Wine: is it really healthy? DOI

Ramón Estruch

Clínica e Investigación en Arteriosclerosis (English Edition), Год журнала: 2023, Номер 35(6), С. 294 - 296

Опубликована: Ноя. 1, 2023

Язык: Английский

Reducing the harms of alcohol: nutritional interventions and functional alcohol alternatives DOI
Delia Belelli, Antonio Riva, David Nutt

и другие.

International review of neurobiology, Год журнала: 2024, Номер unknown, С. 241 - 276

Опубликована: Янв. 1, 2024

Язык: Английский

Процитировано

0
Water decoction of Pericarpium citri reticulatae and Amomi fructus ameliorates alcohol-induced liver disease involved in the modulation of gut microbiota and TLR4/NF-κB pathway DOI Creative Commons
Xingmin Zhang,

Yuechang Huang,

Baizhong Chen

и другие.

Frontiers in Pharmacology, Год журнала: 2024, Номер 15

Опубликована: Июнь 20, 2024

Introduction Alcohol consumption alters the diversity and metabolic activities of gut microbiota, leading to intestinal barrier dysfunction contributing development alcoholic liver disease (ALD), which is most prevalent cause advanced diseases. In this study, we investigated protective effects action mechanism an aqueous extraction Pericarpium citri reticulatae Amomi fructus (PFE) on injury. Methods C57BL/6 mice were used establish mouse model injury orally administered 500 1,000 mg/kg/d PFE for 2 weeks. Histopathology, immunohistochemistry, immunofluorescence, Western blotting, qRT-PCR, 16S rDNA amplicon sequencing analyze in treatment alcohol-induced Results Treatment with significantly improved injury, as illustrated by normalization serum alanine aminotransferase, aspartate total triglyceride, cholesterol levels ALD a dose-dependent manner. Administration not only maintained integrity prominently upregulating mucous production tight junction protein expressions but also sensibly reversed dysregulation microecology alcohol-treated mice. Furthermore, reduced hepatic lipopolysaccharide (LPS) attenuated oxidative stress well inflammation related TLR4/NF-κB signaling pathway. The supplementation promoted short-chain fatty acids (SCFAs) Conclusion effectively prevents may regulate LPS-involved gut–liver axis; could provide valuable insights drugs prevent treat ALD.

Язык: Английский

Процитировано

0
EL VINO: ¿ES REALMENTE SALUDABLE? DOI

Ramón Estruch

Clínica e Investigación en Arteriosclerosis, Год журнала: 2023, Номер 35(6), С. 294 - 296

Опубликована: Ноя. 1, 2023

Процитировано

0
Wine: is it really healthy? DOI

Ramón Estruch

Clínica e Investigación en Arteriosclerosis (English Edition), Год журнала: 2023, Номер 35(6), С. 294 - 296

Опубликована: Ноя. 1, 2023

Язык: Английский

Процитировано

0