Current Opinion in Lipidology, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 7, 2024
Cardiometabolic diseases (CMDs) increasingly contribute to the cumulative burden of morbidity and mortality worldwide. Here, we reviewed intervention studies using a randomized controlled trial (RCT) design as well meta-analyses RCTs aimed at testing effectiveness different dietary approaches for CMD prevention.
Язык: Английский
Cureus, Год журнала: 2025, Номер unknown
Опубликована: Янв. 6, 2025
This systematic review evaluates the comparative efficacy of low-carbohydrate diets (LCDs) versus low-fat (LFDs) in improving glycemic control, weight management, and lipid profiles individuals with type 2 diabetes mellitus (T2DM) or prediabetes. Seven randomized controlled trials involving diverse populations were included, dietary interventions ranging from very ketogenic (LCK) (typically <10% total caloric intake carbohydrates, higher fat moderate protein) to carbohydrate regimens (30-45% calories). LFDs, contrast, prioritized (50-60% calories), reduced (<20-30%) protein (15-20%). Across studies, LCDs consistently demonstrated greater reductions HbA1c, fasting glucose, triglycerides, alongside superior loss increased high-density lipoprotein cholesterol compared LFDs. Additionally, associated significant medication use, highlighting their potential decrease pharmacological dependency improve metabolic outcomes, including enhanced insulin sensitivity inflammation. Despite variability long-term outcomes adherence, emerged as a promising alternative traditional approaches for managing T2DM. Further research is warranted explore strategies such behavioral technological support, evaluate sustainability, effects on cardiovascular health quality life. These findings underscore transformative management highlight need personalized approaches.
Язык: Английский
Процитировано
1
Cureus, Год журнала: 2025, Номер unknown
Опубликована: Фев. 1, 2025
The effectiveness of calorie restriction (CR) for weight loss in type 2 diabetes mellitus (T2DM) has not been thoroughly studied. This review aims to evaluate CR's short- and long-term its impact on cardiometabolic parameters T2DM. Following Preferred Reporting Items Systematic Reviews Meta-Analyses (PRISMA) guidelines, Medline Complete, Embase, Cumulative Index Nursing Allied Health Literature (CINAHL), Cochrane Library databases were searched identify studies up June 7, 2024. Furthermore, a reference search was conducted. Randomized controlled trials involving adults with T2DM examining CR reporting changes included. revised risk-of-bias tool used assess the study's quality. A narrative synthesis analyze findings. Eleven studies, 1,554 participants, included; all had low risk bias. intervention group participants' mean baseline Body Mass 93.3 kg 32.7 kg/m², respectively. Interventions included total diet replacement (TDR) very low- low-calorie diets lasting 12 weeks two years. TDR resulted >12% loss. Additionally, improved parameters; glycated hemoglobin (HbA1c) decreased ≤6.5%; remission achieved 19% 83%; high-density lipoprotein significantly increased; triglyceride, systolic, diastolic blood pressure decreased. In conclusion, effectively reduces improves markers However, large addressing are lacking, which challenges drawing firm conclusions. highlights need further research address this gap. is registered International Prospective Register (PROSPERO) under registration number CRD42024573505.
Язык: Английский
Процитировано
0
Journal of Health Population and Nutrition, Год журнала: 2025, Номер 44(1)
Опубликована: Апрель 8, 2025
Язык: Английский
Процитировано
0
Journal of Diabetes Investigation, Год журнала: 2024, Номер unknown
Опубликована: Окт. 3, 2024
ABSTRACT Aims Despite the reported success of low‐carbohydrate diets in improving glycemic control Western countries, no studies have investigated effects such Asians. We aimed to conduct a systematic review and meta‐analysis randomized controlled trials examine on East Asian adults. Materials Methods systematically searched PubMed, Cochrane Library, Embase databases from inception June 28, 2023, identify examining efficacy patients with type 2 diabetes (PROSPERO number CRD 42023453007). The primary outcome was difference glycated hemoglobin levels between diet groups. secondary body mass index, fasting blood glucose level, pressure, lipid profile. Results Six met eligibility criteria. study duration ranged 3 18 months, five conducted within 6 months. results showed that were more beneficial lowering index than diets. risk bias for six minimal two moderate four. heterogeneity among low. Conclusions Low‐carbohydrate improved Asians compared Therefore, carbohydrate restriction may be effective management at least
Язык: Английский
Процитировано
2
Current Opinion in Lipidology, Год журнала: 2024, Номер unknown
Опубликована: Ноя. 7, 2024
Cardiometabolic diseases (CMDs) increasingly contribute to the cumulative burden of morbidity and mortality worldwide. Here, we reviewed intervention studies using a randomized controlled trial (RCT) design as well meta-analyses RCTs aimed at testing effectiveness different dietary approaches for CMD prevention.
Язык: Английский
Процитировано
0