antigen frequencies are reported, allele calculated compared with other European non‐European populations. Tested cover all ABO Rhesus D antigen spectrum. Results very similar White HPA‐1bb is 2.9% our study, HPA‐2b, HPA‐4b, HPA‐9b HPA‐15b also slightly higher than literature reports, while found that HPA‐15a. Conclusion We large array clinically significant time population. Frequencies consistent This donors, available donate demand, an important asset treatment FNAIT Greece.

Язык: Английский

Процитировано

0