Anatomy and mobility in the adult cadaveric craniocervical junction DOI Creative Commons
M.A.M. Taverne,

Laura Laliève,

Sylvain Persohn

и другие.

Journal of Morphology, Год журнала: 2024, Номер 285(7)

Опубликована: Июнь 27, 2024

Genetic diseases with craniofacial malformations can be associated anomalies of the craniocervical joint (CCJ). The functions CCJ are thus impaired, as mobility may either limited by abnormal bone fusion causing headaches, or exaggerated in case hypermobility, which cause irreparable damage to spinal cord. Restoring balance between and stability requires surgical correction children. anatomy biomechanics quite unique, yet have been overlooked past decades. Pediatric evidence is so scarce, that investigating adult our best shot disentangle form-function relationships this anatomical region. motivation present study was understand morphological functional basis motion CCJ, hope find features accessible from medical imaging able predict mobility. To do so, we quantified in-vitro kinematics nine cadaveric asymptomatic adults, estimated a wide range variables covering complexity motion. We compared these shape occipital, atlas axis, obtained using dense geometric morphometric approach. Morphological congruence also quantified. Our results suggest strong relationship motion, overall geometry predicting primary movements, facets secondary movements. propose hypothesis stating musculoligamental system determines movements great amplitude, while determine coupled especially varying stops way ligaments tensioned. believe work will provide valuable insights understanding CCJ. Furthermore, it should help surgeons treating enabling them translate objectives clinical outcome into clear outcome.

Язык: Английский

Geometric growth of the normal human craniocervical junction from 0 to 18 years old DOI Creative Commons
Juliette Raoul‐Duval,

Angèle Ganet,

Sandro Benichi

и другие.

Journal of Anatomy, Год журнала: 2024, Номер 245(6), С. 842 - 863

Опубликована: Май 23, 2024

Abstract The craniocervical junction (CCJ) forms the bridge between skull and spine, a highly mobile group of joints that allows mobility head in every direction. CCJ plays major role protecting inferior brainstem (bulb) spinal cord, therefore also requiring some stability. Children are subjected to multiple constitutive or acquired diseases involving CCJ: primary bone such as FGFR ‐related craniosynostoses conditions congenital torticollis, cervical spine luxation, neurological disorders. To design efficient treatment plans, it is crucial understand relationship abnormalities craniofacial region CCJ. This can be approached by study control abnormal growth patterns. Here we report model normal base compiling collection geometric models children. Focused analyses highlighted specific developmental patterns for each bone, emphasizing rapid during infancy, followed varying rates maturation childhood adolescence until reaching stability 18 years age. focus was on closure synchondroses sutures occipital revealing distinct trajectories anterior intra‐occipital occipitomastoid suture. findings, although based limited dataset, showcased age‐related changes width percentages, providing valuable insights into dynamics within first 2 life. Integration revealed intricate relationships neck structures, coordinated at different stages. Specific covariation patterns, found second vertebrae (C1 C2), indicated synchronized morphological changes. Our results provide initial data designing inclusive predict dynamics.

Язык: Английский

Процитировано

2
Anatomy and mobility in the adult cadaveric craniocervical junction DOI Creative Commons
M.A.M. Taverne,

Laura Laliève,

Sylvain Persohn

и другие.

Journal of Morphology, Год журнала: 2024, Номер 285(7)

Опубликована: Июнь 27, 2024

Genetic diseases with craniofacial malformations can be associated anomalies of the craniocervical joint (CCJ). The functions CCJ are thus impaired, as mobility may either limited by abnormal bone fusion causing headaches, or exaggerated in case hypermobility, which cause irreparable damage to spinal cord. Restoring balance between and stability requires surgical correction children. anatomy biomechanics quite unique, yet have been overlooked past decades. Pediatric evidence is so scarce, that investigating adult our best shot disentangle form-function relationships this anatomical region. motivation present study was understand morphological functional basis motion CCJ, hope find features accessible from medical imaging able predict mobility. To do so, we quantified in-vitro kinematics nine cadaveric asymptomatic adults, estimated a wide range variables covering complexity motion. We compared these shape occipital, atlas axis, obtained using dense geometric morphometric approach. Morphological congruence also quantified. Our results suggest strong relationship motion, overall geometry predicting primary movements, facets secondary movements. propose hypothesis stating musculoligamental system determines movements great amplitude, while determine coupled especially varying stops way ligaments tensioned. believe work will provide valuable insights understanding CCJ. Furthermore, it should help surgeons treating enabling them translate objectives clinical outcome into clear outcome.

Язык: Английский

Процитировано

0