Pakistan Journal of Humanities and Social Sciences,
Год журнала:
2024,
Номер
12(1)
Опубликована: Март 31, 2024
Parenting
is
an
essential
part
in
child’s
rearing
which
directly
and
indirectly
contributes
quality
of
life
wellbeing.
Now
a
days
it
highly
significant
factor
contributing
health
across
all
domains.
Children's
formative
years
experiences
with
regard
to
parenting
have
impact
on
their
development
throughout
lifespan.
Objective
the
study
describe
consequences
maltreatment
children
domain
life.
Especially,
main
focus
psychological
wellbeing
child
being
effected.
This
conducted
by
analyzing
already
published
research
data
from
approximately
last
3
decades.
Qualitative
design
used
for
in-depth
analysis.
After
intensive
literature
analysis
indicated
that
has
great
Furthermore,
also
give
overview
how
parent’s
effects
terms
emotional,
behavioral,
relationships
general
psycho-social
Biomolecules,
Год журнала:
2024,
Номер
14(10), С. 1313 - 1313
Опубликована: Окт. 16, 2024
Background:
The
brain
and
the
intestinal
microbiota
are
highly
interconnected
especially
vulnerable
to
disruptions
in
early
life.
Emerging
evidence
indicates
that
psychosocial
adversity
detrimentally
impacts
microbiota,
affecting
both
physical
mental
health.
This
study
aims
investigate
gut
microbiome
young
children
immediate
aftermath
of
maltreatment
exposure.
Methods:
Maltreatment
exposure
was
assessed
88
(ages
3–7)
using
Maternal
Interview
for
Classification
[MICM].
Children
were
allocated
three
groups
according
number
experienced
categories:
no
maltreatment,
low
high
exposures.
Stool
samples
collected
analyzed
by
16S
rRNA
sequencing.
Results:
subjected
exhibited
lower
alpha
diversity
comparison
those
with
(Simpson
Index,
Tukey
post
hoc,
p
=
0.059
0.007,
respectively).
No
significant
distinctions
beta
identified.
High
associated
enrichment
several
genera
from
class
Clostridia
(Clostridium,
Intestinibacter,
Howardella
Butyrivibrio)
depletion
genus
Phocaeicola
(class
Bacteriodia).
Conclusions:
Severe
is
alterations
children.
Longitudinal
trajectories
composition
context
may
reveal
important
insights
related
psychiatric
somatic
health
outcomes.
Neurobiology of Stress,
Год журнала:
2023,
Номер
27, С. 100576 - 100576
Опубликована: Сен. 23, 2023
Childhood
maltreatment
profoundly
alters
trajectories
of
brain
development,
promoting
markedly
increased
long-term
health
risks
and
impaired
intellectual
development.
However,
the
immediate
impact
on
development
in
children
extent
to
which
altered
global
volume
contributes
with
experience
is
currently
unknown.
We
here
utilized
MRI
data
obtained
from
within
6
months
after
exposure
assess
association
severity
changes.
further
assessed
between
tested
for
mediating
effect
this
association.
used
structural
(3T)
a
sample
49
aged
3–5
years
exposure,
i.e.
emotional
physical
abuse
and/or
neglect
months,
characterize
intracranial
tissue-specific
volumes.
Maltreatment
was
coded
using
Maternal
Interview
Classification
Maltreatment.
IQ
at
study
entry
one
year
Snijders
Oomen
Nonverbal
Test.
Higher
significantly
correlated
smaller
(r
=
-.393,
p
.008),
mainly
driven
by
lower
total
turn
primarily
due
gray
matter
-.454,
.002).
Furthermore,
associated
-.548,
<
.001)
predicted
later
-.493,
.004.).
The
observed
associations
were
independent
potential
confounding
variables,
including
height,
socioeconomic
status,
age
sex.
provide
evidence
that
greater
early
childhood
related
size
very
young
significant
consequences
ability,
likely
setting
path
far-reaching
disadvantages.
Insights
into
molecular
neural
processes
underlie
structure
function
are
urgently
needed
derive
mechanism-driven
targets
intervention.
Developmental Psychobiology,
Год журнала:
2023,
Номер
65(5)
Опубликована: Май 24, 2023
Abstract
The
present
study
illustrates
the
utility
of
latent
class
analysis,
a
person‐centered
data
analytic
approach,
as
an
innovative
method
for
identifying
naturally
occurring
patterns
polygenic
risk,
specifically
within
dopaminergic
system.
Moreover,
this
tests
whether
classes
variation
moderate
effect
child
maltreatment
exposure
on
internalizing
symptoms
among
African
ancestry
youth.
youth
were
selected
because
color
are
overrepresented
in
welfare
system
and
individuals
significantly
underrepresented
genomics
research.
Results
identified
three
gene
variation.
Class
1
was
marked
predominately
by
homozygous
minor
alleles,
2
characterized
major
heterozygous
presentations,
3
alleles
DAT‐1
single‐nucleotide
polymorphisms
(SNPs)
combination
other
SNPs.
indicated
that
greater
number
subtypes
experienced
associated
with
higher
only
children
pattern.
This
distinctly
more
or
allelic
presentations
along
all
significant
environment
interaction
replicated
independent
replication
sample.
Together,
findings
suggest
pattern
specific
vulnerable
to
developing
following
exposure,
relative
their
peers
dopamine‐related
patterns.
Pakistan Journal of Humanities and Social Sciences,
Год журнала:
2024,
Номер
12(1)
Опубликована: Март 31, 2024
Parenting
is
an
essential
part
in
child’s
rearing
which
directly
and
indirectly
contributes
quality
of
life
wellbeing.
Now
a
days
it
highly
significant
factor
contributing
health
across
all
domains.
Children's
formative
years
experiences
with
regard
to
parenting
have
impact
on
their
development
throughout
lifespan.
Objective
the
study
describe
consequences
maltreatment
children
domain
life.
Especially,
main
focus
psychological
wellbeing
child
being
effected.
This
conducted
by
analyzing
already
published
research
data
from
approximately
last
3
decades.
Qualitative
design
used
for
in-depth
analysis.
After
intensive
literature
analysis
indicated
that
has
great
Furthermore,
also
give
overview
how
parent’s
effects
terms
emotional,
behavioral,
relationships
general
psycho-social
